Search results for "Spot"
showing 10 items of 371 documents
Dark coupling
2009
30 pages, 10 figures, 3 tables.-- Pre-print archive.
SOUTHTRAC-GW: An airborne field campaign to explore gravity wave dynamics at the world’s strongest hotspot
2021
The southern part of South America and the Antarctic peninsula are known as the world’s strongest hotspot region of stratospheric gravity wave (GW) activity. Large tropospheric winds are deflected by the Andes and the Antarctic Peninsula and excite GWs that might propagate into the upper mesosphere. Satellite observations show large stratospheric GW activity above the mountains, the Drake Passage, and in a belt centered along 60°S. This scientifically highly interesting region for studying GW dynamics was the focus of the Southern Hemisphere Transport, Dynamics, and Chemistry–Gravity Waves (SOUTHTRAC-GW) mission. The German High Altitude and Long Range Research Aircraft (HALO) was deployed …
Novel M. tuberculosis specific IL-2 ELISpot assay discriminates adult patients with active or latent tuberculosis
2018
Background Tuberculosis (TB) still is a major worldwide health problem, with 10.4 million new cases in 2016. Only 5–15% of people infected with M. tuberculosis develop TB disease while others remain latently infected (LTBI) during their lifetime. Thus, the absence of tests able to distinguish between latent infection and active tuberculosis is one of the major limits of currently available diagnostic tools. Methods A total of 215 patients were included in the study as active TB cases (n = 73), LTBI subjects (n = 88) and healthy persons (n = 54). Peripheral blood mononuclear cells (PBMCs) were isolated from each patient and the LIOSpot® TB anti-human IL-2 ELISpot assay was performed to test …
Dynamic Antigen Presentation Patterns of Listeria monocytogenes-Derived CD8 T Cell Epitopes In Vivo
2001
Abstract Little information exists regarding the presentation of antigenic peptides in infected tissues. In this study the in vivo presentation of four different CD8 T cell epitopes of Listeria monocytogenes was monitored. Peptide presentation was measured by a new, highly sensitive, ex vivo Ag presentation assay that was based on the testing of freshly isolated cells from infected spleens with peptide-specific CD8 T cell lines in an IFN-γ-specific ELISPOT assay. Remarkably, the peptide presentation pattern of splenocytes and that of macrophages purified from spleens of L. monocytogenes-infected mice were different from those of in vitro infected macrophage-like cell lines. The in vivo Ag p…
In vitro evaluation of bacteriocinlike inhibitory substances produced by lactic acid bacteria isolated during traditional sicilian cheese making
2016
Bacteriocins are antimicrobial proteins produced by bacteria that inhibit with a bactericidal or bacteriostatic mode of action, the growth of other bacteria. Many lactic acid bacteria (LAB) produce a high diversity of different bacteriocins. Bacteriocinogenic LAB are generally recognized as safe (GRAS) and useful to control the frequent development of pathogens and spoilage microorganisms; for this reason they are commonly used as starter cultures in food fermentations. In this study, the authors describe the results of a screening on 699 LAB isolated from wooden vat surfaces, raw milk and traditional Sicilian cheeses, for the production of bacteriocin-like inhibitory substances (BLIS), by …
Accretion of arc-oceanic lithospheric mantle in the Mediterranean: Evidence from extremely high-Mg olivines and Cr-rich spinel inclusions in lamproit…
2007
Abstract Si-rich Mediterranean type lamproites (48–56 wt.% SiO2) are olivine-phyric, mantle-derived volcanics, in which both phenocrystic and xenocrystic olivine are present. Here we demonstrate the phenocrystic origin of the most extremely NiO–MgO enriched olivine in lamproites with Mg# up to 0.95, that host Cr-rich (Cr# around 0.95) spinels. Our comprehensive study of olivine–spinel pairs from Mediterranean lamproites enables us to constrain the extent of depletion of their mantle source. Olivine–spinel pairs from primitive Mediterranean lamproites plot in the most refractory part of the olivine–spinel mantle array diagram, showing even more refractory character than mineral pairs from bo…
Composition and provenance analysis of beach sands in an almost isolated sedimentary system – A field study of the Galápagos Archipelago
2021
The Galapagos Archipelago is the surface expression of an active hotspot or long-lived mantle plume. The Archipelago consists of a group of 13 main islands which are located in the eastern central Pacific Ocean about 1,000 km west of the northern edge of the South American continent, east of the East Pacific Rise and south of the Galapagos spreading center. Because of the large distance to the nearest continental land mass, Galapagos can be seen as an almost isolated sedimentary system. A provenance study conducted on samples collected from seventeen beaches on eleven islands, demonstrates that mineral grains and particles were derived from weathering of predominantly basaltic rocks and wer…
A comparative quantitative & qualitative assessment in orthodontic treatment of white spot lesion treated with 3 different commercially available mat…
2019
Background To comparatively evaluate the esthetic improvement of white-spot lesions (WSLs) treated by: BiominF, CPP-ACP paste with fluoride & ICON resin infiltration, using Spectrophotometer & Diagnodent. Material and Methods The study was done using 72 sound permanent extracted premolars, divided into four groups (18 teeth per group). After taking the ethical approval the study was commenced. WSLs were created on human premolars and randomly assigned to four groups: Group A: Artificial Saliva, Group B: CPP-ACP with fluoride, Group C: BiominF, Group D: Resin infiltration (Icon). The color change (∆E) of each specimen was measured with a Spectrophotometer (VITA Easy Shade Compact), and fluor…
Basil (Ocimum basilicum), a new host of Pepino mosaic virus.
2009
Pepino mosaic virus (PepMV), a member of the genus Potexvirus , was first described in 1980 on pepino ( Solanum muricatum ) and was later isolated from different wild species of the genus Solanum (formerly Lycopersicon ) (Soler et al ., 2002). PepMV has been reported in several European countries and in North America, causing disease in tomato. In July 2008, plants of basil ( Ocimum basilicum ) showing interveinal chlorosis on young leaves were observed in three greenhouses in Sicily, in the area where tomato plants were found to be infected by PepMV in 2005 (Davino et al ., 2006). The disease was transmitted mechanically to Nicotiana benthamiana , producing chlorotic spots and leaf deforma…
Mammal assemblage composition predicts global patterns in emerging infectious disease risk
2021
Abstract As a source of emerging infectious diseases, wildlife assemblages (and related spatial patterns) must be quantitatively assessed to help identify high‐risk locations. Previous assessments have largely focussed on the distributions of individual species; however, transmission dynamics are expected to depend on assemblage composition. Moreover, disease–diversity relationships have mainly been studied in the context of species loss, but assemblage composition and disease risk (e.g. infection prevalence in wildlife assemblages) can change without extinction. Based on the predicted distributions and abundances of 4466 mammal species, we estimated global patterns of disease risk through …