Search results for "Sol"
showing 10 items of 23782 documents
Cell biology of canine parvovirus entry
2003
Sanna Suikkasen väitöskirjatyössä havaittiin, että koiran parvovirus tarvitsee solun tarjoamaa kuljetuskoneistoa edetäkseen sen sisällä ja happamia olosuhteita pystyäkseen lisääntymään. Tulokset antavat kehykset viruksen ja sen läheisten sukulaisten solunsisäisen reitin tarkemmalle tutkimukselle ja luovat pohjaa viruslääkkeiden suunnitteluun. Mielenkiintoa parvoviruksien tutkimukseen lisää tutkijan mielestä myös kiinnostus parvopartikkeleiden geeniterapiasovellutuksiin. Koiran parvovirus eriytyi kissan panleukopeniaviruksesta 1970-luvun lopulla ja levisi nopeasti ympäri maailmaa. Se aiheuttaa aikuisille koirille ankaraa ripulia ja pennuille tappavia sydänlihastulehduksia. Parvovirukset aihe…
Three Phages from a Boreal Lake during Ice Cover Infecting Xylophilus, Caulobacter, and Polaromonas Species
2023
Although the important role of microbes in freshwater is well understood, studies on phage–host systems in such environments during ice cover are completely lacking. Here, we describe the isolation and characterization of three new bacteriophages infecting Xylophilus sp., Caudobacter sp., and Polaromonas sp. from freshwater samples taken under the ice cover of Lake Konnevesi, Finland. Lumi, Kuura, and Tiera bacteriophages have tailed icosahedral virions and double-stranded DNA. Lumi is a siphophage with a genome of 80,496 bp, and Kuura and Tiera are podophages, and their genomes are 43,205 and 45,327 bp in length, resembling viruses in the class Caudoviricetes. Their host ranges were very l…
Quantitative microscopy reveals stepwise alteration of chromatin structure during herpesvirus infection
2019
During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm. We have shown previously that HSV-1 infection induces the formation of channels through the compacted peripheral chromatin. Here, we used three-dimensional confocal and expansion microscopy, soft X-ray tomography, electron microscopy, and random walk simulations to analyze the kinetics of host chromatin redistribution and capsid localization relative to their egress site at the nuclear envelope. Our data demonstrated a gradual increase in chromatin marginalization, and the kinetics of chromatin smoothening arou…
A single tube PCR assay for detecting viruses and their recombinants that cause tomato yellow leaf curl disease in Mediterranean basin
2007
Tomato yellow leaf curl disease (TYLCD) is well known in Mediterranean countries, where it has been causing severe losses in tomato crops for decades. Until recently, two viruses (with several isolates) in the genus Begomovirus, family Geminiviridae, have been associated with the epidemics: Tomato yellow leaf curl virus (TYLCV) and Tomato yellow leaf curl Sardinia virus (TYLCSV). However, recombinants between these, such as Tomato yellow leaf curl Malaga virus (TYLCMalV), are spreading, and new methods for detecting all viruses present in the region are needed. By considering all DNA sequences available of viruses causing TYLCD in the Mediterranean basin, a PCR/RFLP protocol was developed t…
On the Dynamics of Fractional Visco-Elastic Beams
2012
With increasing advanced manufacturing process, visco-elastic materials are very attractive for mitigation of vibrations, provided that you may have advanced studies for capturing the realistic behavior of such materials. Experimental verification of the visco-elastic behavior is limited to some well-known low order models as the Maxwell or Kelvin models. However, both models are not sufficient to model the visco-elastic behavior of real materials, since only the Maxwell type can capture the relaxation tests and the Kelvin the creep tests, respectively. Very recently, it has been stressed that the most suitable model for capturing the visco-elastic behavior is the spring-pot, characterized …
Game-Theoretic Approach to Hölder Regularity for PDEs Involving Eigenvalues of the Hessian
2021
AbstractWe prove a local Hölder estimate for any exponent $0<\delta <\frac {1}{2}$ 0 < δ < 1 2 for solutions of the dynamic programming principle $$ \begin{array}{@{}rcl@{}} u^{\varepsilon} (x) = \sum\limits_{j=1}^{n} \alpha_{j} \underset{\dim(S)=j}{\inf} \underset{|v|=1}{\underset{v\in S}{\sup}} \frac{u^{\varepsilon} (x + \varepsilon v) + u^{\varepsilon} (x - \varepsilon v)}{2} \end{array} $$ u ε ( x ) = ∑ j = 1 n α j inf dim ( S ) = j sup v ∈ S | v | = 1 u ε ( x + ε v ) + u ε ( x − ε v ) 2 with α1,αn > 0 and α2,⋯ ,αn− 1 ≥ 0. The proof is based on a new coupling idea from game theory. As an application, we get the same regularity estimate for viscosity solutions of the PDE $…
Equivalence of viscosity and weak solutions for a $p$-parabolic equation
2019
AbstractWe study the relationship of viscosity and weak solutions to the equation $$\begin{aligned} \smash {\partial _{t}u-\varDelta _{p}u=f(Du)}, \end{aligned}$$ ∂ t u - Δ p u = f ( D u ) , where $$p>1$$ p > 1 and $$f\in C({\mathbb {R}}^{N})$$ f ∈ C ( R N ) satisfies suitable assumptions. Our main result is that bounded viscosity supersolutions coincide with bounded lower semicontinuous weak supersolutions. Moreover, we prove the lower semicontinuity of weak supersolutions when $$p\ge 2$$ p ≥ 2 .
Hölder gradient regularity for the inhomogeneous normalized p(x)-Laplace equation
2022
We prove the local gradient Hölder regularity of viscosity solutions to the inhomogeneous normalized p(x)-Laplace equation −Δp(x)Nu=f(x), where p is Lipschitz continuous, infp>1, and f is continuous and bounded. peerReviewed
Hölder regularity for the gradient of the inhomogeneous parabolic normalized p-Laplacian
2018
In this paper, we study an evolution equation involving the normalized [Formula: see text]-Laplacian and a bounded continuous source term. The normalized [Formula: see text]-Laplacian is in non-divergence form and arises for example from stochastic tug-of-war games with noise. We prove local [Formula: see text] regularity for the spatial gradient of the viscosity solutions. The proof is based on an improvement of flatness and proceeds by iteration.
Regularity for nonlinear stochastic games
2015
We establish regularity for functions satisfying a dynamic programming equation, which may arise for example from stochastic games or discretization schemes. Our results can also be utilized in obtaining regularity and existence results for the corresponding partial differential equations. peerReviewed