Search results for "Stability."
showing 10 items of 3015 documents
Degradation of heterocyclic aromatic amines in oil under storage and frying conditions and reduction of their mutagenic potential.
2007
Heterocyclic aromatic amines (HAA) were systematically studied concerning their partition behavior in water/oil-systems and their thermostability in different animal derived fats and vegetable oils. Partitioning of IQx-compounds and PhIP in water/oil systems was found to depend on the polarity defined by the molecular structure and on the pH-value of the aqueous phase. In particular, beta-carbolines norharman and harman showed a significant strong lipophilic character at alkaline pH. After heating in frying fats at 130 degrees C, contents of IQx compounds and PhIP were reduced by more than 40% and after heating at 180 degrees C less than 10% of the HAA initial concentration was recovered. B…
Curcumin as Scaffold for Drug Discovery against Neurodegenerative Diseases
2021
Neurodegenerative diseases (NDs) are one of major public health problems and their impact is continuously growing. Curcumin has been proposed for the treatment of several of these pathologies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) due to the ability of this molecule to reduce inflammation and aggregation of involved proteins. Nevertheless, the poor metabolic stability and bioavailability of curcumin reduce the possibilities of its practical use. For these reasons, many curcumin derivatives were synthetized in order to overcome some limitations. In this review will be highlighted recent results on modification of curcumin scaffold in the search of new effective therap…
Structural invariance and stability of sense of coherence: A longitudinal analysis of two groups with different employment experiences
2005
This 5-year follow-up study investigated the structure and the factorial invariance of the 13-item sense of coherence (SOC) scale (Antonovsky, 1987a) in two employment groups (unemployment/lay-off experiences vs. continuous full-time employment) and across two measurement times. In addition, the stability of SOC between these two employment groups was compared. The postal questionnaire data was collected twice, in 1992 and in 1997. The participants were Finnish technical designers (N=352) aged between 25 and 40 years in 1992. A total of 51% of the investigated participants had been employed full-time during the 5-year follow-up period and 49% had been unemployed and/or laid off for a total …
Deriving scaling laws in geodynamics using adjoint gradients
2018
Abstract Whereas significant progress has been made in modelling of lithospheric and crustal scale processes in recent years, it often remains a challenge to understand which of the many model parameters is of key importance for a particular simulation. Determining this is usually done by manually changing the model input parameters and performing new simulations. For a few cases, such as for folding or Rayleigh-Taylor instabilities, one can use thick-plate stability analysis to derive scaling laws to obtain such insights. Yet, for more general cases, it is not straightforward to do this (apart from running many simulations). Here, we discuss a numerically cheaper approach to compute scalin…
Numerical study of the components positioning influence on the stability of a reverse shoulder prosthesis
2014
Aim of this paper is to setup a novel procedure able to analyze performances of a reverse shoulder prosthesis when different geometrical configurations are assumed. Nowadays, such a prosthesis is widely used but, because of its novelty, data in literature give poor information about performances and limits to its applicability. The activity has been divided into the following steps. At the beginning the shape of the prosthesis has been digitally acquired via a 3D scanner. Then, CAD models of all prosthetic components have been geometrically optimized in a way to obtain final entities suitable for numerical simulations. After that, CAD assemblies have been created between prosthetic componen…
Competition between heterogeneous and homogeneous nucleation near a flat wall
2009
We studied the competition between heterogeneous and homogeneous nucleation of an aqueous suspension of charged colloidal spheres close to the container walls. Samples of equilibrium crystalline structure were shear-melted and the metastable melt left to solidify after the cessation of shear. The crystallization kinetics was monitored using time-resolved scattering techniques: at low particle number densities n we applied an improved static light scattering method while at large particle concentrations ultra-small-angle x-ray scattering was applied for the first time. Our results show some unexpected behavior: the heterogeneous nucleation at the container walls is delayed in comparison to t…
Adaptive control of a class of strict-feedback time-varying nonlinear systems with unknown control coefficients
2018
Abstract In this paper, robust adaptive control of a class of strict-feedback nonlinear systems with unknown control directions is investigated. A novel Nussbaum-type function is developed and a key theorem is drawn which involves quantifying the addition of multiple Nussbaum functions with different control directions in a single inequality. Global stability of the closed-loop system and asymptotic stabilization of system output are proved. A simulation example is given to illustrate the effectiveness of the proposed control scheme.
The PCHIP subdivision scheme
2016
In this paper we propose and analyze a nonlinear subdivision scheme based on the monotononicity-preserving third order Hermite-type interpolatory technique implemented in the PCHIP package in Matlab. We prove the convergence and the stability of the PCHIP nonlinear subdivision process by employing a novel technique based on the study of the generalized Jacobian of the first difference scheme. MTM2011-22741
Controlling and learning motor functions
2018
Effective and adaptive motor functions are important for living beings and developing computational and learning mechanisms for roving robots is a crucial aspect in biorobotics. In this chapter we report a new architecture for motor learning to be applied in insect-like walking robots. The proposed model is based on the MB structure previously introduced able to memorize time evolutions of key parameters of the neural motor controller to improve existing motor primitives. The adopted control scheme enables the structure to efficiently cope with goal-oriented behavioural motor tasks. The problem of body-size evaluation is also considered and a model for the parallax-based estimation is provi…
Generalized wavelets design using Kernel methods. Application to signal processing
2013
Abstract Multiresolution representations of data are powerful tools in signal processing. In Harten’s framework, multiresolution transforms are defined by predicting finer resolution levels of information from coarser ones using an operator, called the prediction operator, and defining details (or wavelet coefficients) that are the difference between the exact values and the predicted values. In this paper we present a multiresolution scheme using local polynomial regression theory in order to design a more accurate prediction operator. The stability of the scheme is proved and the order of the method is calculated. Finally, some results are presented comparing our method with the classical…