Search results for "SoMe"

showing 10 items of 5114 documents

Core Muscle Activity, Exercise Preference, and Perceived Exertion during Core Exercise with Elastic Resistance versus Machine

2015

Objectives. To investigate core muscle activity, exercise preferences, and perceived exertion during two selected core exercises performed with elastic resistance versus a conventional training machine.Methods. 17 untrained men aged 26–67 years participated in surface electromyography (EMG) measurements of five core muscles during torso-twists performed from left to right with elastic resistance and in the machine, respectively. The order of the exercises was randomized and each exercise consisted of 3 repetitions performed at a 10 RM load. EMG amplitude was normalized (nEMG) to maximum voluntary isometric contraction (MVC).Results. A higher right erector spinae activity in the elastic exer…

medicine.medical_specialtyCore (anatomy)Article Subjectmedicine.diagnostic_testbusiness.industrylcsh:RLeft external obliquelcsh:MedicinePerceived exertionIsometric exerciseElectromyographyErector spinae musclesPhysical therapyMedicinelcsh:QMuscle activitylcsh:ScienceGeneral Agricultural and Biological SciencesbusinessRight external obliqueResearch ArticleGeneral Environmental ScienceScientifica
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Cromakalim inhibits electrically-evoked [3H]acetylcholine release from a tube-preparation of the rat isolated trachea by an epithelium-dependent mech…

1993

Rat isolated tracheae were labelled by incubation with [3H]choline to measure the tritium efflux elicited by electrical stimulation of the extrinsic parasympathetic nerves in vitro. Stimulated tritium efflux reflects the neuronal release of newly synthesized acetylcholine; the effects of potassium channel openers on the stimulated tritium efflux were investigated. In tracheae opened longitudinally neither cromakalim nor its 3S,4R-enantiomer, BRL 38227, reduced the stimulated tritium efflux, whereas in intact tube-preparations cromakalim (0.01-1 mumol/l) mediated a concentration-dependent inhibition. The inhibitory effect of 1 mumol/l cromakalim was prevented by 0.1 mumol/l glibenclamide. Li…

medicine.medical_specialtyCromakalimPotassium ChannelsStimulationIn Vitro TechniquesEpitheliumGlibenclamidechemistry.chemical_compoundInternal medicinemedicineAnimalsBenzopyransPyrrolesPharmacologyStereoisomerismGeneral MedicinePotassium channelAcetylcholineRatsTracheaEndocrinologyMechanism of actionchemistrycardiovascular systemBiophysicsLiberationEffluxmedicine.symptomCromakalimAcetylcholinemedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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Preparation and karyotype analysis of mitotic chromosomes of the freshwater sponge Spongilla lacustris.

1993

The present study documents for the first time the karyotype and mitotic chromosomes of a sponge. For the studies the freshwater sponge Spongilla lacustris (Lin. 1758) was used. Its karyotype comprises nine different chromosome pairs ranging in size from 2.1 to < or = 0.7 microns. Changes in size and shape of the chromosomes during the progression of mitosis are documented both light and electron microscopically. The data reveal that the lowest multicellular eukaryotes, the sponges, have already reached a high level of evolution of the mitotic mechanism.

medicine.medical_specialtyCytogeneticsZoologyChromosomeMitosisKaryotypeDNABiologybiology.organism_classificationPoriferaSpongeMicroscopy ElectronSpongilla lacustrisKaryotypingGeneticsMicrochromosomemedicineAnimalsMitosisDevelopmental biologyGenetics (clinical)Chromosoma
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Safety of Topical Non-steroidal Anti-Inflammatory Drugs in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis

2019

Objective We aimed to assess the safety of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, placebo-controlled trials. Methods A comprehensive literature search was undertaken in the MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Scopus electronic databases. Randomized, double-blind, placebo-controlled, parallel-group trials that assessed adverse events (AEs) with topical NSAIDs in patients with OA were eligible for inclusion. Authors and/or study sponsors were contacted to obtain the full report of AEs. The primary outcomes were overall severe and serious AEs, as w…

medicine.medical_specialtyDICLOFENAC SODIUM GELDiclofenacDrug-Related Side Effects and Adverse ReactionsMedDRAVEHICLE TDT 064MEDLINEOsteoarthritisKNEE OSTEOARTHRITISAdministration CutaneousPlaceboLONG-TERM USE03 medical and health sciencesDOUBLE-BLIND0302 clinical medicinePharmacotherapyInternal medicineOsteoarthritisHumansMedicinePharmacology (medical)030212 general & internal medicineAdverse effectRandomized Controlled Trials as Topicbusiness.industryAnti-Inflammatory Agents Non-SteroidalTRANSFERSOME GELOdds ratiomedicine.diseaseEFFICACYRANDOMIZED CLINICAL-TRIALORAL CELECOXIBTreatment OutcomeMeta-analysisSystematic ReviewGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryTASK-FORCE
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A multicenter real‐life study on anticoagulant treatment with direct oral anticoagulants in patients with P h‐negative myeloproliferative neoplasms

2020

NA

medicine.medical_specialtyDOACbusiness.industrymyeloproliferative neoplasmvenous thromboembolismMEDLINEdirect oral anticoagulantAtrial fibrillationHematologymedicine.diseasePhiladelphia chromosomeClinical trialText miningAnticoagulant therapyInternal medicineMedicineLife studybusinessMyeloproliferative neoplasmatrial fibrillation.American Journal of Hematology
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The comparison of cold-water immersion and cold air therapy on maximal cycling performance and recovery markers following strength exercises

