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showing 10 items of 8943 documents

Kardiale MRT : Änderungen der normalisierten myokardialen Gadolinium-Anreicherung über die Zeit nach Kontrastmittelinjektion in Patienten mit akuter …

2011

PURPOSE An increased normalized gadolinium accumulation (NGA) in the myocardium during early washout has been used for the diagnosis of acute myocarditis (AM). Due to the fact that the pharmacokinetics of contrast agents are complex, time-related changes in NGA after contrast injection are likely. Because knowledge about time-related changes of NGA may improve the diagnostic accuracy of MR, our study aimed to estimate the time course of NGA after contrast injection in patients as well as in healthy volunteers. MATERIALS AND METHODS An ECG-triggered inversion recovery SSFP sequence with incrementally increasing inversion times was repetitively acquired over the 15 minutes after injection of …

AdultGadolinium DTPAMalemedicine.medical_specialtymedia_common.quotation_subjectGadoliniumCardiac-Gated Imaging TechniquesMedizinchemistry.chemical_elementContrast MediaSensitivity and SpecificityPharmacokineticsReference ValuesInternal medicineHealthy volunteersmedicineImage Processing Computer-AssistedContrast (vision)HumansRadiology Nuclear Medicine and imagingIn patientMuscle Skeletalmedia_commonbusiness.industryMyocardiumWashoutSteady-state free precession imagingMiddle AgedImage EnhancementMagnetic Resonance ImagingMyocardial ContractionMyocarditischemistryContrast injectionAcute DiseaseInjections IntravenousCardiologyFemalebusiness
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Quantitative criteria for the diagnosis of the congenital absence of pericardium by cardiac magnetic resonance

2015

Congenital absence of the left ventricular pericardium (LCAP) is a rare and poorly known cardiac malformation. Cardiac Magnetic Resonance (CMR) is generally used for the diagnosis of LCAP because of its high soft tissue contrast, multiplanarity and cine capability, but the diagnosis is usually made by only qualitative criteria. The aim of the present study was to establish quantitative criteria for the accurate diagnosis of LCAP on CMR.We enrolled nine consecutive patients affected by LCAP (mean age 26±8years, 7 males), 13 healthy controls, 13 patients with dilated cardiomyopathy (DCM), 12 patients with hypertrophic cardiomyopathy (HCM) and 13 patients with right ventricular overload (RVO).…

AdultHeart Defects CongenitalMalemedicine.medical_specialtyMagnetic Resonance SpectroscopyCardiac magnetic resonanceLeft congenital absence of the pericardium030204 cardiovascular system & hematologyVolume change030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansPericardiumRadiology Nuclear Medicine and imagingcardiovascular diseasesbusiness.industryHealthy subjectsHypertrophic cardiomyopathyReproducibility of ResultsDilated cardiomyopathyMean ageGeneral MedicineSteady-state free precession imagingmedicine.diseasemedicine.anatomical_structurecardiovascular systemCardiologyFemaleRadiologybusinessCardiac magnetic resonancePericardiumHumanEuropean Journal of Radiology
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Cultural and communicational traits of oral health care: results of a Finnish case study.

2006

This paper aims to describe the cultural and communicational traits of Finnish oral health care. First, employees' views and experiences regarding their organization and their position within it are investigated and, second, relations between different individual and organizational factors are analyzed. Finally, a conceptual framework of organizational coherence is constructed.The paper shows that data collection (n = 58, 84 percent response rate) was carried out in 2002 at a Finnish dental clinic by using a semi-structured questionnaire. The data were analyzed statistically by using, among other things, non-parametric tests and a structural equation model (LISREL) and qualitatively by usin…

AdultHierarchy SocialDental AssistantsStructural equation modelingLISRELJob SatisfactionHealth servicesProfessional RoleMedicineDental StaffHumansFinlandResponse rate (survey)Data collectionbusiness.industryHealth PolicyCommunicationDental ClinicsProcess Assessment Health CareMiddle AgedOrganizational CultureBenchmarkingLeadershipDental clinicConceptual frameworkState DentistryOrganizational Case StudiesBusiness Management and Accounting (miscellaneous)Oral health carebusinessSocial psychologyInstitutional PracticeJournal of health organization and management
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Intra‐ and interreader reproducibility of PI‐RADSv2: A multireader study

2018

Background The Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) has been in use since 2015; while interreader reproducibility has been studied, there has been a paucity of studies investigating the intrareader reproducibility of PI-RADSv2. Purpose To evaluate both intra- and interreader reproducibility of PI-RADSv2 in the assessment of intraprostatic lesions using multiparametric magnetic resonance imaging (mpMRI). Study type Retrospective. Population/subjects In all, 102 consecutive biopsy-naive patients who underwent prostate MRI and subsequent MR/transrectal ultrasonography (MR/TRUS)-guided biopsy. Field strength/sequences Prostate mpMRI at 3T using endorectal with phased…

