Search results for "Steri"

showing 10 items of 2646 documents

Tas1R1-Tas1R3 taste receptor variants in human fungiform papillae.

2009

International audience; Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in mice other candidate receptors have been put forward for which a clear role in detection is still lacking. This work was aimed at investigating the molecular determinants underlying umami taste detection in humans. First, we show evidence supporting expression of Tas1R1 and Tas1R3 but not mGluRs in the fungiform papillae of several individuals. Next, we report a number of naturally occurring l-glutamate taste receptor var…

AdultMaleTasteTASTE RECEPTORSGlutamic AcidSNPFUNGIFORM PAPILLAEUmamiBiologyLigandsReceptors Metabotropic GlutamatePolymorphism Single NucleotideReceptors G-Protein-CoupledTAS1R103 medical and health sciencesGLUTAMATE0302 clinical medicineTAS1R3Allosteric RegulationTongueTaste receptorHumansProtein IsoformsMSG030304 developmental biologyAgedGenetics0303 health sciencesBinding SitesGeneral Neuroscience[SCCO.NEUR]Cognitive science/NeuroscienceGenetic VariationHUMANMiddle AgedTaste BudsProtein Structure TertiaryTAS2R38BiochemistryTasteTaste Threshold[ SCCO.NEUR ] Cognitive science/NeuroscienceMetabotropic glutamate receptor 1Ionotropic glutamate receptorFemaleUNAMI030217 neurology & neurosurgery
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Do palatal implants remain positionally stable under orthodontic load? A clinical radiologic study.

2009

Introduction The aim of this study was to determine the positional stability and success rate of palatally placed length-reduced temporary anchorage devices (LRTADs) (length, 4 or 6 mm). Methods Twenty-two patients (ages, 21-62 years; 14 women, 8 men) were enrolled in the study. Each received 1 LRTAD (Orthosystem, Straumann, Switzerland) placed in the midsagittal palate for multifunctional anchorage tasks. Standardized cephalograms were taken directly after implant placement and at the end of treatment to analyze any implant movements. The cephalometric tracings were superimposed on anterior nasal spine to posterior nasal spine in posterior nasal spine to analyze changes in implant angulati…

AdultMaleTime FactorsTooth Movement TechniquesCephalometryBone ScrewsDentistryOrthodonticsOsseointegrationWeight-BearingYoung AdultOsseointegrationmedicineOrthodontic Anchorage ProceduresHumansOrthodontic Appliance DesignLongitudinal StudiesOrthodonticsDental Implantsbusiness.industryPalateDental Implantation EndosseousAnterior nasal spineCraniometryMiddle Agedmedicine.diseaseOrthodontic Anchorage ProceduresRadiographymedicine.anatomical_structureMaxillaFemaleImplantStress MechanicalMalocclusionPosterior nasal spinebusinessMalocclusionAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
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Repetitive transcranial magnetic stimulation over the left parietal cortex facilitates visual search for a letter among its mirror images

2015

Interference by task irrelevant information is seen in visual search paradigms using letters. Thus, it is harder to find the letter 'N' among its mirror reversals 'Icyrillic' than vice versa. This observation, termed the reversed letter effect, involves both a linguistic association and an interference of task irrelevant information - the shape of 'N' or 'Icyrillic' is irrelevant, the search requires merely distinguishing the tilts of oblique bars. We adapted the repetitive transcranial magnetic stimulation (rTMS) methods that we previously used, and conducted three rTMS experiments using healthy subjects. The first experiment investigated the effects of rTMS on the left and right posterior…

AdultMaleTop-down attentionMirror imagemedicine.medical_treatmentCognitive NeuroscienceBiophysicsPosterior parietal cortexRTMSExperimental and Cognitive PsychologyVisual systemTranscranial Direct Current StimulationFunctional LateralityParietal cortexYoung AdultBehavioral NeuroscienceArts and Humanities (miscellaneous)Parietal LobeReaction TimemedicineHumansVentral occipito-temporal cortexAttentionVisual PathwaysAnterior cingulate cortexVisual searchAnalysis of VarianceTranscranial direct-current stimulationSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaParietal lobeElectroencephalographyReversed letterTranscranial magnetic stimulationVisual search asymmetriemedicine.anatomical_structureFemalePsychologyNeurosciencePhotic StimulationCognitive psychology
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Impairments in top down attentional processes in right parietal patients: Paradoxical functional facilitation in visual search

