Search results for "Specialties"

showing 10 items of 49 documents

Random allogeneic blood transfusion in pigs: characterisation of a novel experimental model.

2019

BackgroundOrgan cross-talk describes interactions between a primary affected organ and a secondarily injured remote organ, particularly in lung-brain interactions. A common theory is the systemic distribution of inflammatory mediators that are released by the affected organ and transferred through the bloodstream. The present study characterises the baseline immunogenic effects of a novel experimental model of random allogeneic blood transfusion in pigs designed to analyse the role of the bloodstream in organ cross-talk.MethodsAfter approval of the State and Institutional Animal Care Committee, 20 anesthetized pig were randomized in a donor and an acceptor (eachn = 8): the acceptor animals …

ARDSmedicine.medical_specialtyBlood transfusionEmergency and Critical Caremedicine.medical_treatmentSurgery and Surgical Specialtieslcsh:MedicineInflammation030204 cardiovascular system & hematologyGeneral Biochemistry Genetics and Molecular BiologyPulmonary function testing03 medical and health sciences0302 clinical medicinemedicineExperimental modelAdverse effectRespiratory MedicineCrosstalkLungAnesthesiology and Pain ManagementWhole bloodInflammationLungbusiness.industryTransfusionGeneral Neurosciencelcsh:RBrain030208 emergency & critical care medicineHematologyGeneral Medicinemedicine.diseaseBloodPig modellmedicine.anatomical_structureAnesthesiaARDSHistopathologymedicine.symptomGeneral Agricultural and Biological SciencesbusinessPeerJ
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COVID-19 and periodontitis: reflecting on a possible association

2021

AbstractRecent studies have demonstrated a relationship between the severe clinical course of COVID-19 and other chronic diseases such as: cardiovascular disease, hypertension, diabetes mellitus, obesity and chronic renal disease. It may be possible to extend this association to a common and chronic oral disease in adults: periodontitis. Alternatively, the latter could be simply related to the systemic chronic diseases cited above, as already observed in the non-COVID-19 literature. In order to provide an overview and their opinion, the authors in this perspective article will report and discuss the most recent references of interest relating to COVID-19 and periodontitis pathophysiology. W…

Adult0301 basic medicineSpecialties of internal medicineDiseaseBioinformatics03 medical and health sciences0302 clinical medicineDiabetes mellitusmedicineHumansObesityPeriodontitisInterleukin 6General DentistryPeriodontitisIL-6biologySARS-CoV-2business.industryCOVID-19030206 dentistryHypothesismedicine.diseaseChronic periodontitisObesityPathophysiologyCoronavirusIL-17030104 developmental biologyRC581-951OtorhinolaryngologyChronic Diseasebiology.proteinNeurology (clinical)Interleukin 17businessHead & Face Medicine
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DR(high+)CD45RA(-)-Tregs potentially affect the suppressive activity of the total Treg pool in renal transplant patients.

2011

Recent studies show that regulatory T cells (Tregs) play an essential role in tolerance induction after organ transplantation. In order to examine whether there are differences in the composition of the total CD4(+)CD127(low+/-)FoxP3(+)- Treg cell pool between stable transplant patients and patients with biopsy proven rejection (BPR), we compared the percentages and the functional activity of the different Treg cell subsets (DR(high+)CD45RA(-)-Tregs, DR(low+)CD45RA(-)-Tregs, DR(-)CD45RA(-)-Tregs, DR(-)CD45RA(+)-Tregs). All parameters were determined during the three different periods of time after transplantation (0-30 days, 31-1,000 days, >1,000 days). Among 156 transplant patients, 37 pat…

AdultGraft Rejectionmedicine.medical_specialtymedicine.drug_classClinical Research DesignImmune Cellslcsh:Medicinechemical and pharmacologic phenomenaMonoclonal antibodyT-Lymphocytes RegulatoryOrgan transplantationInterleukin-7 Receptor alpha SubunitYoung AdultT-Lymphocyte SubsetsBiopsymedicineHumanslcsh:ScienceKidney transplantationAgedKidneyMultidisciplinarymedicine.diagnostic_testbusiness.industrylcsh:RInterleukin-2 Receptor alpha Subunithemic and immune systemsForkhead Transcription FactorsHLA-DR AntigensMiddle AgedImmunologic Subspecialtiesmedicine.diseaseKidney TransplantationTransplant rejectionTransplantationTolerance inductionmedicine.anatomical_structureNephrologyImmunologyLeukocyte Common AntigensMedicinelcsh:QClinical ImmunologySurgerybusinessResearch ArticlePloS one
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Long-term follow-up of hepatitis C virus-positive patients with persistently normal serum transaminases

