Search results for "Smooth"

Lysed Erythrocyte Membranes Promote Vascular Calcification

2019

Background: Intraplaque hemorrhage promotes atherosclerosis progression, and erythrocytes may contribute to this process. In this study we examined the effects of red blood cells on smooth muscle cell mineralization and vascular calcification and the possible mechanisms involved. Methods: Erythrocytes were isolated from human and murine whole blood. Intact and lysed erythrocytes and their membrane fraction or specific erythrocyte components were examined in vitro using diverse calcification assays, ex vivo by using the murine aortic ring calcification model, and in vivo after murine erythrocyte membrane injection into neointimal lesions of hypercholesterolemic apolipoprotein E–deficient mi…

Coupled conditional backward sampling particle filter

2020

The conditional particle filter (CPF) is a promising algorithm for general hidden Markov model smoothing. Empirical evidence suggests that the variant of CPF with backward sampling (CBPF) performs well even with long time series. Previous theoretical results have not been able to demonstrate the improvement brought by backward sampling, whereas we provide rates showing that CBPF can remain effective with a fixed number of particles independent of the time horizon. Our result is based on analysis of a new coupling of two CBPFs, the coupled conditional backward sampling particle filter (CCBPF). We show that CCBPF has good stability properties in the sense that with fixed number of particles, …

Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristal…

2007

Cannabinoid-1 (CB1) receptor activation affects gastrointestinal propulsion in vivo. It was our aim to further characterize the involved myenteric mechanisms in vivo and in vitro. In CB1(-/-) mice and wild-type littermates we performed in vivo transit experiments by charcoal feeding and in vitro electrophysiological recordings in mouse small intestinal smooth muscle. Ascending neuronal contraction (ANC) following electrical field stimulation was studied in rat ileum in a partitioned organ bath separating the aboral stimulation site from the oral recording site. The knockout animals displayed an accelerated upper gastrointestinal transit compared to control animals. The CB1 receptor antagoni…

Quantification of LAI interannual anomalies by adjusting climatological patterns

2011

International audience; Scaling variations and shifts in the timing of seasonal phenology are central features of global change research. In this study, we propose a novel climatology fitting approach to quantify inter-annual anomalies in LAI seasonality. A consistent archive of daily LAI estimates was first derived from historical AVHRR satellite data for the 1981-2000 period over a globally representative sample of sites. The climatology values were then computed by averaging multi-year LAI profiles, gap filling and smoothing to eliminate possible high temporal frequency residual artifacts. The inter-annual variations in LAI were finally quantified by scaling and shifting the seasonal cli…

Smooth structures on algebraic surfaces with cyclic fundamental group

1988

PENERAPAN METODE SINGLE MOVING AVERAGE DAN EXSPONENTIAL SMOOTHING PADA USAHA ASRIE MODESTA

2020

This study  aims to (1) analyze the number of demands for batik products in the second period of 2018. (2) To analyze the most appropriate forecasting method. (3) To analyze the forecasting of the first period in 2019 using the selected forecasting method.
 This reseach uses primary data and secondary data with data collection techniques using interviews, observation, and documentation. The analysis used is Single Moving Averages and Exsponential Smoothing. 
 The results of research in forecasting demand for batik products in 2019 with the Single Moving Average method are 3,936 units with Mean Absolute Deviation (MAD) of 632.5 units and Mean Square Error (MSE) of 693,718 units. An…

The history of chemical enrichment in the intracluster medium from cosmological simulations

2017

The distribution of metals in the intracluster medium (ICM) of galaxy clusters provides valuable information on their formation and evolution, on the connection with the cosmic star formation and on the effects of different gas processes. By analyzing a sample of simulated galaxy clusters, we study the chemical enrichment of the ICM, its evolution, and its relation with the physical processes included in the simulation and with the thermal properties of the core. These simulations, consisting of re-simulations of 29 Lagrangian regions performed with an upgraded version of the SPH GADGET-3 code, have been run including two different sets of baryonic physics: one accounts for radiative coolin…

Pharmacological analysis of intrinsic neural control of rat duodenum motility in vitro

1988

Evaluation of the stromal vascular fraction of adipose tissue as the basis for a stem cell-based tissue-engineered vascular graft

2017

Abstract Objective One of the rate-limiting barriers within the field of vascular tissue engineering is the lengthy fabrication time associated with expanding appropriate cell types in culture. One particularly attractive cell type for this purpose is the adipose-derived mesenchymal stem cell (AD-MSC), which is abundant and easily harvested from liposuction procedures. Even this cell type has its drawbacks, however, including the required culture period for expansion, which could pose risks of cellular transformation or contamination. Eliminating culture entirely would be ideal to avoid these concerns. In this study, we used the raw population of cells obtained after digestion of human lipo…

Amplitude, Latency, and Peak Velocity in Accommodation and Disaccommodation Dynamics

2017

The aim of this work was to ascertain whether there are differences in amplitude, latency, and peak velocity of accommodation and disaccommodation responses when different analysis strategies are used to compute them, such as fitting different functions to the responses or for smoothing them prior to computing the parameters. Accommodation and disaccommodation responses from four subjects to pulse changes in demand were recorded by means of aberrometry. Three different strategies were followed to analyze such responses: fitting an exponential function to the experimental data; fitting a Boltzmann sigmoid function to the data; and smoothing the data. Amplitude, latency, and peak velocity of …