Search results for "Standard"

showing 10 items of 3299 documents

Law and morals in the application of the public policy exception under the twin regulations 1103 and 1104 of 2016

2021

This paper discusses the interactions between fundamental principles of domestic legal systems and non-legal standards in the application of the public policy Generalklausel within the context of the twin Regulations 1103 and 1104 of 2016. In particular, this paper argues that public policy is composed of legal principles only and that there is no space for extra legal standards when the circulation of foreign deeds, decisions and laws is in discussion. This consideration has two consequences. Firstly, the role of good morals within contemporary private international law is extremely reduc

:CIENCIAS JURÍDICAS [UNESCO]Soft Law. 324 349Soft Law.Derechodecisions and laws is in discussion. This consideration has two consequences. FirstlyAnulación de las reglas obligatoriasBuena fePublic PolicyGood MoralsGeneralklauselnMoralGiovanni This paper discusses the interactions between fundamental principles of domestic legal systems and non-legal standards in the application of the public policy Generalklausel within the context of the twin Regulations 1103 and 1104 of 2016. In particular2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113565 Law and morals in the application of the public policy exception under the twin regulations 1103 and 1104 of 2016 ZarraOverriding Mandatory RulesOrden públicoUNESCO::CIENCIAS JURÍDICASthis paper argues that public policy is composed of legal principles only and that there is no space for extra legal standards when the circulation of foreign deedsthe role of good morals within contemporary private international law is extremely reduc Morals
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The Divorce allowance in Italy, between Rules and Principles

2019

Italian law gives the right to a maintenance allowance to the spouse who does not have ?mezzi adeguati?. The assumption consisting in the ?mancanza di mezzi adeguati?, originally understood by the Joint Sections of the Italian Cassation of 1990 as a lack of resources to maintain the standard of living enjoyed during the marriage, was understood by the Court of Cassation in 2017 as a lack of resources of guaranteeing independence or economic self-sufficiency. In the essay, the author shares this new approach and clarifies that the new interpretation is consistent with the principles and values of the Italian legal system. The author therefore offers arguments to support this new interpretati…

:CIENCIAS JURÍDICAS [UNESCO]UNESCO::CIENCIAS JURÍDICASeconomic independencefamily solidaritymaintenance allowanceSpousesdivorceSpouses; divorce; maintenance allowance; family solidarity; standard of living; economic independencestandard of living
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La interpretación jurídica con perspectiva de género : Un decálogo de estándares interpretativos

2021

: The Argentine legal system is part of the constitutional paradigm. In this case, the gender perspective is an essential condition to make a legal correct interpretation because its postulates influence any notion and course of legal action. On this matter, I assume a theoretical foundation of the gender theory and I recommend a decalogue of interpretative standards which receive its vision.

:CIENCIAS JURÍDICAS [UNESCO]gender perspectiveinterpretación jurídicaI assume a theoretical foundation of the gender theory and I recommend a decalogue of interpretative standards which receive its vision. Constitucionalismolegal interpretationperspectiva de géneroestándares interpretativos.interpretive standards 60 89UNESCO::CIENCIAS JURÍDICAS2070-8157 22082 Revista Boliviana de Derecho 565487 2021 31 7730053 La interpretación jurídica con perspectiva de género Un decálogo de estándares interpretativos Juan: Constitucionalismthe gender perspective is an essential condition to make a legal correct interpretation because its postulates influence any notion and course of legal action. On this matterThe Argentine legal system is part of the constitutional paradigm. In this case [Gabriel R.]ConstitucionalismGabriel R. : The Argentine legal system is part of the constitutional paradigm. In this case
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Implications of non standard scenarios in Cosmology and the very early Universe

2014

167 páginas. Tesis Doctoral del Departamento de Física Teórica de la Universidad de Valencia y del Instituto de Física Corpuscular (IFIC).

:FÍSICA [UNESCO]cosmology of theories beyond the standard modelUNESCO::FÍSICAinflationbaryogenesis
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SiPM based tracking for detector calibration in NEXT

2015

197 páginas. Tesis Doctoral del Departamento de Física Atómica, Molecular y Nuclear de la Universidad de Valencia y del Instituto de Física Corpuscular (IFIC).

