Search results for "Souris"
showing 10 items of 25 documents
Impact of obesity on the oro-sensory detection of dietary lipids in mice and humans
2013
Gustation is an essential parameter in the oro-sensory detection of dietary lipids. In mice and most likely in humans, the binding of long-chain fatty acids to the CD36 receptor plays a major role in this oral fat detection. Gustation is involved in the food choice (fat sensitivity) as well as in the preparation of the body to the fat inflow. This oral lipid sensing is highly regulated. As obesity seems to be responsible for an alteration of the basic tastes detection, the aim of this thesis was to investigate whether obesity can impair the oral lipid detection in both mice and humans. In humans, our data show that there is an alteration of the oral fat detection in some obese subjects who …
Vers un lien entre plasticité du cerveau et satiété
2021
Vous venez de terminer un bon repas et vous vous sentez repu ?Des chercheurs (1) viennent de comprendre des mécanismes qui, dans votre cerveau, ont contribué à cet état. Il s’agit d’une cascade de réactions déclenchée par l’élévation du taux de glucose dans le sang.Dans une nouvelle étude menée chez la souris, l’équipe dirigée par Alexandre Benani, chercheur CNRS au Centre des Sciences du Goût et de l’Alimentation (2) montre que les circuits de neurones qui freinent la prise alimentaire sont activés après un repas et cette activation implique des mouvements de cellules dans le cerveau.Cette étude a été publiée dans Cell Reports le 3 mars 2020.Lire le communiqué de presse : https://bit.ly/3j…
Rétine et lipides : de l'analyse à la physiopathologie
2016
Revue; Rétine et lipides : de l'analyse à la physiopathologie. Colloque du Collège National de Biochimie-Biologie Moléculaire Médicale (CNBBMM)
Mouse olfactory sensory neurons' plasticity induced by postnatal odorant exposure: anatomical, molecular and physiological consequences
2012
Mouse olfactory sensory neurons' plasticity induced by postnatal odorant exposure: anatomical, molecular and physiological consequences. 8. FENS forum of neuroscience
Les comportements préalables à la prise lactée chez le souriceau : caractérisation de sécrétions maternelles réactogènes et implication de l'expérien…
2012
Birth is one of the most delicate periods mammalian infants have to deal with. Newborns have then to adapt physiologically and behaviorally to the aerial environment, and one of their first challenges is to ingest colostrum and milk. It is paradoxical that the survival of pups is conditioned by the success of this first suckling, and that we have so little understanding of the stimuli that underlie and promote it. Thus, the present work aims to contribute to answer how immature and naïve newborns do manage to orient to a nipple, to grasp it, and to suckle efficiently? This general issue will be addressed in the mouse in focusing on: i) the nature of the chemical substrates that newborn mice…
Olfactory neurons plasticity : environment effects during development
2012
In order to investigate the consequences of postnatal odorant exposure on a specific population of olfactory sensory neurons (OSNs), we have taken the following experimental approach. MOR23-GFP mice were daily exposed to Lyral for 21 days starting at birth and three lines of investigations were carried out. Using anatomical analysis we observe that the density of OSNs expressing MOR23 decreases after odorant exposure. This decrease concerns primarily matures OSN (MOR23-OMP+). In order to study molecular changes within individual OSNs, mRNA levels for olfactory signaling pathway components were quantitatively analyzed using qPCR on GFP-labeled neurons (7 per mouse). mRNAs for CNGA2, PDE1C an…
Olfactory neurons plasticity : environment effects during development
2012
In order to investigate the consequences of postnatal odorant exposure on a specific population of olfactory sensory neurons (OSNs), we have taken the following experimental approach. MOR23-GFP mice were daily exposed to Lyral for 21 days starting at birth and three lines of investigations were carried out. Using anatomical analysis we observe that the density of OSNs expressing MOR23 decreases after odorant exposure. This decrease concerns primarily matures OSN (MOR23-OMP+). In order to study molecular changes within individual OSNs, mRNA levels for olfactory signaling pathway components were quantitatively analyzed using qPCR on GFP-labeled neurons (7 per mouse). mRNAs for CNGA2, PDE1C an…
Etapes précoces des candidoses systémiques : Etude du rôle des cellules M au cours de l'interaction de Candida albicans avec la muqueuse digestive
2015
Interactive devices for faster access to information: navigation system for digital documents
2008
This article presents a step towards the inclusion of a preview control with established tactile interactive devices, such as the computer mouse and touch pad. It describes the origins of the device and its likely advantages in terms of ease of use and faster data retrieval as, for example, when a page previously consulted needs to be accessed again. The article limits itself to the contribution made by the device towards the consultation of digital documents, in particular on Internet sites. The device presented below makes it possible to leaf through a whole digital document from one and the same screen without mouse clicks. It can be used directly, by means of a command integrated into t…
Documents numériques : vers de nouveaux dispositifs d'interaction
2005
5 pages, publication des communications sur le site de la conférence; National audience; Actuellement les modes d'interaction avec les documents numériques visent à diminuer les contraintes d'espace et de temps avec notamment des dispositifs d'informations locales et une capacité de consultation étendue depuis un point central. On retrouve en cela les résultats d'études plus anciennes en ergonomie sur les tableaux de contrôle de processus (trafic ferroviaire, centrales nucléaires, tableaux de contrôles d'usines chimiques etc.) Une deuxième tendance, plus difficile à mettre en œuvre, consiste à permettre plusieurs types de présentation d'un document, que l'utilisateur peut adapter en fonctio…