2016

This study examined the effects of cold-water immersion (CWI) and cold air therapy (CAT) on maximal cycling performance (i.e. anaerobic power) and markers of muscle damage following a strength training session. Twenty endurance-trained but strength-untrained male (n = 10) and female (n = 10) participants were randomised into either: CWI (15 min in 14 °C water to iliac crest) or CAT (15 min in 14 °C air) immediately following strength training (i.e. 3 sets of leg press, leg extensions and leg curls at 6 repetition maximum, respectively). Creatine kinase, muscle soreness and fatigue, isometric knee extensor and flexor torque and cycling anaerobic power were measured prior to, immediately afte…

medicine.medical_specialtyDelayed onset muscle sorenessStrength trainingHydrostatic pressurelcsh:MedicineIsometric exerciseGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineDelayed onset muscle sorenessmedicineCreatine kinaseta315Leg pressdelayed onset muscle sorenessbiologyPower outputcreatine kinasebusiness.industryGeneral Neurosciencelcsh:R030229 sport sciencesGeneral MedicineKinesiologySurgerypower outputAnesthesiabiology.proteinCreatine kinasevoimaharjoitteluStrength trainingmedicine.symptomGeneral Agricultural and Biological SciencesCyclingbusinessAnaerobic exercise030217 neurology & neurosurgeryPeerJ
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Pharmacokinetic evaluation of esomeprazole for the treatment of gastroesophageal reflux disease

2014

Proton pump inhibitors (PPIs) are widely used for the treatment of acid-related diseases such as gastroesophageal reflux disease (GERD). They are recommended by the American College of Gastroenterology for healing erosive esophagitis (EO) and as long-term treatment in patients with healed EO. The available PPIs differ somewhat in their pharmacokinetics and clinical properties, but whether these differences are of clinical relevance is a matter of debate. Some safety concerns have been raised with the use of PPIs, mostly an increased incidence of infectious diseases such as community-acquired pneumonia or Clostridium difficile diarrhea.This article explores the results of clinical studies on…

medicine.medical_specialtyDiseaseToxicologyGastroenterologyEsomeprazolePharmacokineticsInternal medicinemedicineEsophagitisHumansClinical significanceIntensive care medicinePharmacologybusiness.industryIncidenceIncidence (epidemiology)Public healthEsomeprazoleProton Pump InhibitorsStereoisomerismGeneral Medicinemedicine.diseasePneumoniaGastroesophageal RefluxGERDbusinessmedicine.drugExpert Opinion on Drug Metabolism &amp; Toxicology
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No paradox, no progress: inverse cancer comorbidity in people with other complex diseases.

2011

Salvador Martínez [et al.]. 5 p., 2 tables and references.

medicine.medical_specialtyDown syndromeAnorexia NervosaNeuregulin-1DiseaseComorbidity03 medical and health sciences0302 clinical medicineAlzheimer DiseaseNeoplasmsEpidemiologymedicineHumansGenetic Predisposition to DiseasePsychiatryComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbusiness.industryCancerParkinson Diseasemedicine.disease[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]Comorbidity3. Good healthOncologySchizophreniaAnorexia nervosa (differential diagnoses)SchizophreniaAlzheimer's diseaseDown Syndromebusiness030217 neurology & neurosurgeryChromosomes Human Pair 8The Lancet. Oncology
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The banding pattern of polytene chromosomes of Drosophila guanche compared with that of D. subobscura.

1987

A detailed map of the salivary gland chromosomes of Drosophila guanche is presented and compared to the standard gene arrangements of D. subobscura. Generally, the polytene chromosomc banding patterns of the two species show a high degrce of homology. Only Segment I of the sex chromosome (Chromosome A) shows marked differences. The banding pattern proposed for this segment in D. guanche could have originated from a cluster of overlapping inversions including A1 arrangement.

medicine.medical_specialtyDrosophila guanchePlant ScienceHomology (biology)Species SpecificityDrosophilidaeGeneticsmedicinePhotographyAnimalsGeneticsPolytene chromosomeSex ChromosomesbiologyCytogeneticsChromosomeChromosome MappingKaryotypeGeneral Medicinebiology.organism_classificationChromosome BandingInsect ScienceChromosome InversionGene ArrangementsAnimal Science and ZoologyDrosophilaGenetica
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Fatigue effects of marathon running on neuromuscular performance

2007

Nine experienced endurance runners performed individual marathon runs that involved several tests of neuromuscular performance before, during and after the marathon. The tests were performed with special force platform and dynamometer techniques. The results showed an overall decrease in performance from the marathon. The maximal sprint velocity decreased parabolically during the marathon, reaching the final value of 84% of the pre-marathon one. Similarly, the other test results after marathon indicated that maximal isometric knee extension torque was 78%, the performance in a special rebound test (drop jump) 84% and the 5-jump performance 92% of the pre-marathon values. These reductions we…

medicine.medical_specialtyDynamometerbusiness.industryPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseMuscle stiffnessStretch shortening cyclePhysical medicine and rehabilitationSprintJumpPhysical therapyMedicineOrthopedics and Sports MedicineForce platformGround reaction forcebusinesshuman activitiesScandinavian Journal of Medicine &amp; Science in Sports
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