Search results for "Smoking"

Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample.

2021

Abstract Objective Tissue factor pathway inhibitor (TFPI) is a potent anticoagulant protein in the extrinsic coagulation pathway. In the present study, we aim to identify the cardiovascular determinants for total TFPI activity and its association with cardiovascular disease (CVD) and total mortality. Methods Total TFPI activity was assessed in a selection of the population-based Gutenberg Health Study (n = 5,000). Statistical analysis was performed to identify the determinants for total TFPI activity as well as the associations with CVD and mortality. Results Multivariable linear regression analysis identified smoking (β 0.095 [0.054–0.136]) as a positive determinant for total TFPI activity…

Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology …

2019

Aims The aim of this study was to determine whether the Joint European Societies guidelines on secondary cardiovascular prevention are followed in everyday practice. Design A cross-sectional ESC-EORP survey (EUROASPIRE V) at 131 centres in 81 regions in 27 countries. Methods Patients (<80 years old) with verified coronary artery events or interventions were interviewed and examined ≥6 months later. Results A total of 8261 patients (females 26%) were interviewed. Nineteen per cent smoked and 55% of them were persistent smokers, 38% were obese (body mass index ≥30 kg/m2), 59% were centrally obese (waist circumference: men ≥102 cm; women ≥88 cm) while 66% were physically active <30 min 5…

Electrochemical sensor for evaluating oxidative stress in airway epithelial cells

2021

Cigarette smoke exposure induces oxidative stress within the airways. Increased oxidative burden contributes to the pathogenesis of chronic lung disorders and is associated with aging and chronic inflammation. Airway epithelial cells highly contribute to Reactive Oxygen Species (ROS) generation within injured and inflamed lung tissues. Among ROS, hydrogen peroxide (H2O2) can be monitored in the extracellular space. Herein, we present an amperometric/voltammetric sensor based on gold nanoparticles and graphene oxide able to detect H2O2 with good sensitivity and selectivity. Using this sensor, H2O2 release was measured in conditioned medium from primary bronchial epithelial cells (PBEC), bron…

Can smoking have a positive effect on the course of certain diseases? A systematic review

2022

Background: Smoking cigarettes is a process during which many harmful substances are introduced into the lungs and the influence of these substances on the human body is not completely known. There are many diseases caused by smoking. Interestingly, there are also reports of positive consequences of smoking on some disorders. Aim of the study: The purpose of this article is to review the literature in regards to the diseases in which cigarettes might have a paradoxically beneficial effect — both on the onset and their course. We also want to focus on the mechanisms responsible for this impact. Material and Methods: Electronic searching of PubMed was performed. We analyzed articles published…

Prospective analysis of the influence of sport and educational factors on the prevalence and initiation of smoking in older adolescents from Croatia

2017

The prevalence of smoking among Croatian adolescents is alarmingly high, but no previous study has prospectively examined the sport- and academic-factors associated with smoking and smoking initiation. This study aimed to prospectively examine the associations between scholastic (educational) achievement and sport factors and smoking in 16- to 18-year-old adolescents. This two-year prospective cohort study included 644 adolescents who were 16 years of age at baseline (46% females). Baseline testing was implemented at the beginning of the 3rd year of high school (September 2014) when participants were 16 years old. Follow-up testing was completed at the end of the fourth year of high school,…

Trentino iedzīvotāju radzenes centrālās daļas endotēlijs

2017

Bakalaura darbs uzrakstīts angļu valodā uz 30 lappusēm. Tas satur 18 attēlus, 8 tabulas un atsauces uz 23 literatūras avotiem. Pētījuma mērķis bija novērtēt tādu faktoru kā smēķēšana un kontaktlēcu lietošana ietekme uz radzenes endotēlija fizioloģiju. Metode: 45 pacientiem (vecumā no 29 līdz 58 gadiem) veikta aptauja par smēķēšanas ieradumiem un kontaktlēcu lietošanu. Ikvienam tika novērtēts endotēlijs, trīs reizes mērot ar Takagi 700GL spraugas lampu un EndoKer programmu. Rezultāti: Darbā netika atrasta nozīmīga korelācija starp dzimumu un vecuma grupām attiecībā uz kādu no ietekmes faktoriem. Kā arī nebija nozīmīga atšķirība starp smēķētājiem, kontaktlēcu lietotājiem un normālo populāciju…

Spray-Dried Cytisine-Loaded Matrices: Development of Transbuccal Sustained-Release Tablets as a Promising Tool in Smoking Cessation Therapy

2022

Cytisine (CYT) has emerged as a promising molecule to treat nicotine addiction, since it acts as a partial agonist of nicotinic acetylcholine receptors. However, its unfavorable pharmacokinetic properties lead to multiple administrations per day, reducing the patient’s compliance and increasing the side effects. To overcome these drawbacks, CYT buccal administration is here proposed. Firstly, CYT stability in the buccal environment was assessed and its intrinsic ability to permeate/penetrate the tissue was determined by applying CYT solutions at increasing concentrations. Furthermore, a spray-drying method was selected and optimized as it is an eco-friendly, easily scalable and effective te…

Attitudes of Italian dental and dental hygiene students to tobacco-use cessation (TUC)

2008

Solving a model for the evolution of smoking habit in Spain with homotopy analysis method

2013

We obtain an approximated analytical solution for a dynamic model for the prevalence of the smoking habit in a constant population but with equal and different from zero birth and death rates. This model has been successfully used to explain the evolution of the smoking habit in Spain. By means of the Homotopy Analysis Method, we obtain an analytic expression in powers of time t which reproduces the correct solution for a certain range of time. To enlarge the domain of convergence we have applied the so-called optimal convergence-control parameter technique and the homotopy-Padé technique. We present and discuss graphical results for our solutions. ©

Lapsettomuutta kokeneiden tupakointi, alkoholinkäyttö ja paino Terveys 2011 tutkimuksessa

2017

TIIVISTELMÄ Vilanti, T. 2017. Lapsettomuutta kokeneiden tupakointi, alkoholinkäyttö ja paino Terveys 2011 tutkimuksessa. Liikuntatieteellinen tiedekunta, Jyväskylän yliopisto, Terveyskasvatuksen pro gradu -tutkielma Osa I 28 s., 2 liitettä. Osa II 19s. Tahaton lapsettomuus on yleistynyt sekä naisilla että miehillä niin Suomessa kuin maailmanlaajuisestikin. Monien elintapojen on todettu olevan yhteydessä hedelmällisyyteen. Heikentävästi siihen vaikuttavia ovat tupakointi, liiallinen alkoholin käyttö, epäterveellinen ruokavalio, sekä yli- tai alipaino. Tutkimuksen tarkoituksena oli tuottaa uutta tietoa lapsettomuuden ja siihen vaikuttavien elintapojen välisistä yhteyksistä yleensä sekä verrat…