2013

Material and methods. This study prospectively evaluated the progression of liver disease in a group of anti-HCV-positive patients with persistently normal ALT levels (PNALT) who were HCV-RNA positive. Patients selected for this study were those who presented with PNALT according to the Italian Association for the Study of the Liver (AISF) criteria in the year 1995/96 and underwent liver biopsy. They were divided into two groups according to their ALT evolution. Forty-five patients were included in this study. Results. After a median follow-up time of 180 months twenty-five of them maintained PNALT, but two of these developed liver cirrhosis (LC) in a mean time of 174 and 202 months, respec…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisLong term follow upSpecialties of internal medicineNormal serumChronic hepatitis CGastroenterologyAntiviral AgentsBody Mass IndexLiver diseaseInterferon treatmentInternal medicinemedicineHumansLongitudinal StudiesProspective StudiesUltrasonography Doppler ColorChronic hepatitis C. Persistently normal transaminases. Liver histology. Progression of disease. Interferon treatment.Proportional Hazards ModelsHepatologymedicine.diagnostic_testbusiness.industrySignificant differenceHistologyAlanine TransaminaseGeneral MedicineHepatitis C AntibodiesHepatitis C ChronicMiddle Agedmedicine.diseaseSurgeryHepatitis C Virus PositiveLiverRC581-951Liver biopsyDisease ProgressionElasticity Imaging TechniquesRNA ViralFemaleBiopsy Large-Core NeedlePersistently normal transaminasesbusinessLiver histologyProgression of disease
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Bovine pericardium based non-cross linked collagen matrix for successful root coverage, a clinical study in human

2012

Abstract Introduction The aim of this study was to clinically assess the capacity of a novel bovine pericardium based, non-cross linked collagen matrix in root coverage. Methods 62 gingival recessions of Miller class I or II were treated. The matrix was adapted underneath a coronal repositioned split thickness flap. Clinical values were assessed at baseline and after six months. Results The mean recession in each patient was 2.2 mm at baseline. 6 Months after surgery 86.7% of the exposed root surfaces were covered. On average 0,3 mm of recession remained. The clinical attachment level changed from 3.5 ± 1.3 mm to 1,8 ( ± 0,7) mm during the observational time period. No statistically signifi…

AdultMalePathologymedicine.medical_specialtylcsh:Specialties of internal medicineBovine pericardiumClinical NeurologyConnective tissueMatrix (biology)Gingival recessionClinical studylcsh:RC581-951medicineAnimalsHumansroot coverageddc:610Tooth RootGeneral Dentistryconnective tissueTissue Scaffoldsbusiness.industryDentistry(all)Researchguided tissue regenerationAnatomycollagen matrixMiddle Agedbovine pericardiumRoot coveragemedicine.anatomical_structureOtorhinolaryngologycardiovascular systemHead and neck surgeryGuided Tissue Regeneration PeriodontalCattleFemaleNeurology (clinical)CollagenbusinessPericardiumHead & Face Medicine
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Obesity and craniofacial variables in subjects with obstructive sleep apnea syndrome: comparisons of cephalometric values

2007

AbstractBackgroundThe aim of this paper was to determine the most common craniofacial changes in patients suffering Obstructive Sleep Apnea Syndrome (OSAS) with regards to the degree of obesity. Accordingly, cephalometric data reported in the literature was searched and analyzed.MethodsAfter a careful analysis of the literature from 1990 to 2006, 5 papers with similar procedural criteria were selected. Inclusion criteria were: recruitment of Caucasian patients with an apnea-hypopnea index (AHI) >10 as grouped in non-obese (Body Mass Index – [BMI] < 30)vs. obese (BMI ≥ 30).ResultsA low position of the hyoid bone was present in both groups. In non-obese patients, an increased value of t…

AdultMalePediatricsmedicine.medical_specialtylcsh:Specialties of internal medicineCephalometryPolysomnographyClinical NeurologyDentistryReviewPolysomnographySensitivity and SpecificitySeverity of Illness IndexBody Mass IndexTonguelcsh:RC581-951Reference ValuesRisk FactorsSeverity of illnessmedicineHumansObesityCraniofacialGeneral DentistryAgedSleep Apnea Obstructivemedicine.diagnostic_testDentistry(all)business.industryIncidenceSleep apneaMiddle AgedCraniometrymedicine.diseaseObesityrespiratory tract diseasesObstructive sleep apneaJawOtorhinolaryngologyCase-Control StudiesPharynxFemaleNeurology (clinical)Palate SoftbusinessBody mass indexHead & Face Medicine
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Condylar growth after non-surgical advancement in adult subject: a case report.