:FÍSICA::Otras especialidades físicas [UNESCO]Xenon Gas DetectorsExperimento NEXTModelo StandardSilicon PhotoMultipliersFísica de PartículasUNESCO::FÍSICA::Otras especialidades físicasNeutrinoless Double Beta Decay
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Search for a Dark Leptophilic Scalar in e(+) e(-) Collisions

2020

Many scenarios of physics beyond the standard model predict the existence of new gauge singlets, which might be substantially lighter than the weak scale. The experimental constraints on additional scalars with masses in the MeV to GeV range could be significantly weakened if they interact predominantly with leptons rather than quarks. At an e+e- collider, such a leptophilic scalar (φL) would be produced predominantly through radiation from a τ lepton. We report herein a search for e+e-→τ+τ-φL, φL→ℓ+ℓ- (ℓ=e, μ) using data collected by the BABAR experiment at SLAC. No significant signal is observed, and we set limits on the φL coupling to leptons in the range 0.04<mφL<7.0 GeV. These bounds s…

:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Electron–positron annihilationPhysics beyond the Standard ModelGeneral Physics and Astronomy01 natural sciencesElementary particlecurrent: constraintE+e- collider[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]HEP BaBarMathematical physicsPhysicstau: pair productionnew physics: search forSettore FIS/01 - Fisica Sperimentalescale: electroweak interactionelectron positron: colliding beamsModel estàndard (Física nuclear)Standard model (Nuclear physics)Monte Carlo method:Nuclear and elementary particle physics: 431 [VDP]The standard modelConfidence levelPEP-IIAnomalous magnetic momentleptonic decayScalar (mathematics)lepton: couplinganomalycoupling constant: upper limitelectron positron: annihilationNOMagnetic momentBABAR experimentlepton: coupling: high0103 physical sciencesParameter spaceBaBar; PEP-II; Rare decays;singlet: gauge010306 general physicsMètode de Montecarlomuon: magnetic momentHigh Energy Physics::PhenomenologyRare decaysSLAC PEP StorRare decay[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]BaBarElementary Particles and FieldsHigh Energy Physics::ExperimentLeptonexperimental results
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Observation and Measurement of Forward Proton Scattering in Association with Lepton Pairs Produced via the Photon Fusion Mechanism at ATLAS

2020

The observation of forward proton scattering in association with lepton pairs (eþe− þ p or μþμ− þ p) produced via photon fusion is presented. The scattered proton is detected by the ATLAS Forward Proton spectrometer, while the leptons are reconstructed by the central ATLAS detector. Proton-proton collision data recorded in 2017 at a center-of-mass energy of ffiffiffi s p ¼ 13 TeV are analyzed, corresponding to an integrated luminosity of 14.6 fb−1. A total of 57 (123) candidates in the ee þ p (μμ þ p) final state are selected, allowing the background-only hypothesis to be rejected with a significance exceeding 5 standard deviations in each channel. Proton-tagging techniques are introduced f…

:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Photon13000 GeV-cmsLHC ATLASmeasured [channel cross section]General Physics and Astronomy01 natural sciences7. Clean energyHigh Energy Physics - Experimentelectron: pair productionSubatomär fysikHigh Energy Physics - Experiment (hep-ex)Integrated LuminosityFusion Mechanismphoton photon: fusionspectrometer [p]Subatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]scattering [p p]pair production [lepton]Electroweak interactionQuantum ChromodynamicsParticle productionNuclear ExperimentSettore FIS/01PhysicsQuantum chromodynamicsObservation and MeasurementQuantum electrodynamicsLarge Hadron Colliderp: spectrometerdimuonAtlas (topology)COLLISIONS; PHYSICS; GAMMA; LIGHT; LHCElectroweak interactionDetectorphotonATLASfusion [photon photon]muon: pair production:Nuclear and elementary particle physics: 431 [VDP]PhotoproductionLIGHTCERN LHC CollATLAS DetectorsLHCcolliding beams [p p]channel cross section: measuredParticle Physics - Experimentsmall-angleParticle physicsp p: scatteringCOLLISIONSp: particle identificationCiências Naturais::Ciências Físicas530 Physicslepton: pair production:Ciências Físicas [Ciências Naturais]Particles & FieldsFOS: Physical sciencesparticle identification [p]LHC ATLAS High Energy PhysicsPHYSICS0103 physical sciencesddc:530Cross-Section Measurementpair production [electron]pair production [muon]High Energy Physics010306 general physicsCiencias ExactasATLAS CollaborationScience & TechnologySpectrometerhep-exPomeronsFísicaGAMMALeptonsProton Scatteringexclusive productionPrecision measurementsProton Proton CollisionsStandard DeviationExperimental High Energy PhysicsElementary Particles and FieldsHigh Energy Physics::ExperimentHadron-hadron collisionsp p: colliding beamsLeptonacceptanceexperimental results
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Limits on the production of the standard model Higgs boson in pp collisions at root s=7 TeV with the ATLAS detector

2011

A search for the Standard Model Higgs boson at the Large Hadron Collider (LHC) running at a centre-of-mass energy of 7 TeV is reported, based on a total integrated luminosity of up to 40 pb−1 collected by the ATLAS detector in 2010. Several Higgs boson decay channels: H→γγ, H→ZZ(∗)→ℓℓℓℓ, H→ZZ→ℓℓνν, H→ZZ→ℓℓqq, H→WW(∗)→ℓνℓν and H→WW→ℓνqq (ℓ is e, μ) are combined in a mass range from 110 GeV to 600 GeV. The highest sensitivity is achieved in the mass range between 160 GeV and 170 GeV, where the expected 95% CL exclusion sensitivity is at Higgs boson production cross sections 2.3 times the Standard Model prediction. Upper limits on the cross section for its production are determined. Models wit…

:Mathematics and natural science: 400::Physics: 430 [VDP]Physics and Astronomy (miscellaneous)Tevatron:Mathematics and natural science: 400::Physics: 430::Nuclear and elementary particle physics: 431 [VDP]7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentPhysicsLarge Hadron ColliderSettore FIS/01 - Fisica SperimentaleSearchATLASTevatronMassless particleLarge Hadron ColliderPhysical SciencesHiggs bosonComputingMethodologies_DOCUMENTANDTEXTPROCESSINGProduction (computer science)Física nuclearLHCParticle Physics - ExperimentQuarkParticle physicsHiggs bosons; pp collisions; ATLASCiências Naturais::Ciências FísicasHiggs bosonAstrophysics::High Energy Astrophysical Phenomena:Ciências Físicas [Ciências Naturais]FOS: Physical sciencesddc:500.2Massless Particles530Nnlo QCDStandard ModelNuclear physics0103 physical sciencesFysikddc:530High Energy Physics010306 general physicsEngineering (miscellaneous)Ciencias ExactasScience & TechnologyATLAS detectorParton Distributions010308 nuclear & particles physicsProton-proton collisionHigh Energy Physics::PhenomenologyFísicaHadron CollidersExperimental High Energy PhysicsHigh Energy Physics::ExperimentDecaysLeptonEUROPEAN PHYSICAL JOURNAL C
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Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial

