Search results for "Stationarity"

showing 9 items of 9 documents

Multiple steady states and the form of response functions to antigen in a model for the initiation of T cell activation

2017

The aim of this paper is to study the qualitative behaviour predicted by a mathematical model for the initial stage of T-cell activation. The state variables in the model are the concentrations of phosphorylation states of the T-cell receptor (TCR) complex and the phosphatase SHP-1 in the cell. It is shown that these quantities cannot approach zero and that the model possesses more than one positive steady state for certain values of the parameters. It can also exhibit damped oscillations. It is proved that the chemical concentration which represents the degree of activation of the cell, that of the maximally phosphorylated form of the TCR complex, is, in general, a non-monotone function of…

0301 basic medicineState variable1004T cellMolecular Networks (q-bio.MN)PhosphatasemultistationarityDynamical Systems (math.DS)24Dissociation (chemistry)immunology03 medical and health sciences119medicineFOS: Mathematics1008Quantitative Biology - Molecular NetworksMathematics - Dynamical Systemslcsh:ScienceReceptort cellsMultidisciplinaryChemistryT-cell receptor92C37Dissociation constant030104 developmental biologymedicine.anatomical_structureFOS: Biological sciencesBiophysicsPhosphorylationlcsh:QMathematicsResearch Article
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The Global Side of the Investments-Savings Puzzle

2008

In this paper we re-examine the long standing and puzzling correlation between national savings and investment in industrial countries. We apply an econometric methodology that allows us to separate idiosyncratic correlation at the country level from correlation at the global level. In a major break with the existing literature, we find no evidence of a long run relationship in the idiosyncratic components of savings and investment. We also find that the global components in savings and investments commove, indicating that they react to shocks of a global nature.

Savings Investment Feldstein-Horioka Puzzle Panel Nonstationarity Principal Components.jel:C31jel:F32jel:C33jel:F41
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Time-Varying Surrogate Data to Assess Nonlinearity in Nonstationary Time Series: Application to Heart Rate Variability

2009

We propose a method to extend to time-varying (TV) systems the procedure for generating typical surrogate time series, in order to test the presence of nonlinear dynamics in potentially nonstationary signals. The method is based on fitting a TV autoregressive (AR) model to the original series and then regressing the model coefficients with random replacements of the model residuals to generate TV AR surrogate series. The proposed surrogate series were used in combination with a TV sample entropy (SE) discriminating statistic to assess nonlinearity in both simulated and experimental time series, in comparison with traditional time-invariant (TIV) surrogates combined with the TIV SE discrimin…

AdultTime FactorsComputer scienceRestBiomedical EngineeringSurrogate dataHeart RateStatisticsHumansHeart rate variabilityEntropy (information theory)Computer SimulationNonstationarityEntropy (energy dispersal)Time seriesEntropy (arrow of time)StatisticModels StatisticalEntropy (statistical thermodynamics)RespirationNonlinear dynamicModels CardiovascularComplexitySample entropyNonlinear systemNonlinear DynamicsAutoregressive modelSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaSurrogate dataTime-varying (TV) autoregressive (AR) modelHeart rate variability (HRV)AlgorithmsEntropy (order and disorder)IEEE Transactions on Biomedical Engineering
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Testing for external sustainability under a monetary integration process. Does the Lawson doctrine apply to Europe?

2015

Monetary integration, and more specifically, the creation of a monetary union in Europe, raises new economic questions concerning its functioning and governance. In particular, we focus on the implications of high and persistent current account deficits for the economic performance of monetary union members in the medium term. Recent literature has argued that conventional measures of external sustainability are misleading because they omit the effects of capital variations on net foreign asset positions due to, among others, stock or debt market crises. In this paper we revisit external sustainability making use of the database developed by Lane and Milesi-Ferretti (2007) that includes the…

EMUMacroeconomicsEconomics and EconometricsValuation effectsCorporate governancemedia_common.quotation_subjectDoctrineMonetary integrationMedium termSustainabilityCross-section dependenceEconomicsStructural breaksBond marketCurrent account imbalancesPanel stationarityStock (geology)media_commonEconomic Modelling
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EMERGENCE OF TRAVELLING WAVES IN SMOOTH NERVE FIBRES

2008

International audience; An approximate analytical solution characterizing initial condi- tions leading to action potential ¯ring in smooth nerve ¯bres is determined, using the bistable equation. In the ¯rst place, we present a non-trivial sta- tionary solution wave. Then, we extract the main features of this solution to obtain a frontier condition between the initiation of the travelling waves and a decay to the resting state. This frontier corresponds to a separatrix in the projected dynamics diagram depending on the width and the amplitude of the stationary wave.