AdultImage-Guided BiopsyMaleIntraclass correlationBiopsyPopulationContrast MediaArticle030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineHumansMedicineRadiology Nuclear Medicine and imagingMultiparametric Magnetic Resonance ImagingStage (cooking)educationMultiparametric Magnetic Resonance ImagingAgedRetrospective StudiesUltrasonographyAged 80 and overObserver VariationReproducibilityeducation.field_of_studymedicine.diagnostic_testbusiness.industryProstateProstatic NeoplasmsReproducibility of ResultsMiddle AgedProstate-Specific AntigenReference StandardsMagnetic Resonance ImagingPI-RADSDiffusion Magnetic Resonance ImagingTransrectal ultrasonographybusinessNuclear medicineAlgorithmsKappaJournal of Magnetic Resonance Imaging
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Psychological and hormonal features of smokers at risk to gain weight after smoking cessation--results of a multicenter study.

2011

Preclinical and clinical data suggest modulating effects of appetite-regulating hormones and stress perception on food intake. Nicotine intake also interferes with regulation of body weight. Especially following smoking cessation gaining weight is a common but only partially understood consequence. The aim of this study was to examine the interaction between smoking habits, the appetite regulating hormone leptin, negative affectivity, and stress vulnerability on eating behavior in a clinical case-control study under standardized conditions. In a large population-based study sample, we compared leptin and cortisol plasma concentrations (radioimmunoassay) between current tobacco smokers with …

AdultLeptinMaleRiskmedicine.medical_specialtyHydrocortisonemedicine.medical_treatmentPerceived Stress ScaleAnxietyWeight GainNegative affectivityNicotineBehavioral NeuroscienceYoung AdultEndocrinologySurveys and QuestionnairesmedicineHumansPsychiatrySalivaEndocrine and Autonomic SystemsSmokingBeck Depression InventoryFeeding BehaviorMiddle AgedCase-Control StudiesSmoking cessationAnxietyFemaleSmoking Cessationmedicine.symptomPsychologyThree-Factor Eating QuestionnaireState-Trait Anxiety InventoryStress PsychologicalClinical psychologymedicine.drugHormones and behavior
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Modeling of Human Posturokinetic Movements by a Linear Feedback System: Relations among Feedback Coefficients

2002

This study describes a method of modeling human trunk and whole body backward bending and suggests a possible neural control strategy. The hypothesis was that the control system can be modeled as a linear feedback system, in which the torque acting at a given joint is a function of the state variables (angular positions and angular velocities). The linear system enabled representation of the feedback system by a gain matrix. The matrix was computed from the kinematics recorded by a movement analysis system and from the joint torques calculated by inverse dynamics. To validate the control model, a comparison was made between the angular kinematics yielded by the model and the experimental d…

AdultMale0209 industrial biotechnologyState variableMovementPostureLinear systemExperimental and Cognitive Psychology02 engineering and technologyKinematicsModels TheoreticalSensory SystemsFeedbackKinesisInverse dynamicsMatrix (mathematics)020901 industrial engineering & automationControl theoryControl system0202 electrical engineering electronic engineering information engineeringHumansTorque020201 artificial intelligence & image processingRepresentation (mathematics)MathematicsPerceptual and Motor Skills
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Cognitive variability in bipolar I disorder: A cluster-analytic approach informed by resting-state data

2019

Abstract Background While the presence of cognitive performance deficits in bipolar disorder I (BD-I) is well established, there is no consensus about which cognitive abilities are affected. Heterogeneous phenotypes displayed in BD-I further suggest the existence of subgroups among the disorder. The present study sought to identify different cognitive profiles among BD-I patients as well as potentially underlying neuronal network changes. Methods 54 euthymic BD-I patients underwent cognitive testing and resting state neuroimaging. Hierarchical cluster-analysis was performed on executive function scores of bipolar patients. The derived clusters were compared against 54 age-, gender- and IQ-m…

AdultMale0301 basic medicineBipolar DisorderBipolar I disorderNeuropsychological TestsImpulsivityExecutive Function03 medical and health sciencesCellular and Molecular NeuroscienceCognition0302 clinical medicineNeural PathwaysmedicineCluster AnalysisHumansBipolar disorderPharmacologyBrain MappingResting state fMRIAction intention and motor controlCognitive flexibilityBrainCognitionmedicine.diseaseExecutive functionsMagnetic Resonance ImagingCognitive test030104 developmental biologyImpulsive BehaviorFemalemedicine.symptomPsychology030217 neurology & neurosurgeryCognitive psychology
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Growth hormone replacement in adults:Real-world data from two large studies in US and Europe

