Search results for "Simulation"

2019

This paper describes a single body-mounted sensor that integrates accelerometers, gyroscopes, compasses, barometers, a GPS receiver, and a methodology to process the data for biomechanical studies. The sensor and its data processing system can accurately compute the speed, acceleration, angular velocity, and angular orientation at an output rate of 400 Hz and has the ability to collect large volumes of ecologically-valid data. The system also segments steps and computes metrics for each step. We analyzed the sensitivity of these metrics to changing the start time of the gait cycle. Along with traditional metrics, such as cadence, speed, step length, and vertical oscillation, this system est…

An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era

2017

Introduction: Metallo-drugs have attracted enormous interest for cancer treatment. The achievements of this drug-type are summarized by the success story of cisplatin. That being said, there have been many drawbacks with its clinical use, which prompted decades worth of research efforts to move towards safer and more effective agents, either containing platinum or different metals. Areas covered: In this review, the authors provide an atomistic picture of the molecular mechanisms involving selected metallo-drugs from structural and molecular simulation studies. They also provide an omics perspective, pointing out many unsettled aspects of the most relevant families of metallo-drugs at an ep…

An abstract inf-sup problem inspired by limit analysis in perfect plasticity and related applications

2021

This paper is concerned with an abstract inf-sup problem generated by a bilinear Lagrangian and convex constraints. We study the conditions that guarantee no gap between the inf-sup and related sup-inf problems. The key assumption introduced in the paper generalizes the well-known Babuška–Brezzi condition. It is based on an inf-sup condition defined for convex cones in function spaces. We also apply a regularization method convenient for solving the inf-sup problem and derive a computable majorant of the critical (inf-sup) value, which can be used in a posteriori error analysis of numerical results. Results obtained for the abstract problem are applied to continuum mechanics. In particular…

Elaboración y validación biomecánica de un guante de protección para jugar a pelota valenciana. (Elaboration and biomechanical validation of a protec…

2012

ResumenLa pelota valenciana es uno de los antiguos juegos de pelota a mano que perdura en la Comunidad Valenciana. Para amortiguar los impactos de la pelota durante el golpeo, los jugadores se confeccionan sus propias protecciones. En torno a ellas existen diversos factores que dificultan la práctica segura y eficaz de este deporte: el excesivo tiempo empleado en su elaboración, el elevado número de lesiones que sufren en las manos o el inadecuado control de la pelota que consiguen. En base a esto y a la inexistencia de un equipamiento deportivo específico para la mano, se ha desarrollado y validado un guante para intentar solventar estos inconvenientes. En la validación biomecánica se comp…

Representation of NURBS surfaces by Controlled Iterated Functions System automata

2019

Iterated Function Systems (IFS) are a standard tool to generate fractal shapes. In a more general way, they can represent most of standard surfaces like Bézier or B-Spline surfaces known as self-similar surfaces. Controlled Iterated Function Systems (CIFS) are an extension of IFS based on automata. CIFS are basically multi-states IFS, they can handle all IFS shapes but can also manage multi self-similar shapes. For example CIFS can describe subdivision surfaces around extraordinary vertices whereas IFS cannot. Having a common CIFS formalism facilitates the development of generic methods to manage interactions (junctions, differences...) between objects of different natures.This work focuses…

Real Time Image Rotation Using Dynamic Reconfiguration

2002

Abstract Field programmable gate array (FPGA) components are widely used nowdays to implement various algorithms, such as digital filtering, in real time. The emergence of dynamically reconfigurable FPGAs made it possible to reduce the number of necessary resources to carry out an image-processing task (tasks chain). In this article, an image-processing application, image rotation, that exploits the FPGAs dynamic reconfiguration method is presented. This paper shows that the choice of an implementation, static or dynamic reconfiguration, depends on the nature of the application. A comparison is carried out between the dynamic and the static reconfiguration using two criteria: cost and perfo…

Enhancing HSUPA system level performance with dual carrier capability

2010

The purpose of this paper is to analyze how dual carrier capability can enhance High Speed Uplink Packet Access performance in comparison to using only single carrier. Dual carrier operation gives the User Equipment the possibility to transmit simultaneously using two 5 MHz bands, theoretically doubling the peak data rates and user throughput. The analysis is conducted with a system level simulation tool. This paper first indicates with single carrier simulations that, especially in small cells, terminals have spare power available for dual carrier operation. These observations are verified with dual carrier simulations by showing that the burst throughput can be practically doubled. In the…

Power estimation for non-standardized multisite studies

2016

A concern for researchers planning multisite studies is that scanner and T1-weighted sequence-related biases on regional volumes could overshadow true effects, especially for studies with a heterogeneous set of scanners and sequences. Current approaches attempt to harmonize data by standardizing hardware, pulse sequences, and protocols, or by calibrating across sites using phantom-based corrections to ensure the same raw image intensities. We propose to avoid harmonization and phantom-based correction entirely. We hypothesized that the bias of estimated regional volumes is scaled between sites due to the contrast and gradient distortion differences between scanners and sequences. Given this…

A self-adaptable distributed CBR version of the EquiVox system

2016

Three dimensional (3D) voxel phantoms are numerical representations of human bodies, used by physicians in very different contexts. In the controlled context of hospitals, where from 2 to 10 subjects may arrive per day, phantoms are used to verify computations before therapeutic exposure to radiation of cancerous tumors. In addition, 3D phantoms are used to diagnose the gravity of accidental exposure to radiation. In such cases, there may be from 10 to more than 1000 subjects to be diagnosed simultaneously. In all of these cases, computation accuracy depends on a single such representation. In this paper, we present EquiVox which is a tool composed of several distributed functions and enab…

An advanced system for the simulation and planning of orthodontic treatment

2000

This paper presents a new system for three-dimensional (3-D) orthodontic treatment planning and movement of teeth. We describe a computer vision technique for the acquisition and processing of 3-D images of the profile of hydrocolloid dental imprints. Profile measurement is based on the triangulation method which detects deformation of the projection of a laser line on the dental imprints. The system is computer-controlled and designed to achieve depth and lateral resolutions of 0.1 and 0.2 mm, respectively, within a depth range of 40 mm. The 3-D image of the imprint is segmented in order to identify different teeth. Two operators are presented: one for the detection of molars and premolars…