Search results for "Small"

A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer mixed micelles

2019

Abstract Hypothesis Doxorubicin hydrochloride (DX) is one of the most powerful anticancer agents though its clinical use is impaired by severe undesired side effects. DX encapsulation in nanocarrier systems has been introduced as a mean to reduce its toxicity. Micelles of the nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (PEO-PPO-PEO), are very promising carrier systems. The positive charge of DX confines the drug to the hydrophilic corona region of the micelles. The use of mixed micelles of PEO-PPO-PEO copolymers and a negatively charged bile salt should favour the solubilization of DX in the apolar core region of the micelles. Experiments We st…

Virtual Reality, Augmented Reality, and In Vivo Exposure Therapy: A Preliminary Comparison of Treatment Efficacy in Small Animal Phobia

2018

This study aggregated data from three randomized control trials to explore the differential efficacy of three forms of exposure therapy, namely, in vivo (iVET), virtual reality (VRET), and augmented reality (ARET), in the treatment of small animal phobia. Additionally, baseline patient characteristics were used to detect subgroups of patients who showed a differential response to certain treatment modalities. Primary measures were distance covered, anxiety during the behavioral avoidance test (BAT), and overall fear of small animals. A repeated-measures analysis of variance was used to explore the overall treatment effect across the exposure modalities. A cluster analysis and an analysis of…

Small area estimation with linear mixed models from unit-level panel and rotating panel data

2009

Creating Managerial Ethical Profiles: An Exploratory Cluster Analysis

2008

This study profiles managers according to the ethical criteria they bring to their managerial decision making. Profiling was based on exploratory cluster analysis of responses of academics & students and small business managers to a multidimensional questionnaire. The data were collected through a self-reporting survey (n=82) administrated to the two cohorts. An agglomerative hierarchical cluster analysis was then performed to the two groups separately on the 8 ethical subscales from the Managerial Ethical Profile (MEP). Between-groups linkage method and squared binary Euclidean distance measures were used to cluster groups in the given data sets. Five clusters were found as an optimal numb…

A Family Dimension in SME Owner-Managers Ownership Profiles A Psychological Ownership Perspective

2008

This paper introduces a contextual model of ownership that consists of social, action and object dimensions. We build on business ownership and family business literatures as well as that of the psychology of ownership to analyze small business owner-managers’ ownership profiles. In the empirical section we show that distinct ownership profiles can be identified and that those owner-managers who view their business as a family business have distinct profiles from those of non-family business owners. Our analysis shows that family business profiles include care-taking, stewardship and continuity as well as a perception of the company as a tool for achieving other valuable things in the world…

Who needs to care about small, dense low density lipoproteins?

2007

Background: Increasing evidence suggest that the ‘quality’ rather than only the ‘quantity’ of low-density lipoprotein (LDL) exerts a great influence on the cardiovascular risk. Small, dense LDL seem to be an important predictor of cardiovascular events and progression of coronary artery disease (CAD) and their predominance has been accepted as an emerging cardiovascular risk factor by the National Cholesterol Education Program Adult Treatment Panel III. Discussion: Some studies showed in past years that small, dense LDL are usually elevated in patients at very high cardiovascular risk, such as those with CAD and type 2 diabetes. More recently elevated levels of these particles have been fou…

Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL.

2022

Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing future cardiovascular events. Low-density lipoproteins (LDL) have been successfully targeted, and their reduction is one of the key preventing measures in patients with atherosclerotic disease. LDL particles are pivotal for the formation and progression of atherosclerotic plaques; yet, they are quite heterogeneous, and smaller, denser LDL species are the most atherogenic. These particles have greater arterial entry and retention, higher susceptibility to oxidation, as well a…

Communicating interculturality in the workplace

2015

Variation of student engagement between different algebra tasks

2018

In this study, we analyse how 7th grade students’ engagement during small group work differed in two consecutive algebra lessons: in the first lesson students solved equa-tions and in the second lesson they created equations for other small groups to solve. Data was collected by videorecording the work of two groups in both lessons. Through directed content analysis, categories indicating student engagement were formed based on previous research and refined during analysis. The analysis revealed a change from individual engagement to collaborative engagement between lessons and an increase in many passive students’ engagement. Task characteristics which may affect the type and amount of eng…

Key challenges of new and small virtual team

2007

The purpose of this thesis is to study the factors must be noticed when building a new and small virtual team. These virtual teams are groups of people who work together without the boundaries of time or space using technology (Lipnack & Stamps 2000, 18). The main goal is to study in detail some of the common challenges faced when working with the small virtual teams, especially in the early stages of team development. With this study and the results of it, the reader is aware of the challenges of virtual teams and the differences and similarities between traditional and virtual teams. In addition the reader knows also some factors that must be noticed when a new small virtual team is suppo…