Search results for "SpA"

showing 10 items of 34087 documents

Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium.

2017

Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia. The present study was conducted in order to evaluate neuronal effects of SUG alone and in combination with both ROC and VEC. Using MTT, CASP-3 activity and Western-blot we determined the toxicity of SUG, ROC or VEC in neurons in primary culture. SUG induces apoptosis/necrosis in neurons in primary culture and increases cytochrome C (CytC), apoptosis-inducing factor (AIF), Smac/Diablo and Caspase 3 (CASP-3) protein expression. Our results also demonstrated that both ROC and VEC prevent these…

vecuroniumNecrosisEstrès oxidatiuPrimary Cell CulturerocuroniumCaspase 3NeuronesPharmacologySugammadexSugammadex03 medical and health sciences0302 clinical medicine030202 anesthesiologymedicineAnimalsHumansAndrostanolsRocuroniumCell damageNeuronsVecuronium BromideDose-Response Relationship DrugCaspase 3business.industryapoptosis.Apoptosis Inducing FactorCytochromes c030208 emergency & critical care medicineGeneral Medicinemedicine.diseaseneuronRatsDrug Combinationsmedicine.anatomical_structureGene Expression RegulationApoptosisToxicityNeuronNeuromuscular Blocking Agentsmedicine.symptombusinessResearch Papergamma-Cyclodextrinsmedicine.drug
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Regional metacommunities in two coastal systems: spatial structure and drivers of plant assemblages

2014

Aim Biogeographical patterns in metacommunities are still poorly understood, and different processes are expected to occur in different habitats. We analysed the regional plant metacommunities of coastal habitats to test whether (1) the influence of space and climate differs between two habitats differentiated along the seashore–inland gradient, and (2) regional variation in species composition of these habitats can be ascribed to different metacommunity paradigms. Location The entire coast of the Iberian Peninsula, south-western Europe. Methods We collected data on the plant species composition of coastal sites on sand dunes across 3000 km of coastline. The sites were classified into two h…

vegetation databasesMetacommunityMediterranean climateDistance decaydune habitatsmetacommunityEcologyCommunity assemblyEcologydistance decaySpecies sortingenvironmental filtering15. Life on landdispersal limitationSand dune stabilizationGeographyHabitatSpatial ecologyOrdination14. Life underwaterspecies sortingCommunity assembly dispersal limitation distance decay dune habitats environmental filtering Iberian Peninsula metacommunity species sorting vegetation databasesEcology Evolution Behavior and SystematicsIberian PeninsulaJournal of Biogeography
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If Only They Knew: Audience Expectations and Actual Sourcing Practices in Online Journalism

2019

This article answers the question “Are the sourcing practices in Finnish online journalism trustworthy?” Here, trustworthiness is operationalized as the fulfillment of audience expectations towards sourcing practices. To this end, expectations of young Finnish adults (aged 18–28) were compared to the observed practices of Finnish online journalists. A total of 36 news items (from 12 journalists working in three newsrooms, published in 2013 and 2017) were analyzed. The analysis indicates that online journalists’ sourcing practices largely do not conform to this audience segment's expectations. Namely, the audience expects more comprehensive investigation and thorough verification than what i…

verkkojournalismiOnline journalismOperationalizationComputingMilieux_THECOMPUTINGPROFESSIONbusiness.industryCommunication05 social sciencessourcing050801 communication & media studiesPublic relationstrustworthinessTransparency (behavior)0506 political scienceläpinäkyvyysverifiointi0508 media and communicationsTrustworthinessluottamusData_GENERALverifikaatio050602 political science & public administrationBusinessluotettavuusJournalism Practice
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The effects of two-way communication and chat service usage on consumer attitudes in the e-commerce retailing sector

2018

In e-commerce retailing (e-retailing), where competitors are only one click away and prices are easy to compare, providing superior customer service and reciprocal communication via a company’s website are important aspects of attracting and retaining customers. One increasingly popular solution to improve customer service is a “live chat” interface that allows consumers to have real-time conversations online with customer service agents. As the literature on the impacts of real-time communication via live chat is currently very limited, this study develops and tests a model that demonstrates the moderating effects of a chat service on the relationship between two-way communication (i.e., a…

verkkokauppa (verkkoliiketoiminta)Economics and EconometricsasiakaspalveluE-commerceInteractivityManagement of Technology and Innovation0502 economics and businesse-commerceverkkojutteluBusiness and International Managementcomputer-mediated communicationMarketingService (business)business.industry05 social sciencesAdvertisingCompetitor analysisComputer Science ApplicationsCore (game theory)live chatonline retailing050211 marketingCustomer satisfactionTwo-way communicationComputer-mediated communicationverkkokaupat (WWW-sivustot)business050203 business & managementElectronic Markets
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Chatbot-teknologia : sähköinen kaupankäynti ja asiakaspalvelu

