Search results for "Single"

showing 10 items of 4920 documents

Colorectal cancer: pharmacogenetics support for the correct drug prescription

2019

Pharmacogenetics (PGx) in clinical practice is a tool that the clinician can use to guide, in a personalized way, the most suitable treatment that will be administered to the patient. The objective of this review is to summarize in a practical and accessible rational way, the advances that currently exist for the application of PGx in colorectal cancer chemotherapy management through the study of the patients’ germline polymorphisms. To define the polymorphisms that can be applied, we rely on three fundamental cornerstones: the recommendations of drug regulatory agencies; the implementation guidelines prepared by expert consortia in PGx and information from clinical annotations (the drug/p…

Drugmedicine.medical_specialtyPharmGKBColorectal cancermedia_common.quotation_subjectAntineoplastic AgentsDrug PrescriptionsPolymorphism Single NucleotideGeneticsmedicineAnimalsHumansPrecision MedicineMedical prescriptionIntensive care medicinemedia_commonPharmacologybusiness.industryfood and beveragesEvidence-based medicinemedicine.diseaseClinical PracticePharmacogeneticsMolecular MedicineColorectal NeoplasmsbusinessPharmacogeneticsPharmacogenomics
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797 Infliximab in the Treatment of Pediatric Ibd: A Single Centre Experience

2010

Background and aims: The biological treatment of IBD acts on different stages of immunophysiopathological processes of the disease. We describe evolution and clinical response to Infliximab in paediatric patients affected by IBD diagnosed and followed at our centre. Methods: In the last triennial period at our Department of Paediatrics in Palermo 53 infusions of Infliximab were administrated to our patients affected by severe forms of IBD. All patients but one were affected by several forms of CD. Only one child was affected by U.C. associated to pyoderma gangrenosum. The total number of infusions were administrated according the ACCENT 1 study at a dose of 5 mg/Kg. All the infusions were p…

Drugmedicine.medical_specialtybusiness.industrymedia_common.quotation_subjectDiseasemedicine.diseaseInfliximabDiscontinuationSingle centreTolerabilityInternal medicinePediatrics Perinatology and Child HealthmedicinebusinessPyoderma gangrenosummedia_commonPaediatric patientsmedicine.drugPediatric Research
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Substituent-induced coupling of the two lowest excited singlet states of 2-methoxy-derivatives of 4-(N,N-dimethylamino)- and 4-(N-methylamino)benzoni…

2002

The title compounds both exhibit strong features of interaction of their two lowest excited states, but only one of them, the dimethylamino derivative, exhibits dual fluorescence. This is a direct indication that state interaction and dual fluorescence are not directly related.

Dual fluorescenceCoupling (electronics)chemistry.chemical_compoundBenzonitrilechemistryExcited stateSubstituentGeneral Physics and AstronomyPhysical and Theoretical ChemistryPhotochemistryMedicinal chemistryExcited singletPhysical Chemistry Chemical Physics
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Organic Dye Bearing Asymmetric Double Donor-π-Acceptor Chains for Dye-Sensitized Solar Cells

2011

A novel efficient metal free sensitizer containing asymmetric double donor-π-acceptor chains (DC) was synthesized for dye-sensitized solar cells (DSSCs). Comparing to 3.80%, 4.40% and 4.64% for the DSSCs based on the dyes with single chain (SC1, SC2) and cosensitizers (SC1 + SC2), the overall conversion efficiency reaches 6.06% for DC-sensitized solar cells as a result of its longer electron lifetime and higher incident monochromatic photon-to-current conversion efficiency.

Dye-sensitized solar cellBearing (mechanical)Metal freeChemistrylawOrganic ChemistryOrganic dyeEnergy conversion efficiencySingle chainMonochromatic colorPhotochemistryAcceptorlaw.inventionThe Journal of Organic Chemistry
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"Table 1" of "Inclusive cross sections, charge ratio and double-helicity asymmetries for $\pi^+$ and $\pi^-$ production in $p$$+$$p$ collisions at $\…

2016

Invariant cross section for $\pi^+$ and $\pi^-$ hadrons, as well as the statistical and systematic uncertainties. In addition, there is an absolute scale uncertainty of 9.6$\%$.

E*D3SIG/DP**3InclusiveSingle Differential Cross SectionProton-Proton ScatteringHigh Energy Physics::ExperimentDSIG/DPTP P --> PI+ XP P --> PI- XTransverse Momentum DependenceInvariant Cross Section200.0
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"Table 31" of "Tuning and test of fragmentation models based on identified particles and precision event shape data."

1996

Differential 4-jet rate for the Durham Algorithm. Corrected to final state particles. YCUT is the jet finding cutt-off parameter.

E+ E- --> 4JETDN/DSIGAstrophysics::High Energy Astrophysical PhenomenaE+ E- ScatteringExclusiveHigh Energy Physics::Experiment91.2Single Differential DistributionJet ProductionComputer Science::Distributed Parallel and Cluster Computing
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"Table 3" of "Exclusive production of pion and kaon meson pairs in two photon collisions at LEP."

2003

Measured cross section for pion production as a function of W.

E+ E- --> E+ E- PI+ PI-DSIG/DMElectron productionHigh Energy Physics::LatticeNuclear TheoryIntegrated Cross SectionGAMMA GAMMA --> PI+ PI-Cross SectionSIG0.0Single Differential Cross SectionPhotoproductionE+ E- ScatteringTwo-PhotonExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 1" of "Exclusive production of pion and kaon meson pairs in two photon collisions at LEP."

2003

Measured angular distribution for pion production.

E+ E- --> E+ E- PI+ PI-Electron productionHigh Energy Physics::LatticeNuclear TheoryGAMMA GAMMA --> PI+ PI-0.0Single Differential Cross SectionPhotoproductionE+ E- ScatteringDSIG/DCOSTHETATwo-PhotonExclusiveHigh Energy Physics::ExperimentNuclear ExperimentAngular Dependence
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"Table 47" of "Tuning and test of fragmentation models based on identified particles and precision event shape data."

1996

XP distribution for F0(980) production.. Data read from plot.

E+ E- --> F0(980) XDN/DXInclusiveE+ E- Scattering91.2Single Differential Distribution
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"Table 1" of "Measurement of inclusive rho0, f0(980), f2(1270), K*2(1430)0 and f'2(1525) production in Z0 decays."

1999

Differential production cross sections. The error is the quadratic combination of the errors from the fits and the systematic uncertainty.

E+ E- --> F0(980) XInclusiveSingle Differential Cross SectionE+ E- --> F2(1270) XE+ E- --> Z0E+ E- ScatteringExclusive91.2DSIG/DXE+ E- --> RHO0 X
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