2020

Objective: This report describes the effectiveness and safety of growth hormone replacement in 3180 adult patients with growth hormone deficiency followed-up for 0.0–12.2 years in two completed, complementary, non-interventional, multicentre studies, NordiNet® International Outcome Study (IOS) (NCT00960128) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program (NCT01009905). Design: In both studies, Norditropin® (somatropin; Novo Nordisk A/S, Denmark) was administered at the discretion of the treating physician and according to routine practice. We present data on baseline characteristics, growth hormone dose, safety data and change from baseline in waist circumferenc…

AdultMale0301 basic medicineIGF-I SDSPediatricsmedicine.medical_specialtyWaistHormone Replacement TherapyEndocrinology Diabetes and MetabolismANSWER Program030209 endocrinology & metabolismEffectivenessGrowth hormoneNordiNet® International Outcome Study (IOS)Body compositionHypopituitarismBody Mass IndexGrowth hormone deficiency03 medical and health sciences0302 clinical medicineEndocrinologyElectric ImpedancemedicineHumansGrowth hormone replacementAgedAdult patientsHuman Growth Hormonebusiness.industryMiddle Agedmedicine.diseaseRecombinant ProteinsUnited StatesReal-world dataEuropeClinical Practice030104 developmental biologyGrowth hormone deficiency in adultsBaseline characteristicsBody CompositionFemaleWaist CircumferenceSafetybusinessReal world dataBody mass index
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Carriage of Enterobacteria Producing Extended-Spectrum β-Lactamases and Composition of the Gut Microbiota in an Amerindian Community

2015

ABSTRACT Epidemiological and individual risk factors for colonization by enterobacteria producing extended-spectrum beta-lactamases (E-ESBL) have been studied extensively, but whether such colonization is associated with significant changes in the composition of the rest of the microbiota is still unknown. To address this issue, we assessed in an isolated Amerindian Guianese community whether intestinal carriage of E-ESBL was associated with specificities in gut microbiota using metagenomic and metatranscriptomic approaches. While the richness of taxa of the active microbiota of carriers was similar to that of noncarriers, the taxa were less homogeneous. In addition, species of four genera,…

AdultMale0301 basic medicinefood.ingredient030106 microbiologyGene ExpressionGut floradigestive systembeta-LactamasesCoprococcusMicrobiologyFeces03 medical and health sciencesfluids and secretionsfoodEnterobacteriaceaeMechanisms of ResistancePhylogeneticsRNA Ribosomal 16SHumansPharmacology (medical)ColonizationPhylogenyAgedPharmacologybiologyEnterobacteriaceae InfectionsSequence Analysis DNAMiddle Agedbiology.organism_classificationParabacteroidesDesulfovibrioEnterobacteriaceaeFrench GuianaGastrointestinal Microbiomestomatognathic diseasesInfectious DiseasesGenes BacterialMetagenomicsCarrier StateIndians North AmericanbacteriaMetagenomeDesulfovibrioFemaleTranscriptomeAntimicrobial Agents and Chemotherapy
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Psychometric properties of measures of sociocultural influence and internalization of appearance ideals across eight countries

2020

The aim of the current study was to examine the psychometric properties of two well-established measures of sociocultural influence and internalization of the thin/low body fat ideal and muscular ideal. Data from 6272 emerging adults (68.9 % female), aged 18-30 years from Australia, Belgium, Canada, China, Italy, Japan, Spain, and the U.S. were included in this study. Participants completed measures of pressure from mother, fathers, peers, and media, to both increase muscles and lose weight, as well as internalization of the thin/low body fat ideal and muscular ideal. Overall, support for partial invariance was found across the scales. In addition, group level differences were found between…

AdultMale050103 clinical psychologyCanadaChinaSocial PsychologyAdolescentPsychometricsmedia_common.quotation_subjectMothers050109 social psychologySettore M-PSI/08 - PSICOLOGIA CLINICAPeer GroupDevelopmental psychologyBody Mass Index[SHS]Humanities and Social SciencesYoung AdultSex FactorsBelgiumJapanSurveys and QuestionnairesHumans0501 psychology and cognitive sciences10. No inequalitySociocultural evolutionInternalizationGroup levelSocioeconomic statusGeneral PsychologyApplied Psychologymedia_commonIdeal (set theory)05 social sciencesBody WeightAge FactorsAustraliaUnited StatesSociocultural influenceBody imageItalySpainFemalePsychologyBody mass indexInternalizationPressures
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