Search results for "Stage"
showing 10 items of 1393 documents
The course of fatigue in patients with gynecologic and breast cancer
2013
Objective: The objective of this study is to examine the course of fatigue in female cancer patients during the first months after treatment. Methods: We examined a sample of 110 patients suffering from gynecological or breast cancer. Fatigue was assessed with two questionnaires, the Multidimensional Fatigue Inventory (MFI) and the fatigue scale of the quality of life questionnaire European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30). Participants were tested during their stay in the hospital (t1), two weeks after discharge (t2), and three months after discharge (t3). Results: Fatigue in the patients’ sample was markedly higher than the general population reference val…
Heavy quark momentum diffusion coefficient in 3D gluon plasma
2020
We study the heavy-quark momentum diffusion coefficient in far from equilibrium gluon plasma in a self-similar regime using real-time lattice techniques. We use 3 methods for the extraction: an unequal time electric field 2-point correlator integrated over the time difference, a spectral reconstruction (SR) method based on the measured equal time electric field correlator and a kinetic theory (KT) formula. The time-evolution of the momentum diffusion coefficient extracted using all methods is consistent with an approximate $t^{\frac{-1}{2}}$ power law. We also study the extracted diffusion coefficient as a function of the upper limit of the time integration and observe that including the in…
Curative therapies for hepatocellular carcinoma: an update and perspectives.
2015
Curative treatments, including liver transplantation, surgical resection and percutaneous treatments, are the recommended therapies in BCLC-0 (Barcelona Clinic of Liver Cancer) or BCLC-A hepatocellular carcinoma (HCC). This review provides an overview of some issues of clinical importance concerning curative treatments in HCC.
Vertical transmission of naturally occurring Bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of L…
2018
Background Many arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in East Africa. Although epidemics of arboviral emerging infectious diseases have risen in frequency in recent years, the extent to which mosquitoes maintain pathogens in circulation during inter-epidemic periods is still poorly understood. This study aimed to investigate whether arboviruses may be maintained by vertical transmission via immature life stages of different mosquito vector species. Methodology We collected immature mosquitoes (egg, larva, pupa) on the shores and islands of Lake Baringo and Lake Victoria in western Kenya and reared them to adults. Mo…
Tubular cell damage may be the earliest sign of renal extrahepatic manifestation caused by Hepatitis C
2021
Publisher Copyright: © 2021 Kaartinen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Chronic kidney disease (CKD) is one of the most well-known extrahepatic manifestations caused by hepatitis C infection (HCV). CKD is typically discovered at a late stage. HCVnephropathy may show different histopathologic patterns, as both glomerular and tubulointerstitial damage have been described. Identification of patients with early renal manifestations would be beneficial to provide treatment and avoid progres…
TL-dating applied to building archaeology: The case of the medieval church Notre-Dame-Sous-Terre (Mont-Saint-Michel, France)
2007
Abstract The recent application of thermoluminescence (TL) dating to young building materials is being increasingly developed for use in the field of buildings archaeology [ Bailif, I.K., Holland, N., 2000. Dating bricks of the two last millennia from Newcastle upon Tyne: a preliminary study. Radiat. Meas. 32, 615–619 ; Gallo N, Fieni L, Martini M, Sibillia E, 1999. Building archaeology, 14C and thermoluminescence: two examples comparison, Actes du Colloque, “C14 et Archeologie”, III e Congres International, Lyon 6–10 avril 1998, Memoire de Societe prehistorique Francaise, tome XXVI et Supplement de la revue d’Archeometrie, pp. 425–431 ; Vieillevigne, E., Guibert, P., Bechtel, F., Leriche, …
Rektummelanome – Stellenwert der modernen Therapie
2008
Rectal melanoma is a rare disease. There is much controversy concerning cause, incidence and treatment of the disease and the spreading of recurrence. In this article, we discuss actual aspects of diagnostic, therapy and prognosis on the basis of our series of seven patients as well as a literature review. The surgical therapy in the form of local tumour excision with a disease-free margin of up to 1-2 cm is the initial therapeutic modality of choice. Large tumours that obviously could not be removed in sano should be treated with a multimodal concept. Such tumours should be treated by a combination of neoadjuvant radiation and chemotherapy for down-staging with subsequent local excision (L…
Soft tissue sarcoma in Italy: From epidemiological data to clinical networking to improve patient care and outcomes
2019
Sarcomas are rare malignant neoplasms that develop from mesenchymal cells and include a heterogeneous and large group of histological subtypes that may occur at any anatomical site. Soft tissue sarcomas (STS), the focus of this review, account for ≈70‒80% of sarcomas and represent <1% of all cancers. The heterogeneity of STS applies to both their topography and morphology, and 5-year survival can vary widely depending on disease stage and the complex interplay between anatomical site and histology for different STS subtypes. The rarity and heterogeneity of STS, together with other factors, such as the lack of clinical expertise often lead to difficulties and delays in making an accurate …
Ethics and economics, friends or foes? An educational debate
2004
This paper reviews an ongoing debate about moral standards for vocational education in German speaking countries. At the centre of the controversy is the question of universalistic versus domain‐specific moral orientations, namely the question of whether business people ought to develop different moral points of view in different situations (such as ‘private’ versus ‘professional’). Of pivotal importance in this context is also a prominent ethical approach (by Karl Homann, a philosopher in the tradition of liberal economists) which serves as a foundation for those who advocate domain specificity and which is strongly criticized by their counterparts. This approach is also presented, since t…
Dépistage du cancer du sein : en route vers le futur
2016
Breast cancer remains a potentially lethal disease, which requires aggressive treatments and is associated with long-term consequences. Its prognosis is linked to both tumor biology and burden at diagnosis. Although treatments have allowed important improvements in prognosis over the past 20 years, breast cancer screening remains necessary. Mammographic screening allows earlier stage diagnoses and a decrease of breast cancer specific mortality. However, breast cancer screening modalities should be revised with the objective to address demonstrated limitations of mammographic screening (limited benefit, imperfect sensitivity and specificity, overdiagnoses, radiation-induced morbidity). Furth…