Search results for "Soft tissue"

showing 10 items of 362 documents

A Difficult Case of Necrotizing Fasciitis Caused By Acinetobacter baumannii

2010

This study reports the case of a 55-year-old woman with diabetes with a necrotizing fasciitis of the right lower limb and the perineum, first admitted at the emergency department for septic shock with cardiac arrest, and later transferred to the department of surgery. Microbiological and histopathological examination confirmed the diagnosis of necrotizing fasciitis caused by Acinetobacter baumanii. A broad-spectrum antibiotic therapy was administered and later readjusted according to the results of microbiological culture. Intensive hemodynamic support was required. Wounds were dressed daily with a 3 percent boric acid solution and a silver sulfadiazine-impregnated dressing. An extensive s…

Acinetobacter baumanniiInsecticidesmedicine.medical_specialtyMicrobiological culturemedicine.medical_treatmentAcinetobacter Infections/diagnosis Acinetobacter Infections/drug therapy Acinetobacter Infections/microbiology* Acinetobacter baumannii/isolation &ampSettore MED/19 - Chirurgia PlasticaBoric AcidsmedicineHumansFasciitis NecrotizingFasciitisDebridementbiologybusiness.industrySeptic shockSoft Tissue Infectionspurification* Anti-Infective Agents Local/therapeutic use Boric Acids/therapeutic use Debridement Fasciitis Necrotizing/diagnosis Fasciitis Necrotizing/drug therapy Fasciitis Necrotizing/microbiology* Female Heart Arrest Humans Insecticides/therapeutic use Middle Aged Pseudomonas aeruginosa/isolation &ampGeneral MedicineEmergency departmentMiddle Agedbiology.organism_classificationmedicine.diseaseShock SepticSilver SulfadiazineHeart ArrestSurgeryAcinetobacter baumanniiPerineummedicine.anatomical_structureDebridementShock (circulatory)Pseudomonas aeruginosapurification Shock Septic Silver Sulfadiazine/therapeutic use Soft Tissue Infections/diagnosis Soft Tissue Infections/drug therapy Soft Tissue Infections/microbiologyAnti-Infective Agents LocalFemaleSurgerymedicine.symptombusinessAcinetobacter InfectionsThe International Journal of Lower Extremity Wounds
researchProduct

Congenital undifferentiated sarcoma associated to BCOR-CCNB3 gene fusion

2017

Small round cell sarcomas are aggressive bone and soft tissue tumors that predominantly affect children and young adults. A new group of sarcomas with a recurrent BCOR-CCNB3 gene fusion has been recently identified in previously unclassifiable small round cell sarcomas. BCOR-CCNB3 sarcomas share clinical and pathologic similarities with Ewing sarcoma, but show a stronger male predilection and less aggressiveness, as well as distinct gene expression profiling and pangenomic SNP array analyses. We report the unusual case of a congenital BCOR-CCNB3 retroperitoneal sarcoma in a female born at 34th gestational week, which was diagnosed in necropsy after 21hours of life. Immunohistochemical analy…

Adult0301 basic medicinePathologymedicine.medical_specialtyOncogene Proteins FusionTumor suppressor geneCD99Soft Tissue NeoplasmsCyclin BBiologyPathology and Forensic MedicineDiagnosis DifferentialFusion gene03 medical and health sciences0302 clinical medicineProto-Oncogene ProteinsBiomarkers TumormedicineHumansSMARCB1SarcomaCell Biologymedicine.diseaseRepressor ProteinsGene expression profiling030104 developmental biology030220 oncology & carcinogenesisCancer researchImmunohistochemistryFemaleSarcomaGene FusionSNP arrayPathology - Research and Practice
researchProduct

Evaluation of osteoblastic activity in extraction sockets treated with platelet-rich fibrin

2014

Objective: The aim of this study was to determine whether the use of platelet rich fibrin (PRF) improved the healing of extraction sockets. Study Design: A total of 20 patients with bilateral soft tissue impacted mandibular third molars were included in this study. The left and right third molars were extracted during the same session. Subsequently, the PRF membrane was randomly administered to one of the extraction sockets, whereas the contra lateral sockets were left without treatment. On postoperative 30. and 90. days, panoramic images and bone scintigrams were taken to evaluate the bone healing between PRF-treated and non-PRF-treated sockets. Also, periodontal evaluation was performed i…

AdultBlood PlateletsMaleMolarDentistryOdontologíaBone healingScintigraphyFibrinYoung AdultHumansMedicineTooth SocketGeneral DentistryDental alveolusFibrinWound HealingOsteoblastsbiologymedicine.diagnostic_testbusiness.industryResearchTooth ImpactedSoft tissue:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludPlatelet-rich fibrindigestive system diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASbiology.proteinFemaleSurgeryOral SurgerybusinessWound healing
researchProduct

