Search results for "Spect"

Bcl-xL as a Modulator of Senescence and Aging

2021

Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…

Reflectance Measurement Method Based on Sensor Fusion of Frame-Based Hyperspectral Imager and Time-of-Flight Depth Camera

2022

Hyperspectral imaging and distance data have previously been used in aerial, forestry, agricultural, and medical imaging applications. Extracting meaningful information from a combination of different imaging modalities is difficult, as the image sensor fusion requires knowing the optical properties of the sensors, selecting the right optics and finding the sensors’ mutual reference frame through calibration. In this research we demonstrate a method for fusing data from Fabry–Perot interferometer hyperspectral camera and a Kinect V2 time-of-flight depth sensing camera. We created an experimental application to demonstrate utilizing the depth augmented hyperspectral data to measu…

Looking ahead in games research

2021

This thematic issue presents a number of emerging scholarships into the study of digital gaming. The articles are based on a 2019 symposium on game studies hosted by the Digital Games Research section of ECREA. As the phenomena related to digital gaming keep on evolving and emerging, so must research keep up with the times and constantly challenge itself. Whether speaking about validating previously developed research methods, imagining totally new ones, or even challenging the whole philosophy of science on which research is being done, there is a constant need for reappraisal and introspection within games research. As a cultural medium that has become deeply embedded into the social fabr…

Diseño, validación e implementación de un programa formativo basado en competencias curriculares dirigido a profesionales interdisciplinares que inte…

2021

Los hallazgos actuales a nivel mundial sobre la prevalencia del Trastorno del Espectro Autista (TEA) muestran un aumento del número de diagnósticos en la última década, como resultado de las mejoras en el desarrollo de instrumentos en la detección temprana y evolución en el consenso de los criterios diagnósticos. Sin embargo, la literatura ha evidenciado una gran falta tanto de conocimiento como de preparación en los profesionales que trabajan con personas TEA y con sus familias. El objetivo general del presente trabajo ha sido doble, ya que, por una parte, se han estudiado y abordado las necesidades formativas de profesionales multidisciplinares que intervienen a lo largo del ciclo vital d…

Real-world experience with dupilumab in severe asthma: One-year data from an italian named patient program

2021

Raffaele Campisi,1 Claudia Crimi,1 Santi Nolasco,2 Bianca Beghè,3 Leonardo Antonicelli,4 Gabriella Guarnieri,5 Nicola Scichilone,6 Morena Porto,2 Luigi Macchia,7 Giulia Scioscia,8 Maria Pia Foschino Barbaro,8 Alberto Papi,9 Nunzio Crimi1,2 1Respiratory Medicine Unit, A.O.U. Policlinico “G. Rodolico -San Marco”, Catania, Italy; 2Department of Clinical and Experimental Medicine, Section of Respiratory Diseases, University of Catania, Catania, Italy; 3Respiratory Medicine Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4Allergy Unit, Department of Internal Medicine, Ancona University Hospital, Ancona, Italy; 5Department of Car…

Omalizumab outcomes for up to 6 years in pediatric patients with severe persistent allergic asthma

2021

BACKGROUND: Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe the long-term outcomes of pediatric patients with severe persistent allergic asthma receiving omalizumab in the largest real-life cohort reported to date. METHODS: ANCHORS was a multicenter, observational, retrospective cohort study conducted in 25 Pediatric Allergy and Pulmonology units in Spain. We collected data of patients < 18 years and initiating omalizumab between 2006 and 2018, from the year prior to omalizumab initiation to discontinuation or last available follow-up. The primary outcome was the evolution of…

The hidden burden of severe asthma: from patient perspective to new opportunities for clinicians

2020

Severe asthma is an important topic in respiratory diseases, due to its high impact on morbidity and mortality as well as on health-care resources. The many challenges that still exist in the management of the most difficult-to-treat forms of the disease, and the acknowledgement of the existence of unexplored areas in the pathophysiological mechanisms and the therapeutic targets represent an opportunity to gather experts in the field with the immediate goals to summarize current understanding about the natural history of severe asthma and to identify gaps in knowledge and research opportunities, with the aim to contribute to improved medical care and health outcomes. This article is a conse…

Iperviscosita' sclerocitemica da alterazioni congenite della membrana eritrocitaria

2009

‘‘This is my home, too’’: Migration, spectrality and hospitality inRoberta Torre’s Sud Side Stori (2000)

2011

The article explores Roberta Torre’s film Sud Side Stori (2000), an extravagant Italian re-vision of Romeo and Juliet set in the Sicilian city of Palermo which displays awareness of the global circulation of the story of the two ‘‘star-crossed lovers’’. In the film, which combines neo-realist cinematographic techniques with the artificial style of the musical, Shakespeare’s young lovers become Toni Giulietto, a lousy local rock singer, and Romea Wacoubo, a beautiful Nigerian prostitute who falls in love with him when she sees him standing on his balcony. Not unlike West Side Story, the inter-racial passion between Toni and Romea exacerbates pre-existing ethnic conflicts. It is opposed not o…

Spectrum-shape method and the next-to-leading-order terms of the β-decay shape factor

2017

Effective values of the axial-vector coupling constant gA have lately attracted much attention due to the prominent role of gA in determining the half-lives of double β decays, in particular their neutrinoless mode. The half-life method, i.e., comparing the calculated half-lives to the corresponding experimental ones, is the most widely used method to access the effective values of gA. The present paper investigates the possibilities offered by a complementary method: the spectrum-shape method (SSM). In the SSM, comparison of the shapes of the calculated and measured β electron spectra of forbidden nonunique β decays yields information on the magnitude of gA. In parallel, we investigate the…