Search results for "Sparta"
showing 10 items of 301 documents
Turisti a Sparta. Il passato che non torna e l’invenzione della tradizione
2010
Un elemento che sembra concorrere in misura determinante alla definizione del turismo come prassi socioculturale diffusa è la tensione tra l’aspettativa della dimensione esotica e straniante da un lato, e dall’altro la tendenza all’inglobamento “autoidentitario”. Questa definizione consente di riflettere sui due livelli qui in gioco: lo spostamento e l’identità. La vulgata che fa iniziare nel XVII secolo le prime tracce di pratiche turistiche si scontra con testimonianze rilevanti su pratiche comparabili nel mondo antico. Già Platone (Leggi XII 949-950) teorizza l’utilità filosofica del “turismo” intellettuale. Il caso più interessante è però quello del “turismo” culturale a Sparta, divenut…
Las cuatro muertes de Cleonice: poder, sexo, violencia y fantasmas
2019
Greek tradition links the death of regent Pausanias of Sparta with ghosts. In this paper, we focus on the well-known episode that revolves around Pausanias himself and a Byzantine maiden and is transmitted by Aristodemus, Plutarch and Pausanias Periegetes. The multiplicity of versions demands a comparative analysis, which we carry out taking into account the three spaces where the narrative action takes place (civic, intimate and ritual spaces). Results indicate a concordance between Plutarch and Pausanias Periegetes, as well as a dissonance between them and Aristodemus. This difference especially affects the narrative treatment of the maiden, a ghost properly so-called in Plutarch and Paus…
Co-activation of VEGF and NMDA receptors promotes synaptic targeting of AMPA receptors
2016
A critical role for VEGF and VEGFR2 in NMDA receptor synaptic function and fear-related behavior
2016
Vascular endothelial growth factor (VEGF) is known to be required for the action of antidepressant therapies but its impact on brain synaptic function is poorly characterized. Using a combination of electrophysiological, single-molecule imaging and conditional transgenic approaches, we identified the molecular basis of the VEGF effect on synaptic transmission and plasticity. VEGF increases the postsynaptic responses mediated by the N-methyl-D-aspartate type of glutamate receptors (GluNRs) in hippocampal neurons. This is concurrent with the formation of new synapses and with the synaptic recruitment of GluNR expressing the GluN2B subunit (GluNR-2B). VEGF induces a rapid redistribution of Glu…
Electrophysiological and morphological properties of Cajal–Retzius cells with different ontogenetic origins
2010
International audience; The different origins of Cajal-Retzius cells (CRc) as well as their diverse molecular profile suggest that this cell type may represent different neuronal subpopulations. In order to investigate whether CRc from different origins show distinct functional or morphological characteristics we used transgenic Dbx1(cre);ROSA26(YFP) mice in which two subpopulations of CRc, originating from the septum and ventral pallium (VP) at the pallial-subpallial border (PSB), were permanently labeled by yellow fluorescent protein (YFP) expression. Electrophysiological properties of YFP(+) and YFP(-) CRc were investigated by whole-cell patch-clamp recordings, while a thorough somatoden…
Le sucre dans tous ses états - Sucre et enfance : comment agir ?
2013
Photocrosslinking of dextran and polyaspartamide derivatives: a combination suitable for colon-specific drug delivery.
2007
Abstract The aim of this study was to prepare and characterize novel hydrogels with polysaccharide–polyaminoacid structure, able to undergo an enzymatic hydrolysis in the colon and potentially useful for treating inflammatory bowel diseases (IBD). Starting materials were methacrylated dextran (DEX-MA) and methacrylated α,β-poly(N-2-hydroxyethyl)- dl -aspartamide (PHM). These polymers were photocrosslinked by exposure of their aqueous solutions at 313 nm without photoinitiators. Different samples, shaped as microparticles, were obtained as a function of polymer concentration and irradiation time. FT-IR analysis confirmed the occurrence of a co-crosslinking between DEX-MA and PHM in all exper…
Reduced brain N-acetyl-aspartate in frontal lobes suggests neuronal loss in patients with amyotrophic lateral sclerosis
1996
International audience; Abstract: We performed proton magnetic resonance spectroscopy (IH-MRS) in three patients with amyotrophic lateral sclerosis (ALS) to evaluate the distribution and extent of cortical neuronal damage as demonstrated by decreased N-acetyl-aspartate (NAA) levels. We examined primary motor (precentral gyrus) and parietal neocortical (superior parietal gyrus) regions. ALS was defined with lower and upper motor neuron signs. Compared with matched healthy controls, ALS patients had a significant decrease in NAA levels in the primary motor cortex (p<0.001) compared with parietal regions and homologous regions in healthy controls. Two clinical applications can be extracted: fi…