2015

Tutkimusorganisaatio Gartnerin tutkimuksissa on arvioitu, että vuonna 2020 yli 85 % asiakaspalvelutapahtumista hoituu ilman ihmisen avustusta, jolloin esimerkiksi Yhdysvaltojen 18 miljoonasta myyjästä on jäljellä enää vain noin 4 miljoonaa. Väitettä tukee myös virtuaalisten assistenttien tekemä myynti, mikä on kasvanut 2010-luvulla vuosittain 50 %. Tässä tutkielmassa käsitellään tekoälyä hyödyntävää virtuaalista assistenttia, eli chatbottia. Tutkielman tavoitteena on tutkia ja vertailla jo olemassa olevia toteutuksia sekä laatia kirjallisuuskatsauksena teoreettinen vaatimusmäärittely toimivan chatbotin toteutukseen verkkokauppojen asiakaspalvelussa. Lisäksi tutkie…

verkkokauppaostopäätösprosessiasiakaspalveluchatbottekoäly
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Transformative technologies, spatial changes : essays on mobile phones and the Internet

2009

Sakari Taipale tarkastelee väitöskirjassaan sitä, kuinka matkapuhelimen ja internetin käyttö vaikuttaa sosiaalisten tilojen muodostumiseen.Uudet informaatio- ja kommunikaatioteknologiat ovat monipuolistaneet sosiaalisen vuorovaikutuksen muotoja. Matkapuhelimen ja internetin avulla sosiaalisia tiloja, erilaisia toimijoiden yhteenliittymiä, voidaan luoda tietoverkoissa ilman toisten ihmisten fyysistä läsnäoloa. Tämän seurauksena sosiaalisen tilan kahden keskeisen osatekijän, rajojen ja tarkoituksen, välinen suhde on muuttunut. Rajat näyttävät menettäneen suhteellista merkitystään sosiaalisen tilan koossapysyvyyden kannalta, kun taas tilan tarkoituksen merkitys on vahvistunut.- Verkkoympäristö…

verkostotInternetvuorovaikutussocial spacesocial mediaconflictverkostoituminensosiaalinen mediaglobalisaatiososiaaliset ongelmatkonfliktittietotekniikkaristiriidatsosiaaliset suhteetnetworktilatransformative technologytietoverkotmobile phonesmatkapuhelimet
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The Networked Utilisation of Satellite Images and Geospatial Technology in Journalism

2022

Satellite technology has become increasingly affordable and accessible in the past few decades. This has enabled many newsrooms to engage with genuinely remote journalism. This chapter explores the networked nature of satellite journalism and investigates its inclusion of experts and citizens outside newsrooms. Satellite journalism uses satellite-borne technology either as a (1) part of storytelling or (2) source of information. Academic research on the topic is scarce, so this chapter builds a base of knowledge on the contemporary practices, limitations and ethics—as well as directions of future development—of satellite journalism. By interviewing six journalists and one earth observation …

verkostotgeospatial technologypaikkatiedotnetworked utilisationjournalismijournalismsatellite imagessatelliittikuvat
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Eläkeläisten muuttoaikeet ja muuttaminen : vertaileva tutkimus viiden hyvinvointivaltiomallimaan kesken

2012

vertailueläkeläisetkotieläkeläinenEspanjaasuminenhyvinvointiregiimiSaksahyvinvointivaltiomuuttoSuomiBulgariaIso-Britanniamuuttaminen
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Valeria Tatano e AA. VV. Oltre la trasparenza.

2012

Recensione del testo di VALERIA TATANO (CURATORE), Oltre la trasparenza. Riflessioni sull’impiego del vetro in architettura, Officina, Roma 2008. La storia del vetro in edilizia coincide con la ricerca della trasparenza: grazie al vetro la luce può entrare negli ambienti che, al tempo stesso, sono protetti dagli agenti atmosferici. Negli ultimi anni, con l’evoluzione tecnologica, abbiamo assistito a una rivoluzione delle possibilità di impiego di tale materiale. Il testo Oltre la trasparenza offre uno scenario completo sui possibili usi innovativi del vetro nell’architettura contemporanea; obiettivo dell’articolo è quello di evidenziare i caratteri essenziali di tale evoluzione.

vetro trasparenza evoluzioneSettore ICAR/12 - Tecnologia Dell'Architettura
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Vettori polimerici della poliaspartammide coniugati a bisfosfonati per il direzionamento di farmaci alle ossa.

2011

vettori polimerici poliaspartammide ossa.Settore CHIM/09 - Farmaceutico Tecnologico Applicativo
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