Unravelling the heterogeneity of soft tissue and bone sarcoma patients’ health-related quality of life: a systematic literature review with focus on …

2020

Contains fulltext : 229532.pdf (Publisher’s version ) (Open Access) Patients with sarcoma experience many physical and psychological symptoms, adversely affecting their health-related quality of life (HRQoL). HRQoL assessment is challenging due to the diversity of the disease. This review aims to unravel the heterogeneity of HRQoL of patients with sarcoma with regard to tumour location and to summarise the used measures in research. English-language literature from four databases published between January 2000 and April 2019 was reviewed. Studies that described adult sarcoma HRQoL outcomes were included and classified according to primary sarcoma location. Eighty-seven articles met the incl…

AdultCancer Researchmedicine.medical_specialtyConstitutional symptomsPopulationbone sarcomaSoft Tissue NeoplasmsReviewBone Sarcomalcsh:RC254-282Quality of lifeInternal medicineSurveys and QuestionnairesMedicineHumans1506educationeducation.field_of_studyOsteosarcomabusiness.industrySoft tissue sarcomaSarcomamedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogenshumanitieshealth-related quality of lifeSystematic reviewOncologypatient-reported outcomessoft tissue sarcomaQuality of LifeSarcomabusinessPsychosocialRare cancers Radboud Institute for Health Sciences [Radboudumc 9]ESMO Open
researchProduct

Vertical Mandibular Alveolar Bone Distraction and Dental Implant Placement: A Case Report

2006

Abstract Extensive bone defects complicate the adequate placement of dental implants and the required angulation. In such cases, alveolar-ridge augmentation techniques such as guided bone regeneration, particulate or block grafting, and alveolar bone distraction are needed. The present study describes a case in which a large vertical bone defect in the anterior mandibular zone was corrected via vertical alveolar bone distraction. Six dental implants were posteriorly placed for implant-supported restoration of the mandible, with early implant loading. The clinical and radiologic control showed good implant and soft tissue conditions 12 months later.

AdultDental Stress Analysismedicine.medical_treatmentDenture Complete LowerOsteogenesis DistractionDentistryMandibleOsseointegrationHumansMedicineVestibuloplastyBone regenerationDental implantDental alveolusOrthodonticsbusiness.industryDental Implantation EndosseousMandibleSoft tissueVertical DimensionAlveolar Ridge AugmentationDistraction osteogenesisFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessJournal of Oral Implantology
researchProduct

"Only Spinal Fixation" as Surgical Treatment of Cervical Myelopathy Related to Ossified Posterior Longitudinal Ligament: Review of 52 Cases.

2020

Background Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition resulting in a progressive narrowing of the spinal canal and subsequent neurologic deficits. Although systemic and local factors in combination with genetic abnormality have been considered in its etiopathogenesis, OPLL remains a poorly understood pathology. Surgical management of OPLL and the choice of the most appropriate treatment are still controversial issues. Here the authors report a series of OPLL-affected patients treated by “only-fixation” technique. Methods Between June 2012 and June 2019, 52 patients having OPLL were treated by a surgical strategy involving only spinal fixation with…

AdultJoint InstabilityMalemedicine.medical_specialtyDecompressionArthrodesismedicine.medical_treatmentOssification of Posterior Longitudinal Ligament03 medical and health sciencesMyelopathyFixation (surgical)0302 clinical medicineSpinal instabilitymedicinePosterior longitudinal ligamentHumansSpinal canalFacetal fixationAtlantoaxial instabilityAgedPain MeasurementNeck Painbusiness.industrySoft tissueMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureSpinal FusionTreatment OutcomeAtlantoaxial instabilityPatient Satisfaction030220 oncology & carcinogenesisCervical VertebraeSurgeryFemaleNeurology (clinical)businessSpinal Cord Compression030217 neurology & neurosurgeryWorld neurosurgery
researchProduct

Prospective study of the 532 nm laser (KTP) versus diode laser 980 nm in the resection of hyperplastic lesions of the oral cavity

2018

Background The aim of this study is to evaluate the resection of hyperplastic lesions on the buccal mucosa comparing the 532nm laser (KTP), versus diode 980nm laser, considering pain, scarring, inflammation and drug consumption that occurred postoperatively with each lasers. Material and Methods A prospective study of consecutive series of 20 patients in two groups that presents hyperplastic lesions on the buccal mucosa. The choice of the KTP laser or diode 980nm laser for the surgery was made randomly. The power used was 1.5W in both groups in a continuous wave mode with a 320 μm optical fiber. Parameters of pain, scarring, inflammation and consumption of drugs were recorded by a Numerical…

AdultMaleAdolescentLasers Solid-StateOral cavityBuccal mucosaResectionlaw.inventionOral soft tissuesYoung Adult030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinelawHumansMedicineProspective StudiesProspective cohort studyGeneral DentistryAgedDiodeHyperplasiabusiness.industryResearchMouth Mucosa030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]LaserOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASKtp laserFemaleSurgeryLasers SemiconductorOral SurgerybusinessNuclear medicine
researchProduct

Mandibular connective tissue pedicle flaps in implant dentistry: report of three cases.

