Search results for "Storm"

Strategies for Improving Optimal Positioning of Quality Sensors in Urban Drainage Systems for Non-Conservative Contaminants

2021

In the urban drainage sector, the problem of polluting discharges in sewers may act on the proper functioning of the sewer system, on the wastewater treatment plant reliability and on the receiving water body preservation. Therefore, the implementation of a chemical monitoring network is necessary to promptly detect and contain the event of contamination. Sensor location is usually an optimization exercise that is based on probabilistic or black-box methods and their efficiency is usually dependent on the initial assumption made on possible eligibility of nodes to become a monitoring point. It is a common practice to establish an initial non-informative assumption by considering all network…

Coagulation disorders in SARS-CoV-2 infection

2020

A better understanding of the pathogenetic mechanisms triggered by SARS-CoV-2 infection may contribute to a more effective management of patients with COVID-19. Coagulation dysfunction is a key pathogenetic element of this disease as well as a challenge for practitioners. Marked inflammatory process found in severe forms of COVID-19, the complement activation, the cytokine storm, and disruption of the renin-angiotensin-aldosterone system are involved in the onset of thrombotic microangiopathy and large vessel coagulopathy. Virus-induced procoagulant activity occurs at the systemic level. Intravascular microthrombi disrupt vascularization in various tissues and organs, contributing to the oc…

Exploring Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors for Organ Protection in COVID-19

2020

Hospital admissions and mortality from the Coronavirus disease 2019 (COVID-19) pandemic are spreading throughout the world, and second and third waves are thought to be likely. Risk factors for severe COVID-19 include diabetes, chronic kidney disease and cardiovascular disease. Currently, there is no vaccine and no approved therapy. Therapeutic approaches are aimed at preventing viral replication and spread, limiting the impact of the inflammatory overdrive (cytokine storm), preventing thromboembolic complications and replacing or supporting organ function. However, despite organ support, mortality is currently 65% for those receiving advanced respiratory support and 78% for those requiring…

The value of total thyroidectomy as the definitive treatment for Graves’ disease: A single centre experience of 594 cases

2019

Highlights • Total thyroidectomy is a safe and effective treatment for Graves’ disease. • It is associated with a very low incidence rate of post-operative complications. • Total thyroidectomy offers a rapid and definitive control of hyperthyroidism and its related symptoms.

2020

The biological anakinra appears promising to halt cytokine storm syndrome seen in severe courses of COVID-19. However, immunosuppression with anakinra may facilitate sepsis, necessitating continuous screening for bacterial superinfections.

An Overview of Asthma and COVID-19: Protective Factors Against SARS-COV-2 in Pediatric Patients.

2021

Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by severe acute respiratory syndrome coronavirus SARS-COV-2. Aberrant innate immunity response and cytokine storm are responsible for the syndrome. Apparently, in asthmatic patients, the inadequate antiviral immune response and the tendency for asthma exacerbation evoked by common respiratory viruses could explain increased susceptibility to SARS-COV-2 infection. However, asthma has not been suggested to be a risk factor in COVID-19 patients. Therefore, in asthmatic patients some potential protective mechanisms against SARS-COV-2 have been hypothesized, like type 2 immune response, number of eosinophils, overproduct…

USING HIGH RESOLUTION RAINGAUGE DATA FOR STORM TRACKING ANALYSIS IN THE URBAN AREA OF PALERMO, ITALY

2009

This paper presents a comparative analysis between rain-gauge storm tracking techniques in order to achieve a better knowledge of the rainfall dynamics over an urbanized area. The temporal and spatial distribution and kinematics of short term rainfall are recognized as one of the most important reasons in error production in rainfall-runoff on urban catchments. The uncertainty due to rainfall variability can greatly affect urban drainage modeling performance and reliability thus reducing the confidence of operators in their results. Modeling representations of urban catchments and drainage systems are commonly adopted for surface flooding forecasting and management and an adequate knowledge…

FROM A COLLABORATIVE DESIGNING OF STORYTELLING TO A ROBOTIC AND VIRTUAL WORLD REPRESENTATION

2012

This paper presents an experiential learning lab focused on building a digital storytelling using both robots with LEGO Mindstorms and virtual worlds with Kodu Game Lab. The experiential laboratory (32 hours) has involved 33 children of secondary schools in a collaborative learning setting in formal (school labs) and informal learning context (external cultural association). In a first phase of the activity children used Lego Mindstorm robotic kits, assembling them and creating a physical environment (pasterboard arenas) where robots were programmed for moving and taking actions. In a second phase children were invited to transfer the physical world built for robots in a new digital storyte…

Effects of low laser level therapy in rehabilitation of patients with COVID19 pneumonia

2021

Introduction. An unprecedented public health crisis has been triggered worldwide by SARS-CoV-2’s high contagiosity and it’s mortality rates of 1-5%. Although the majority of COVID-19 cases have a good outcome, there is a small percentage that develop severe pneumonia and citokine storm and may be in the need of mechanical ventilation. Methods. Identifying the exact drivers of the excessive inflammation and the biomarkers that can predict a hyperinflammatory response to SARS-CoV-2 would be extremly helpful in finding efficient anti-inflammatory interventions that may stop the progression to acute respiratory distress syndrome (ARDS). Results. In the search for such interventions we have iden…

Modelling urban stormwater impact mitigation by using bmps and storage tanks

2005

The continuous growth of urban areas and the increasing public awareness about environmental impact of stormwater raised high interest on quality impact on the receiving water bodies. Indeed, in the last decades, large efforts have been provided for improving urban drainage systems in order to mitigate environmental impacts. In the present paper, a simplified modelling approach has been developed in order to evaluate the mitigation efficiency of different BMP schemes including infiltration and storage facilities and both considering possible distributed controls and centralised structures. The main goals of the research are the simulation of BMP efficiency in different operational condition…