2014

AbstractIt is well known that the right posterior parietal cortex (PPC) is involved in attentional processes, including binding features. It remains unclear whether PPC is implicated in top-down and/or bottom-up components of attention. We aim to clarify this by comparing performance of seven PPC patients and healthy controls (HC) in a visual search task involving a conflict between top-down and bottom-up processes. This task requires essentially a bottom-up feature search. However, top-down attention triggers feature binding for object recognition, designed to be irrelevant but interfering to the task. This results in top-down interference, prolonging the search reaction time. This interfe…

AdultMaleTop-down attentiongenetic structuresmedicine.medical_treatmentPosterior parietal cortexbehavioral disciplines and activities050105 experimental psychologyParietal cortexTask (project management)03 medical and health sciences0302 clinical medicineParietal LobemedicineHumans0501 psychology and cognitive sciencesAttentionVisual searchParietal patientsSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaBrain NeoplasmsVisual search05 social sciencesCognitive neuroscience of visual object recognitionTop-down and bottom-up designMiddle AgedSensory SystemsTranscranial magnetic stimulationStrokeOphthalmologyFeature (computer vision)Case-Control StudiesParadoxical functional facilitationFacilitationVisual PerceptionFemalePsychologyNeuroscience030217 neurology & neurosurgeryPhotic Stimulationpsychological phenomena and processesCognitive psychologyBottom-up attentionVision Research
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Metric assessment of the "mastoid triangle" for sex determination: a validation study.

2006

Recently, a metric approach to skeletal sex determination was published by Paiva and Segre which is based on the summation of two triangular areas defined by three distinct craniometric landmarks: Porion, Mastoidale, and Asterion. According to the authors, values for the total triangle > or =1447.40 mm(2) are characteristic for male crania, while values < or =1260.36 mm(2) are indicative of female skulls (95% confidence). In order to evaluate the method's validity, two sex- and age-documented samples of different provenience were analyzed (N=197). The results show that while the indicated measurements display significant sex differences, the technique is of little practical meaning where a …

AdultMaleValidation studyCephalometryPathology and Forensic MedicineStatisticsGeneticsmedicineHumansMathematicsSex CharacteristicsCraniabiologyForensic anthropologyDiscriminant AnalysisTemporal BoneCraniometrybiology.organism_classificationSexual dimorphismmedicine.anatomical_structureAsterionMetric SystemForensic AnthropologyFemaleMetric (unit)DemographySex characteristicsJournal of forensic sciences
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Exploring the relationship between semantics and space

2009

The asymmetric distribution of human spatial attention has been repeatedly documented in both patients and healthy controls. Biases in the distribution of attention and/or in the mental representation of space may also affect some aspects of language processing. We investigated whether biases in attention and/or mental representation of space affect semantic representations. In particular, we investigated whether semantic judgments could be modulated by the location in space where the semantic information was presented and the role of the left and right parietal cortices in this task. Healthy subjects were presented with three pictures arranged horizontally (one middle and two outer picture…

AdultMaleVisual perceptionmedia_common.quotation_subjectPosterior parietal cortexlcsh:MedicineSemanticsLateralization of brain functionNOYoung AdultSemantic similarityParietal LobeSEMANTICSPerceptionHumansSPACEAttentionlcsh:ScienceLanguagemedia_commonNeuroscience/Cognitive NeuroscienceAnalysis of VarianceBrain MappingNeuroscience/Behavioral NeuroscienceMultidisciplinarySettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicalcsh:RParietal lobeNeuroscience/Experimental PsychologySpace PerceptionVisual PerceptionMental representationFemalePerceptionlcsh:QPsychologyResearch ArticleCognitive psychology
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Metabolic and structural connectivity within the default mode network relates to working memory performance in young healthy adults.

2012

Abstract Studies of functional connectivity suggest that the default mode network (DMN) might be relevant for cognitive functions. Here, we examined metabolic and structural connectivity between major DMN nodes, the posterior cingulate (PCC) and medial prefrontal cortex (MPFC), in relation to normal working memory (WM). DMN was captured using independent component analysis of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) data from 35 young healthy adults (27.1 ± 5.1 years). Metabolic connectivity, a correlation between FDG uptake in PCC and MPFC, was examined in groups of subjects with (relative to median) low (n = 18) and high (n = 17) performance on digit span backward te…

