Search results for "Sport System"
showing 10 items of 82 documents
SNAT2 silencing prevents the osmotic induction of transport system A and hinders cell recovery from hypertonic stress.
2005
AbstractUnder hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. In hypertonically stressed human fibroblasts transfection with two siRNAs for SNAT2 suppressed the increase in SNAT2 mRNA and the stimulation of system A transport activity. Under the same condition, the expansion of the intracellular amino acid pool was significantly lowered and cell volume recovery markedly delayed. It is concluded that the up-regulation of SNAT2 is essential for the rapid restoration of cell volume after hypertonic stress.
Between the Megalopolis and the Deep Blue Sky: Challenges of Transport with UAVs in Future Smart Cities
2019
International audience; With the rapid increase of the world's urban population, the infrastructure of the constantly expanding metropolitan areas is undergoing an immense pressure. To meet the growing demands of sustainable urban environments and improve the quality of life for citizens, municipalities will increasingly rely on novel transport solutions. In particular, Unmanned Aerial Vehicles (UAVs) are expected to have a crucial role in the future smart cities thanks to their interesting features such as autonomy, flexibility, mobility, adaptive altitude, and small dimensions. However, densely populated megalopolises of the future are administrated by several municipals, governmental and…
Il procuratore sportivo negli U.S.A.: spunti di riflessione per il sistema sportivo nazionale.
2012
Management of intelligent transport systems applied to sustainable development of motor vehicle transports
2021
The scientific paper presents a concrete research carried out by the authors in order to implement technical concepts, so that those interested in this field can learn about a certain way of exposing the problems with regard to the sustainable development of road transport. The use of computer means in the field of motor vehicle transport have taken on a special magnitude in recent times, and the Intelligent Transport Systems (ITS), also known as telematics systems used in the field of transport, comprise a wide range of tools and services deriving from ITS technologies, by using communications and information technology. Below we present a technical and managerial study with engineering nu…
Aspects regarding the research in the field of electric vehicles implementation in the context of the sustainable development of the European road tr…
2021
The scientific paper presents a concrete research carried out by the authors in order to implement some concepts of a technical nature, so that those interested in this field can get acquainted about a certain way of exposing the problems regarding the actions taken by the European authorities, regarding the implementation of electric vehicles at the level of some EU states, in the context of the sustainable and durable development of the European road transport system. Below we present a technical and managerial study with engineering nuances, through which readers can look at and understand the concept of sustainable development of this sector in a global context, through which we will de…
Innovative transport services in areas with weak and peculiar public transport demand
2008
A growing demand for mobility and the deficiencies in the transport system have transformed urban centres in “unliveable” places. A prevalent use of private cars produces high levels of pollution, casualties and road congestion. The promotion of public transport is considered an effective strategy to make mobility more sustainable for people. When a public transport system serves areas with a weak transportation demand, as it happens in territories with dispersed settlements (urban outskirts, rural areas, mountains, …), the resort to unconventional forms of public transport, such as dial and ride bus services, is necessary.
Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity.
2002
Member 4 of human solute carrier family 7 (SLC7A4) exhibits significant sequence homology with the SLC7 subfamily of human cationic amino acid transporters (hCATs) [Sperandeo, Borsani, Incerti, Zollo, Rossi, Zuffardi, Castaldo, Taglialatela, Andria and Sebastio (1998) Genomics 49, 230–236]. It is therefore often referred to as hCAT-4 even though no convincing transport activity has been shown for this protein. We expressed SLC7A4 in Xenopus laevis oocytes, but could not detect any transport activity for cationic, neutral or anionic amino acids or for the polyamine putrescine. In addition, human glioblastoma cells stably overexpressing a fusion protein between SLC7A4 and the enhanced green f…
A Feasibility Analysis For Wig’s As A Civil Transport System In The Mediterranean Sea
2008
Expression, regulation and function of carrier proteins for cationic amino acids.
2001
Different carrier proteins exhibiting distinct transport properties participate in cationic amino acid transport. There are sodium-independent systems, such as b+, y+, y+L and b0,+, and a sodium-dependent system B0,+, most of which have now been identified at the molecular level. In most non-epithelial cells, members of the cationic amino acid transporter (CAT) family mediating system y+ activity seem to be the major entry pathway for cationic amino acids. CAT proteins underlie complex regulation at the transcriptional, post-transcriptional and activity levels. Recent evidence indicates that individual CAT isoforms are necessary for providing the substrate for nitric oxide synthesis, for ex…
Plasma membrane transporters for arginine
2004
The supply of arginine may become rate limiting for enzymatic reactions that use this semiessential amino acid as a substrate (e.g., nitric oxide, agmatine, creatine, and urea synthesis), particularly under conditions of high demand such as growth, sepsis, or wound healing. In addition, arginine acts as a signaling molecule that regulates essential cellular functions such as protein synthesis, apoptosis, and growth. In the past decade, a number of carrier proteins for amino acids have been identified on the molecular level. They belong to different gene families, exhibit overlapping but distinctive substrate specificities, and can further be distinguished by their requirement for the cotran…