Search results for "Small"
showing 10 items of 2441 documents
Sperm morphological abnormalities appearing in the male rabbit reproductive tract
1996
The role of the excurrent duct system in producing and/or eliminating morphologically abnormal spermatozoa may modify the semen parameters and interfere with sperm fertilizing capacity. To study this process, changes in the morphology of spermatozoa during their transit through the reproductive tract in sexually mature rabbits were investigated. The incidence of head, midpiece and tail abnormalities as well as of multiple defects in a single spermatozoon, and the position of the cytoplasmic droplet along the sperm midpiece were evaluated in samples from the testis, 6 regions of the epididymis and the vas deferens. Spermatozoa were characterized by rapid migration of the cytoplasmic droplet …
Summary of Week VII
2018
International audience; Week VII of the INT program 2018 “Probing Nucleons and Nuclei in High Energy Collisions” was dedicated to topics at the interface of the electron-ion collider (EIC), heavy ion and proton-nucleus collisions. The EIC will provide complementary tools to investigate and constrain the initial state in HIC collisions, as well as transport properties of QCD matter which can be extracted from observables that are sensitive to final states interactions such as pt-broadening and energy loss. The contributed talks and discussions covered a variety of physics topics from saturation physics and the origin of multi-particle correlations in HIC to jet quenching and the strong coupl…
Entrepreneurial Marketing in Small Firms: A Comparative Study of Small Software Technology Firms in Central Finland, Wales, UK and Silicon Valley, US
2015
This paper reports on present research of Entrepreneurial Marketing (EM) in small software technology firms (SSTFs) in order to investigate and compare the effects of ecosystems in three different countries and, the effect this has on a firm’s EM orientation and, on business growth. Firms today operate in a business environment characterized by increased risk and decreased ability to forecast while markets are uncertain, are fragmenting and becoming frictionless. Hence, firms interact as competitors, customers, and collaborators in a global, knowledge economy. Such changes have had an effect on marketing (Schindehutte, Morris and Pitt 2008) and reflect the type of marketing practiced in sma…
In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs
2019
Beagle dog is a standard animal model for evaluating nonclinical pharmacokinetics of new drug candidates. Glucuronidation in intestine and liver is an important first-pass drug metabolic pathway, especially for phenolic compounds. This study evaluated the glucuronidation characteristics of several 7-hydroxycoumarin derivatives in beagle dog's intestine and liver in vitro. To this end, glucuronidation rates of 7-hydroxycoumarin (compound 1), 7-hydroxy-4-trifluoromethylcoumarin (2), 6-methoxy-7-hydroxycoumarin (3), 7-hydroxy-3-(4-tolyl)coumarin (4), 3-(4-fluorophenyl)coumarin (5), 7-hydroxy-3-(4-hydroxyphenyl)coumarin (6), 7-hydroxy-3-(4-methoxyphenyl)coumarin (7), and 7-hydroxy-3-(1H-1,2,4-t…
I vari modi del DNA di “parlare” ai viventi fra ciò che già è noto e nuove scoperte
2018
A sessant’anni da quando Francis Crick enunciò il “dogma centrale della biologia molecolare” molte scoperte e nuove frontiere si sono avvicendate sulla questione “funzionale” di un genoma, cioè di come un DNA “parla” ai viventi. Oggi è abbastanza noto come un genoma “è”, ed occuparsi solo di questa questione strutturale ormai è sicuramente molto riduttivo, almeno sicuramente per quello umano. È invece il goal standard di questi anni scoprire come e quando un genoma si esprime, come funzio-nalmente traduce il suo messaggio rendendo questo visibile nei fe-notipi dei viventi, a prescindere dalla sua sequenza primaria di basi azotate. Ne consegue che il codice genetico, ancora valido e quasi un…
IT-Supported International Subsidiary Establishment Process for the Japanese Market: A Case Study on Finnish High Technology SMEs
2005
The large size of the Japanese IT market makes it attractive to and important for foreign high technology companies. However, the Japanese market is very challenging, highly competitive, and difficult to penetrate for foreign small and medium-sized enterprises (SMEs). Most SMEs fail to penetrate into the Japanese market effectively by using modern IT-tools in the international subsidiary establishment process. No earlier in-depth empirical research exists on the IT-supported international subsidiary establishment process for this market. This study investigated and analyzed how a Finnish high technology SME implemented the ITsupported international subsidiary establishment process for the J…
Perceptions about Boards in Sme Sized Family Businesses
2009
This paper reports on a study of the attitudes to the formation and roles of formalised active boards in Australian small to medium sized (SME) family businesses. While the literature on governance includes guidelines for effective boards, many family owned businesses perceive they are functioning adequately without formalising a board structure. This study employed a qualitative approach and explored the board functions of nine family business cases drawing on the Hilmer and Tricker (1994) framework. This framework summarises the roles of boards as: formulating strategy, setting policies, supervising executive management and providing accountability. Cases included those with and without a…
The phenomenon of family business and taxation
2021
Our research aims to explore and understand specifics of taxation for family business. We have to appreciate the potential of small-scale entrepreneurship, social business, family sustenance farming, mutual support within communities considering neglected policy options, finding ways to reduce obstacles built by conventional conceptualizations of economics. Survivability - the necessary step to sustainability in hard times; taxation policy should have its say. The authors believe that small-scale entrepreneurship, family business is the one of the most important economy development factors political and social condition stabilization.
Internationalization pathways of family SMEs: psychic distance as a focal point
2010
Purpose – The purpose of this paper is to investigate how psychic distance affects the internationalization process, foreign market entry (FME), and entry mode choice of Finnish small and medium-sized family enterprises (family SMEs) operating in France. Design/methodology/approach – The paper reports findings from an in-depth case study covering four Finnish manufacturing family SMEs operating in the French market. The data were analyzed using the Uppsala model and distance creating and distance-bridging factors encountered in the FME to France. Findings – The findings reveal that the family SMEs mainly followed a sequential process and favored indirect entry modes before entering the Fren…
Physicochemical investigation of acrylamide solubilization in sodium bis(2-ethylhexyl)sulfosuccinate and lecithin reversed micelles.
2003
The state of acrylamide confined within dry sodium bis(2-ethylhexyl)sulfosuccinate (AOT) and lecithin reversed micelles dispersed in CCl4 has been investigated by FTIR and H-1 NMR spectroscopy. Measurements have been performed at 25 degreesC as a function of the acrylamide-to-surfactant molar ratio (R) at a fixed surfactant concentration (0.1 mol kg(-1)). The analysis of experimental data, corroborated by the results of SAXS measurements, is consistent with the hypothesis that acrylamide is quite uniformly distributed among reversed micelles mainly located in proximity to the surfactant head-group region and that its presence induces significant unidimensional growth of micellar aggregates.…