StationarityBistability[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS][ MATH.MATH-DS ] Mathematics [math]/Dynamical Systems [math.DS][ NLIN.NLIN-CD ] Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD][MATH.MATH-DS] Mathematics [math]/Dynamical Systems [math.DS]01 natural sciencesNerve fibresStanding waveOptics[ MATH.MATH-AP ] Mathematics [math]/Analysis of PDEs [math.AP]0103 physical sciencesTraveling wave[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP]Discrete Mathematics and Combinatorics[MATH.MATH-AP] Mathematics [math]/Analysis of PDEs [math.AP]0101 mathematics010306 general physicsProjected dynamicsPhysicsSeparatrixbusiness.industry[SCCO.NEUR]Cognitive science/NeuroscienceApplied Mathematics[SCCO.NEUR] Cognitive science/NeuroscienceDiagramDynamics (mechanics)Mechanics010101 applied mathematics[NLIN.NLIN-CD] Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD]Amplitude[NLIN.NLIN-CD]Nonlinear Sciences [physics]/Chaotic Dynamics [nlin.CD][ SCCO.NEUR ] Cognitive science/NeuroscienceAction potential firingbusinessAnalysis
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The Global Side of the Investment-Saving Puzzle

2009

In this paper, we reexamine the long-standing and puzzling correlation between national saving and investment in industrial countries. We apply an econometric methodology that allows us to separate idiosyncratic correlation at the country level from correlation at the global level. In a major break with the existing literature, we find no evidence of a long-run relationship in the idiosyncratic components of saving and investment. We also find that the global components in saving and investments commove, indicating that they react to shocks of a global nature.

MacroeconomicsConsumption [Macroeconomics]Economics and EconometricsSavingFeldstein–Horioka puzzlesaving • investment • Feldstein–Horioka puzzle • panel nonstationarity • principal componentsCapitalInvestment (macroeconomics)Country levelAccountingCapital (economics)Wealth E210Capacity E220EconomicsInvestmentFinanceProduction E230 [Macroeconomics]
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Unsupervised representation learning of spontaneous MEG data with nonlinear ICA

2023

Funding Information: We wish to thank the reviewers and editors for the useful comments to improve the paper a lot. We thank Dr. Hiroshi Morioka for the useful discussion at the beginning of the project. L.P. was funded in part by the European Research Council (No. 678578 ). A.H. was supported by a Fellowship from CIFAR, and the Academy of Finland. The authors acknowledge the computational resources provided by the Aalto Science-IT project, and also wish to thank the Finnish Grid and Cloud Infrastructure (FGCI) for supporting this project with computational and data storage resources. | openaire: EC/H2020/678578/EU//HRMEG Resting-state magnetoencephalography (MEG) data show complex but stru…

neuropalautenon-stationarityMEGsignaalinkäsittelyCognitive Neurosciencesyväoppiminensignaalianalyysineurofeedbackunsupervised learningdeep generative modelkoneoppiminenNeurologyresting-state networkmagnetoencephalography (MEG)nonlinear independent component analysis (ICA)NeuroImage
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The Use of GAMLSS Framework for a Non-Stationary Frequency Analysis of Annual Runoff Data over a Mediterranean Area

2022

Climate change affects all the components of the hydrological cycle. Starting from precipitation distribution, climate alterations have direct effects on both surface water and groundwater in terms of their quantity and quality. These effects lead to modifications in water availability for agriculture, ecology and other social uses. Change in rainfall patterns also affects the runoff of natural rivers. For this reason, studying runoff data according to classical hydrological approaches, i.e., statistical inference methods that exploit stationary probability distributions, might result in missing important information relevant to climate change. From this point of view, a new approach has to…

GAMLSSNon-stationaritySettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaGeography Planning and DevelopmentrunoffAquatic Sciencefrequency analysirainfall–runoff modelBiochemistrynon-stationarity; GAMLSS; runoff; frequency analysis; rainfall–runoff modelWater Science and TechnologyWater
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ANALYTICAL DETERMINATION OF INITIAL CONDITIONS LEADING TO FIRING IN NERVE FIBERS

2007

International audience; An analytical solution characterizing initial conditions leading to action potential firing in smooth nerve fibers is determined, using the bistable equation. In the first place, we present a nontrivial stationary solution wave, then, using the perturbative method, we analyze the stability of this stationary wave. We show that it corresponds to a frontier between the initiation of the travelling waves and a decay to the resting state. Eventually, this analytical approach is extended to FitzHugh-Nagumo model.

StationarityBistability[PHYS.MPHY]Physics [physics]/Mathematical Physics [math-ph][MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS][ MATH.MATH-DS ] Mathematics [math]/Dynamical Systems [math.DS][MATH.MATH-DS] Mathematics [math]/Dynamical Systems [math.DS]01 natural sciencesStability (probability)010305 fluids & plasmasStanding waveOptics[MATH.MATH-MP]Mathematics [math]/Mathematical Physics [math-ph]0103 physical sciencesReaction–diffusion systemTraveling wave[MATH.MATH-MP] Mathematics [math]/Mathematical Physics [math-ph]0101 mathematicsEngineering (miscellaneous)PhysicsQuantitative Biology::Neurons and Cognitionbusiness.industry[SCCO.NEUR]Cognitive science/Neurosciencenerve fibersApplied Mathematics[SCCO.NEUR] Cognitive science/Neurosciencereaction-diffusion[ MATH.MATH-MP ] Mathematics [math]/Mathematical Physics [math-ph]Mechanics[PHYS.MPHY] Physics [physics]/Mathematical Physics [math-ph]010101 applied mathematicsModeling and Simulation[ SCCO.NEUR ] Cognitive science/Neuroscience[ PHYS.MPHY ] Physics [physics]/Mathematical Physics [math-ph]Action potential firingbusinessStationary solutionnerve fibers.International Journal of Bifurcation and Chaos
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