2021

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…

A ActionDGOJ Directorate General for the Regulation of GamblingCIDI Composite International Diagnostic InterviewPA Positive AffectSPIRIT Standard Protocol Items Recommendations for Interventional TrialsefficacyPsychological interventionMotivational interviewingGE Gambling ExpectanciesDSM-IV Diagnostic and Statistical Manual of Mental Disorders Fourth EditionOASIS The Overall Anxiety Severity and Impairment Scalelaw.inventionDERS Difficulties in Emotion Regulation ScaleRandomized controlled triallawPANAS The Positive and Negative Affect SchedulePsychologyRCT Randomized Controlled TrialUPPS-P The Short UPPS-P Impulsivity ScaleICD-10 International Statistical Classification of Diseases and Related Health Problems 10th RevisionCognitionT58.5-58.64GRCS-S Gambling-Related Cognitions ScalePC Predictive ControlBF1-990EDBs Emotion Driven BehavioursC ContemplationGSEQ Gambling Self-Efficacy QuestionnaireDSM-5 Diagnostic and Statistical Manual of Mental Disorders Fifth EditionAnxietyAddicció a Internetmedicine.symptomMI Motivational InterviewingPsychologyJocs per ordinadorM Maintenancemedicine.medical_specialtyemotion regulationG-SAS The Gambling Symptom Assessment ScaleEMA Ecological Momentary AssessmentODSIS The Overall Depression Severity and Impairment ScaleEfficacyWL Waiting ListIC Illusion of ControlIB Interpretative BiasMFS Monitoring Feedback and SupportCBTHealth InformaticsInformation technologyCBT Cognitive Behavioral TherapyImpulsivityCONSORT-EHEALTH Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online TelehealthISG Perceived Inability to Stop GamblingQuality of life (healthcare)URICA The University of Rhode Island Change Assessment ScaleIntervention (counseling)medicineGD Gambling DisorderSCID-P The Structured Clinical InterviewPsychiatryQLI Quality Life IndexInternetEmotion regulationFull length ArticleSUS System Usability ScalegamblingEMI Ecological Momentary InterventionMINI Mini International Neuropsychiatric InterviewGI Gambling history interview and current gambling situation and related variables assessmentNA Negative AffectGamblingNODS NORC DSM-IV Screen for Gambling ProblemsPFIs Personal Feedback InterventionsDSM-III-R Diagnostic and Statistical Manual of Mental Disorders 3rd Edition RevisedHADS Hospital Anxiety Depression ScaleinternetP Precontemplation
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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

ABCC1 ATP binding cassette subfamily C member 1IC50 half maximal inhibitory concentrationMultidrug resistancePharmacologyNADPH reduced nicotinamide adenine dinucleotide phosphateF bioavailabilitychemistry.chemical_compoundPCR polymerase chain reaction0302 clinical medicineMDR multidrug resistanceECL electrochemiluminescencet1/2 elimination half-lifeLC–MS liquid chromatography coupled with mass spectrometryN.D. not detectedGeneral Pharmacology Toxicology and PharmaceuticsBBB blood–brain barriermedia_commonATF3 activating transcription factor 30303 health sciencesChemistryABC ATP-binding cassetteNMPA National Medical Products AdministrationPXR pregnane X receptorSDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresisHBSS Hankʹs balanced salt solutionABCB1Combination chemotherapyProdrugMarsdenia tenacissimaCmax peak concentrationPaclitaxelGAPDH glyceraldehyde-3-phosphate dehydrogenase030220 oncology & carcinogenesisBHI brain heart infusionOriginal ArticleAUC0–∞ area under plasma concentration vs. time curveMRT mean residence timeDrugmedia_common.quotation_subjectRM1-950Vd volume of distributionABCB1 ATP binding cassette subfamily B member 1UIC-2 mouse monoclonal ABCB1 antibodyABCG2 ATP binding cassette subfamily G member 2Combination chemotherapyCYP cytochrome P450 isozymePI propidium iodideTEER transepithelial electrical resistance03 medical and health sciencesPBS phosphate buffer salineFBS fetal bovine serumDox doxorubicinIn vivoPOP polyoxypregnanemedicine030304 developmental biologyEVOM epithelial tissue voltohmmeterTmax time for peak concentrationCancerLBE lowest binding energyPE phycoerythrinmedicine.diseaseMultiple drug resistancePolyoxypregnanePapp apparent permeabilityN.A. not applicableCancer cellH&E hematoxylin and eosinMDR1a multidrug resistance protein 1aTherapeutics. PharmacologyqPCR quantitative PCRM. tenacissima Marsdenia tenacissimaCL clearanceSD standard derivationActa Pharmaceutica Sinica B
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