Search results for "Stability."
showing 10 items of 3015 documents
Synthesis of mesoporous silica nanoparticles (MSNs) and encapsulation of cisplatin for targeted cancer therapies
2014
The aim of this PhD thesis is to elaborate mesoporous silica nanoparticles (MSNs) able to sustain the release of cisplatin into the intracellular compartments of solid tumors. The parametric study shows that morphological, structural and textural properties of MSNs-MCM-41, synthesized by sol-gel reaction by using TEOS as a silica source and CTAB as a structure-directing agent, depend on pH, stirring speed, temperature and extraction process of CTAB. The synthesis atmosphere has to be controlled in order to avoid the presence of ethanol and carbonate species which are responsible of necks between particles generating unstable suspensions of MSNs.MSNs were functionalized in order to control t…
Dryland vegetation pattern dynamics driven by inertial effects and secondary seed dispersal
2022
This manuscript tackles the study of vegetation pattern dynamics driven by inertial effects and secondary seed dispersal. To achieve this goal, an hyperbolic extension of the classical parabolic Klausmeier model of vegetation, generally used to predict the formation of banded vegetation along the slopes of semiarid environments, has been here considered together with an additional advective term mimicking the downslope motion of seeds. Linear stability analyses have been carried out to inspect the dependence of the wave instability locus on the model parameters, with particular emphasis on the role played by inertial time and seed advection speed. Moreover, periodic travelling wave solution…
Innovative Vehicle-Trailer Connection for Yaw Stability Improvement
2014
As well known, dangerous conditions may occur for the lateral stability of the road vehicles on increasing the running velocity. While it is easy to make up for this drawback in the case of a vehicle alone, by a proper weight distribution, the unstable trend may worsen unfavourably for the vehicle-trailer configuration, imposing a very hard correction task to the driver, who has to cope with the development of two types of instability, exponentially divergent or swaying with increasing amplitude. The critical velocity depends on the geometrical and inertial characteristics of the car-trailer system, on the cornering stiffness of the tires and on the weight distribution among the axles. The …
QSPR/QSAR Studies of 2-Furylethylenes Using Bond-Level Quadratic Indices and Comparison with Other Computational Approaches
2017
The recently introduced, non-stochastic and stochastic quadratic indices (Marrero-Ponce <em>et al. J. Comp. Aided Mol. Des.</em> 2006, 20, 685-701) were applied to QSAR/QSPR studies of heteroatomic molecules. These novel bond-based molecular descriptors (MDs) were used for the prediction of the partition coefficient (log P), and the antibacterial activity of 34 derivatives of 2-furylethylenes. Two statistically significant QSPR models using non-stochastic and stochastic bond-based quadratic indices were obtained (R<sup>2</sup> = 0.971, s = 0.137 and R<sup>2</sup> = 0.986, s = 0.096). These models showed good stability to data variation in leave-one-out (L…
Vibration control of vehicle engine-body systems with time delay: an LMI approach
2013
The objective of this chapter is to study the problem of vibration control analysis and synthesis in a vehicle engine-body vibration structure. It is assumed that the actuator is subject to a time-varying delay for control of bounce and pitch vibrations. Based on a Lyapunov-Krasovskii functional and using some free weighting matrices, delay-dependent sufficient conditions for designing desired state- and output-feedback controllers are given in terms of linear matrix inequalities (LMIs). The state- and output-feedback controllers, which guarantee asymptotic stability with a prescribed γ-level L2-gain (or H∞ performance), are then developed directly instead of coupling the second-order model…
A convex optimization approach for vibration control of base isolated structures with limited wireless communication capacity
2010
The problem of H ∞ control design for vibration reduction of a base isolated structure with limited wireless communication capacity is studied in this paper. The network under consideration is subjected to measurement quantization, signal transmission delay, and data packet dropout, which appear typically in a network environment. Based on Lyapunov-Krasovskii functional (LKF) theory, some delay-range-dependent conditions are established for the existence of desired controllers such that the resulting closed-loop system is asymptotically stable and its performance is kept within a prescribed level. Finally, some simulation results are given to illustrate the effectiveness of our method.
Feedback vibration control of a base-isolated building with delayed measurements using h<inf>&#x221E;</inf> techniques
2010
In this paper we address the problem of vibration reduction of buildings with delayed measurements, where the delays are time-varying and bounded. We focus on a convex optimization approach to the problem of state-feedback H ∞ control design. An appropriate Lyapunov-Krasovskii functional and some free weighting matrices are used to establish some delay-range-dependent sufficient conditions for the design of desired controllers in terms of linear matrix inequalities (LMIs). The controller, which guarantees asymptotic stability and an H ∞ performance, simultaneously, for the closed-loop system of the structure, is then developed. The performance of the controller is evaluated through the simu…
Comparative Study of Different Methods for the Prediction of Drug–Polymer Solubility
2015
In this study, a comparison of different methods to predict drug-polymer solubility was carried out on binary systems consisting of five model drugs (paracetamol, chloramphenicol, celecoxib, indomethacin, and felodipine) and polyvinylpyrrolidone/vinyl acetate copolymers (PVP/VA) of different monomer weight ratios. The drug-polymer solubility at 25 °C was predicted using the Flory-Huggins model, from data obtained at elevated temperature using thermal analysis methods based on the recrystallization of a supersaturated amorphous solid dispersion and two variations of the melting point depression method. These predictions were compared with the solubility in the low molecular weight liquid ana…
PHA Latex Composite Films: Mechanical Properties and Surface Visualization
2013
Homopolymer PHB and copolymer PHB/HV containing granules were isolated from Azotobacter chroococcum cells and used for latexes formation. Composite latex films were formed from the PHB and PHB/HV latexes with different content of poly (vinyl alcohol) and glycerol and a hydrophobic fluorescent benzanthrone derivated dye 3-piperidinobenzanthrone, possessed high fluorescence intensity in a system with PHA granules. Fluorescence based methods were used for characterization of the elaborated latex film by their stability at high temperature and for visualization of the film surfaces PHA granules distribution. Film stability in phosphate buffered saline was evaluated by dye migration activity in …
Enzymes involved in vinyl acetate decomposition by Pseudomonas fluorescens PCM 2123 strain
2014
Esterases are widely used in food processing industry, but there is little information concerning enzymes involved in decompositions of esters contributing to pollution of environment. Vinyl acetate (an ester of vinyl alcohol and acetic acid) is a representative of volatile organic compounds (VOCs) in decomposition, of which hydrolyses and oxidoreductases are mainly involved. Their activities under periodically changing conditions of environment are essential for the removal of dangerous VOCs. Esterase and alcohol/aldehyde dehydrogenase activities were determined in crude cell extract from Pseudomonas fluorescens PMC 2123 after vinyl acetate induction. All examined enzymes exhibit their hig…