Search results for "Small"

Profil współczesnej opiekunki małych dzieci

2017

Ostatnie lata przynoszą duże zainteresowanie problematyką pozarodzinnej opieki nad małym dzieckiem. Poszukując najlepszych rozwiązań w tym zakresie nie sposób pominąć instytucji opiekunki dziecięcej, która od wielu lat na trwale wpisuje się w ów system. W publikacji podjęto temat niani, zarówno w płaszczyźnie teoretycznej, z uwzględnieniem rysu historycznego a także uregulowań prawnych, jak i badawczego - przeanalizowano 98 ofert, które w ostatnich dwóch latach pojawiły się na portalu internetowym www.niania/pl/opiekunka/opole. Ich analiza pozwoliła nakreślić profil rozwojowy współczesnej opiekunki małych dzieci jako osoby młodej, wykształconej, z pewnym doświadczeniem zawodowym, gotową wyk…

Demographic characterization and genetic variability of the Girgentana goat breed by the analysis of genealogical data

2004

The aim of this paper is to present an overview of the actual Sicilian Girgentana population structure by the analysis ofgenealogical data. Statistics show that in 1983 the population consisted of 30,000 Girgentana goats; ten years lateralmost 98% of the entire Girgentana population disappeared. The remaining population consists of 461 individuals (134males and 327 females), with 368 living animals. The effective population size is 380 individuals. The inbreeding rate pergeneration was equal to 0.13%. The average estimated inbreeding level within the living male population was equal to0.8% (0-15%); and the average inbreeding level within the living female population was equal to 0.7% (0-31%…

On sampling error in evolutionary algorithms

2021

The initial population in evolutionary algorithms (EAs) should form a representative sample of all possible solutions (the search space). While large populations accurately approximate the distribution of possible solutions, small populations tend to incorporate a sampling error. A low sampling error at initialization is necessary (but not sufficient) for a reliable search since a low sampling error reduces the overall random variations in a random sample. For this reason, we have recently presented a model to determine a minimum initial population size so that the sampling error is lower than a threshold, given a confidence level. Our model allows practitioners of, for example, genetic pro…

The voyage of an invasive species across continents: genetic diversity of North American and European Colorado potato beetle populations

2005

The paradox of successful invading species is that they are likely to be genetically depauperate compared to their source population. This study on Colorado potato beetles is one of the few studies of the genetic consequences of continent-scale invasion in an insect pest. Understanding gene flow, population structure and the potential for rapid evolution in native and invasive populations offers insights both into the dynamics of small populations that become successful invaders and for their management as pests. We used this approach to investigate the invasion of the Colorado potato beetle (Leptinotarsa decemlineata) from North America to Europe. The beetles invaded Europe at the beginnin…

Call admission control scheme using borrowable guard channels and prioritizing fresh calls retrials in small cell networks

2014

International audience; Recent trends in mobile cellular networks turn towards deployment of Small Cell Networks (SCNs), where, the cell size gets smaller, and thus the number of subscribers served in a cell will be relatively smaller, such that traffic models with a finite source of subscribers should be considered. Smaller cells cause the mobile subscribers to cross several cells during an ongoing conversation resulting in frequent handovers. Most of works dealing with Call Admission Control (CAC) problems based on guard channels scheme in cellular mobile networks consider models without retrials (reapeted calls phenomenon). However, almost all existing works which take into account retri…

Current understanding of genetic polymorphisms as biomarkers for risk of biological complications in implantology

2018

Background In the last decade, multiple studies have been published that analyze the relationship between the risk of experiencing biological complications with implants and the presence of certain types of genetic polymorphisms. In the present report, we analyze the controversies that have arisen from this important area of investigation and synthesize the most prominent aspects of knowledge related to this possible etiopathogenic relationship. Material and methods For this review, the biomedical databases PubMed-Medline, SciELO, and DOAJ were used. Different search strategies were employed, from which 298 articles initially emerged. After refinement of the search, 55 articles published be…

Multiple pregnancies and environmental exposure: An impact of air pollution on fetal growth?

2018

Introduction Multiple pregnancies display all the complications of singletons, but in highest frequencies, especially for fetal growth abnormalities. In singletons, air pollution seems to be negatively associated with fetal growth. A similar relationship in multiple pregnancies can be expected. However, multiple pregnancies are systematically excluded from the studies of the impact of air pollution on pregnancy outcomes. This study aims to analyze in a population of multiple pregnancies the relationship between fetal growth restriction (FGR), small for gestational age (SGA) and environmental chronic exposure to air pollution in moderately polluted cities. Methods All the multiple pregnancie…

Mikrojärjestelmien virtausdynamiikka numeerisen mallintamisen näkökulmasta

2005

Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases.

2008

The receptor for advanced glycation end products (RAGE) is a 55-kDa type I membrane glycoprotein of the immunoglobulin superfamily. Ligand-induced up-regulation of RAGE is involved in various pathophysiological processes, including late diabetic complications and Alzheimer disease. Application of recombinant soluble RAGE has been shown to block RAGE-mediated pathophysiological conditions. After expression of full-length RAGE in HEK cells we identified a 48-kDa soluble RAGE form (sRAGE) in the culture medium. This variant of RAGE is smaller than a 51-kDa soluble version derived from alternative splicing. The release of sRAGE can be induced by the phorbol ester PMA and the calcium ionophore c…

Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish.

2020

ABSTRACT Primordial germ cells (PGCs) are the precursors of germ cells, which migrate to the genital ridge during early development. Relatively little is known about PGCs after their migration. We studied this post-migratory stage using microscopy and sequencing techniques, and found that many PGC-specific genes, including genes known to induce PGC fate in the mouse, are only activated several days after migration. At this same time point, PGC nuclei become extremely gyrated, displaying general broad opening of chromatin and high levels of intergenic transcription. This is accompanied by changes in nuage morphology, expression of large loci (PGC-expressed non-coding RNA loci, PERLs) that ar…