AdultMaleWorking memoryCognitive NeuroscienceBrainCognitionHealthy VolunteersCorrelationMemory Short-TermNeurologyFluorodeoxyglucose F18Posterior cingulatePositron-Emission TomographyMemory spanConnectomeHumansFemaleNerve NetRadiopharmaceuticalsPrefrontal cortexPsychologyNeuroscienceDefault mode networkDiffusion MRISignal TransductionNeuroImage
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Posterior interosseous nerve of the elbow at the arcade of Frohse: Ultrasound appearance in asymptomatic subjects

2019

PURPOSE To assess the normal values of the antero-posterior (AP) diameter of the posterior interosseous nerve (PIN) of the elbow as it passes beneath the arcade of Frohse and to search for PIN-diameter differences between the upstream, entry point and downstream of the arcade. MATERIAL AND METHODS Thirty asymptomatic patients prospectively underwent bilateral B-mode ultrasound of the PIN of the elbow. There were 15 men and 15 women with a mean age of 30.2±5.31 (SD) years (range: 26-43 years). Of these, 23 patients were right-handers (23/30; 77%) and 7 were left handers (7/30; 23%). AP diameter of the PIN was measured in long axis at three different locations including the entry point of the…

AdultMale[SDV]Life Sciences [q-bio]ElbowNormal valuesAsymptomatic030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineElbowmedicineHumansSupinator muscleRadiology Nuclear Medicine and imagingProspective StudiesUltrasonographyLeft handedRadiological and Ultrasound Technologybusiness.industryNerve Compression SyndromesUltrasoundPeripheral Nervous System DiseasesMean ageGeneral MedicineAnatomyPosterior interosseous nervemedicine.anatomical_structure030220 oncology & carcinogenesisAsymptomatic DiseasesFemaleRadial Nervemedicine.symptombusiness
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Effects of valence and arousal on implicit approach/ avoidance tendencies: A fMRI study.

2018

To date, it is still a matter of debate, whether valence or valence and arousal interactively foster implicit approach and avoidance tendencies, and which neural circuitries underlie these effects. To address these questions, we investigated the effects of valence and arousal on implicit approach/avoidance tendencies during fMRI in healthy volunteers (N=46). The implicit approach of positive social scenes was associated with shorter response preparation times and increased activation of the lingual, parahippocampal and fusiform gyri. Valence and arousal did not influence reaction times interactively, but we observed increased activation of prefrontal, motor, temporal, middle cingulate and p…

AdultMalegenetic structuresCognitive NeuroscienceEmotionsPosterior parietal cortexExperimental and Cognitive PsychologyNeuropsychological Tests050105 experimental psychologyArousal03 medical and health sciencesBehavioral NeuroscienceYoung Adult0302 clinical medicineHealthy volunteersHumans0501 psychology and cognitive sciencesValence (psychology)Brain MappingMotivationFunctional Neuroimaging05 social sciencesBrainMiddle AgedMagnetic Resonance ImagingFacilitationFemalePsychologyArousalpsychological phenomena and processes030217 neurology & neurosurgeryPhotic StimulationCognitive psychologyNeuropsychologia
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Direction‐dependent visual cortex activation during horizontal optokinetic stimulation (fMRI study)

2005

Looking at a moving pattern induces optokinetic nystagmus (OKN) and activates an assembly of cortical areas in the visual cortex, including lateral occipitotemporal (motion‐sensitive area MT/V5) and adjacent occipitoparietal areas as well as ocular motor areas such as the prefrontal cortex, frontal, supplementary, and parietal eye fields. The aim of this functional MRI (fMRI) study was to investigate (1) whether stimulus direction‐dependent effects can be found, especially in the cortical eye fields, and (2) whether there is a hemispheric dominance of ocular motor areas. In a group of 15 healthy subjects, OKN in rightward and leftward directions was visually elicited and statistically compa…

AdultMalegenetic structuresEye MovementsMotion PerceptionPosterior parietal cortexNystagmusStimulus (physiology)Functional LateralityOrientationParietal LobemedicineHumansRadiology Nuclear Medicine and imagingVisual PathwaysPrefrontal cortexNystagmus OptokineticResearch ArticlesVisual CortexBrain MappingRadiological and Ultrasound Technologymedicine.diagnostic_testEye movementOptokinetic reflexMagnetic Resonance Imagingeye diseasesFrontal LobeVisual cortexmedicine.anatomical_structureNeurologyOculomotor MusclesSpace PerceptionFemaleNeurology (clinical)Anatomymedicine.symptomNerve NetPsychologyFunctional magnetic resonance imagingNeurosciencePhotic Stimulation
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