2007

Abstract Background A defect of condylar morphology can be caused by several sources. Case report A case of altered condylar morphology in adult male with temporomandibular disorders was reported in 30-year-old male patient. Erosion and flattening of the left mandibular condyle were observed by panoramic x-ray. The patient was treated with splint therapy that determined mandibular advancement. Eight months after the therapy, reduction in joint pain and a greater opening of the mouth was observed, although crepitation sounds during mastication were still noticeable. Conclusion During the following months of gnatologic treatment, new bone growth in the left condyle was observed by radiograph,…

AdultMalelcsh:Specialties of internal medicinemedicine.medical_treatmentClinical NeurologyDentistryCase ReportCondylestomatognathic systemlcsh:RC581-951Radiography PanoramicMedicineHumansGeneral DentistryMasticationReduction (orthopedic surgery)OrthodonticsBone growthbusiness.industryDentistry(all)Mandibular CondyleTemporomandibular Joint Disordersstomatognathic diseasesSplintsOtorhinolaryngologySplintsJoint painOral and maxillofacial surgeryNeurology (clinical)medicine.symptombusinessSplint (medicine)Headface medicine
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An examination of the psychometric structure of the Multidimensional Pain Inventory in temporomandibular disorder patients: a confirmatory factor ana…

2006

Abstract Background This paper seeks to analyse the psychometric and structural properties of the Multidimensional Pain Inventory (MPI) in a sample of temporomandibular disorder patients. Methods The internal consistency of the scales was obtained. Confirmatory Factor Analysis was carried out to test the MPI structure section by section in a sample of 114 temporomandibular disorder patients. Results Nearly all scales obtained good reliability indexes. The original structure could not be totally confirmed. However, with a few adjustments we obtained a satisfactory structural model of the MPI which was slightly different from the original: certain items and the Self control scale were elimina…

AdultMalemedicine.medical_specialtylcsh:Specialties of internal medicinePsychometricsAdolescentPsychometricsClinical NeurologyPainlcsh:RC581-951MedicineHumansTranslationsGeneral DentistryAgedPain MeasurementDentistry(all)business.industryResearchTemporomandibular disorderReproducibility of ResultsMiddle AgedTemporomandibular Joint DisordersConfirmatory factor analysisOtorhinolaryngologySpainHead and neck surgeryPhysical therapyPain psychologyMultidimensional pain inventoryFemaleNeurology (clinical)businessFactor Analysis StatisticalHead & Face Medicine
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A bibliometric analysis of scientific production in the field of lingual orthodontics

2019

Abstract Background Due to the lack of bibliometric studies in the field of lingual orthodontics in dentistry, the aim of this study was to assess the evolution and current status of activity in this field during the period 1978–2017. Methods A bibliometric analysis of the scientific articles indexed in the Science Citation Index-Expanded of the Web of Science and in the Scopus® database was performed using the truncated terms “ling* apppli*” or “ling* orthod*” or “ling* bracket*”. The types of texts included for analysis were limited to “articles” and “reviews”. The following information was extracted from each article identified: title, authors’ name(s), institutional affiliation(s), coun…

Bibliometric analysislcsh:Specialties of internal medicineLibrary scienceOrthodonticsLingual orthodonticsSubspecialtyBibliometric03 medical and health sciences0302 clinical medicineTonguelcsh:RC581-951HumansMedicineDental Care030223 otorhinolaryngologyGeneral Dentistrybusiness.industryBracketResearchScientific productionCorrection030206 dentistryCountry of originField (geography)Systematic reviewOtorhinolaryngologyBibliometricsLingualbibliometríaestomatologíaNeurology (clinical)businessCitationHead & Face Medicine
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Th17 immunity in children with allergic asthma and rhinitis: a pharmacological approach

2013

Th17 cells and IL-17A play a role in the development and progression of allergic diseases. We analyzed the IL-17A levels in sputum supernatants (Ss), nasal wash (NW) and plasma (P) from Healthy Controls (HC) and children with Asthma/Rhinitis. We tested the expression of IL-17A, RORγ(t) and FOXP3 in peripheral blood T-lymphocytes from intermittent and mild-moderate asthma. The effect of Budesonide and Formoterol was tested "in vitro" on IL-17A, RORγ(t) and FOXP3 expression in cultured T-lymphocytes from mild-moderate asthma/persistent rhinitis patients, and on nasal and bronchial epithelial cells stimulated with NW and Ss from mild-moderate asthma/persistent rhinitis. Further, the effect of …

BudesonideMalePulmonologyIL 13 and AsthmaGene ExpressionAnti-asthmatic AgentBiochemistryPediatricsimmune system diseasesFormoterol FumarateMolecular Cell BiologyAnti-Asthmatic AgentsBudesonideChildCells CulturedMultidisciplinaryImmune System ProteinsQInterleukin-17RFOXP3Forkhead Transcription FactorsNuclear Receptor Subfamily 1 Group F Member 3EthanolaminesMedicineFemaleInterleukin 17medicine.symptommedicine.drugResearch ArticleRhinitis Allergic PerennialAdolescentScienceImmunologyPediatric PulmonologyInflammationAdministration InhalationmedicineHumansAdrenergic beta-2 Receptor AgonistsBiologyAsthmaInflammationbusiness.industryInterleukin-8SputumImmunityProteinsImmunologic Subspecialtiesmedicine.diseaseNasal Lavage FluidAsthmarespiratory tract diseasesCase-Control StudiesImmunologySputumTh17 CellsClinical ImmunologyFormoterolbusinessPulmonary Immunology
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