2007

Abstract An increase in soft tissues and alveolar bone in the anterior mandibular area between the canines is necessary to achieve a good esthetic result. The present article describes a technique for gaining bone volume and soft tissue to cover bone defects that would otherwise compromise the final result of prosthetic implant restoration in the anterior mandible. Three patients with anterior mandibular atrophy caused by loss of the mandibular incisors are presented. Particulate autologous bone grafting, the raising of a pediculate connective tissue flap to increase soft tissue, and implant placement were carried out simultaneously. After 2 years of follow-up, the implants were in good cli…

AdultMaleAlveolar Bone LossGingivaDentistryConnective tissueMandibleEsthetics DentalTransplantation AutologousSurgical FlapsAtrophyOsseointegrationmedicineHumansDental alveolusOrthodonticsDental ImplantsBone TransplantationImplant dentistrybusiness.industryMandibleSoft tissueAlveolar Ridge AugmentationMiddle Agedmedicine.diseaseIncisormedicine.anatomical_structureConnective TissueFemaleImplantOral SurgeryAtrophybusinessBone volumeFollow-Up StudiesThe Journal of oral implantology
researchProduct

Patterns of differentiation in extraosseous Ewing's sarcoma cells. An in vitro study.

1994

BACKGROUND In vitro, tissue culture-associated differentiation assays have facilitated the identification of multiple tumor-cell types. METHODS We have investigated the capability of differentiation of three extraosseous Ewing's sarcoma cell lines toward a neural and muscular direction by in vitro stimulation with dibutyryl cyclic adenosine-monophosphate (db cAMP) and 5-azacytidine, respectively. RESULTS Elongation of cytoplasmic processes and increase of neural markers chromogranin, S-100 protein, and glial fibrillary acidic protein were observed after db cAMP treatment of these lines and neurosecretory granules as well as myelin figures were demonstrated ultrastructurally. These results s…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyAdolescentCellular differentiationSoft Tissue NeoplasmsSarcoma EwingMyelinmedicineTumor Cells CulturedHumansMicroscopy Phase-ContrastbiologyGlial fibrillary acidic proteinNeural crestChromogranin AInfantCell Differentiationmedicine.diseaseImmunohistochemistryMicroscopy Electronmedicine.anatomical_structureOncologyBucladesineCell cultureAbdominal NeoplasmsCancer researchbiology.proteinAzacitidineImmunohistochemistryFemaleSarcomaCancer
researchProduct

[18F]5-fluoro-2-deoxyuridine-PET for imaging of malignant tumors and for measuring tissue proliferation

2003

The nucleoside 5-fluoro-2-deoxyuridine is a pyrimidine analogue accumulating in proliferative cells. We prospectively evaluated biodistribution of the PET tracer [(18)F]5-fluoro-2-deoxyuridine (FdUrd), its value for imaging malignant tumors, and its correlation to both [(18)F]2-fluoro-2-deoxyglucose (FDG)-PET findings and histological proliferation indices. In 11 previously untreated patients (5 lung carcinoma; 3 soft tissue sarcoma; 2 gastrointestinal carcinoma; 1 non-Hodgkin lymphoma [NHL]), mean doses of 290 MBq FdUrd and 390 MBq FDG were administered intravenously on subsequent days. Static PET scans were initiated 50-70 min after administration and the mean standardized uptake values (…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyLung NeoplasmsProliferation indexUrinary BladderKidneyBone and BonesPyrimidine analogueFluorodeoxyglucose F18NeoplasmsmedicineCarcinomaHumansTissue DistributionRadiology Nuclear Medicine and imagingProspective StudiesAgedGastrointestinal NeoplasmsNeoplasm StagingPharmacologymedicine.diagnostic_testbusiness.industryLymphoma Non-HodgkinSoft tissue sarcomaKidney metabolismSarcomaGeneral MedicineMiddle Agedmedicine.diseaseLymphomaKi-67 AntigenLiverOncologyPositron emission tomographyFemaleSarcomaRadiopharmaceuticalsbusinessNuclear medicineCell DivisionTomography Emission-Computed
researchProduct