Search results for "Sorting"

A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum

2010

Gene m164 of murine cytomegalovirus belongs to the large group of 'private' genes that show no homology to those of other cytomegalovirus species and are thought to represent 'host adaptation' genes involved in virus-host interaction. Previous interest in the m164 gene product was based on the presence of an immunodominant CD8 T-cell epitope presented at the surface of infected cells, despite interference by viral immune-evasion proteins. Here, we provide data to reveal that the m164 gene product shows unusual features in its cell biology. A novel strategy of mass-spectrometric analysis was employed to map the N terminus of the mature protein, 107 aa downstream of the start site of the pred…

Oligodendrocyte and Schwann Cell Identification Methods

2009

Oligodendrocytes and Schwann cells were first identified using light and electron microscopy of tissue. With the definition of proteins and lipids specific to these cells, antigen localization or in situ hybridization of the mRNA has facilitated identification in vivo and in vitro. Transgenic and ‘knockin’ mice have been generated in which cells expressing a specific promoter are fluorescently labeled. This permits isolation of the cells by fluorescence-activated cell sorting and the study of the labeled cells in situ by techniques such as electrophysiology. Transgenic zebra fish, in which the glial cells are similarly labeled, facilitate studies of these cells in the living animal.

2018

Introduction Introduction: eating disorders (ED) such as anorexia nervosa (AN) or bulimia nervosa (BN), as well as obesity (OB), are related to emotional and neuropsychological impairments on measures of cognitive flexibility, central coherence or decision making. However, little is known about the association among emotional regulation, neuropsychological variables and affect. Objectives: to analyze whether neuropsychological and affect variables can predict emotional regulation in ED and in OB. Methods: thirty females with restricting ED (restricting AN) were assessed, 18 with purging ED (purging AN and BN), 33 with OB and 39 healthy controls matched for intelligence. The Wisconsin Card S…

Multi‐criteria decision‐making approach for modular enterprise resource planning sorting problems

2021

[EN] Implementing Enterprise Resource Planning (ERP) systems is currently recognized as a best practice with wide associated possibilities of business improvement for companies. Integrating these kinds of systems with business processes in the most efficient way requires to endeavour as much as possible simplifications for final users, which can be pursued by optimizing crucial software characteristics. The present article proposes a novel Multi-Criteria Decision-Making (MCDM) approach to deal with such an issue. Specifically, the ELECTRE (ELimination Et Choix Traduisant la REalite) TRI technique is suggested to assign ERP modules into predefined and ordered categories according to maintain…

A multi-objective optimal allocation of treated wastewater in urban areas using leader-follower game

2020

Abstract This study proposes a new method for optimal allocation of Treated Wastewater (TW), in which different stakeholders, their social position in decision-making, and priority of objectives were attended using the leader-follower game theory. The suggested methodology was applied in a case study in the eastern part of Tehran province in Iran, where the Water and Sewage Department is considered the leader and four TW dependent districts are the followers in the game model. The leader appropriates a certain TW quantity to the system, and the followers compete for the allocated resources in the face of various physical and sociopolitical constraints. The Nash-Harsanyi production function …

Crowded comparison operators for constraints handling in NSGA-II for optimal design of the compensation system in electrical distribution networks

2006

This paper proposes an improvement of an efficient multiobjective optimization algorithm, Non-dominated Sorting Genetic Algorithm II, NSGA-II, that has been here applied to solve the problem of optimal capacitors placement in distribution systems. The studied improvement involves the Crowded Comparison Operator and modifies it in order to handle several constraints. The problem of optimal location and sizing of capacitor banks for losses reduction and voltage profile flattening in medium voltage (MV) automated distribution systems is a difficult combinatorial constrained optimization problem which is deeply studied in literature. In this paper, the efficiency of the proposed Crowded Compari…

Integer programming models for the pre-marshalling problem

2019

[EN] The performance of shipping companies greatly depends on reduced berthing times. The trend towards bigger ships and shorter berthing times places severe stress on container terminals, which cannot simply increase the available cranes indefinitely. Therefore, the focus is on optimizing existing resources. An effective way of speeding up the loading/unloading operations of ships at the container terminal is to use the idle time before the arrival of a ship for sorting the stored containers in advance. The pre-marshalling problem consists in rearranging the containers placed in a bay in the order in which they will be required later, looking for a sequence with the minimum number of moves…

Personality, occupational sorting and routine work

2020

PurposeA prominent labour market feature in recent decades has been the increase in abstract and service jobs, while the demand for routine work has declined. This article examines whether the components of Type A behaviour predict workers' selection into non-routine abstract, non-routine service and routine jobs.Design/methodology/approachBuilding on the work by Barrick et al. (2013), this article first presents how the theory of purposeful work behaviour can be used to explain how individuals with different levels of Type A components sort into abstract, service and routine jobs. Then, using longitudinal data, it examines whether the components of Type A behaviour predict occupational sor…

Reconstitution du squelette d'astérides fossiles à partir d'ossicules isolés : intérêt taxinomique et phylogénétique

1999

Abstract Dissociated ossicles of asteroids are frequent in neritic sediments. Until now, this material was mainly used in the identification of species. A new method, associating a morphological analysis and counting of plates, allows the architecture of the skeleton and the shape of the body to be reconstructed. This method provides new elements for taxonomic and phylogenetic comparisons. It also provides indications on the adaptation of the asteroids to their environment. In geological beds, frequencies of the different kinds of plates will allow qualification of bioerosion and taphonomic sorting.

MicroRNA and Cardiac Stem Cell Therapy

2012

Cardiac Progenitor Cells (CPCs) are multipotent cells of the myocardium. They are located inside niches of the heart muscle, can be isolated, characterized and used for cardiac regeneration in stem cell therapy. Actually, CPCs may be isolated by tissue digestion with or without cell sorting, but it is difficult to achieve the maximum level of differentiation when these cells are implanted into a damaged myocardium. The knowledge recently acquired on small molecules of non-coding RNAs, microRNA (miRNA), may improve the use of these cells in stem cell therapy. In fact, these small molecules may be attached to devices or adminstered as they are or in combination with nanoparticles in order to …