Search results for "Strategy"
showing 10 items of 2256 documents
The mutual relationship between heart failure and atrial fibrillation
2020
Atrial fibrillation (AF) and heart failure (HF) are evolving epidemies, together responsible for substantial human suffering and health-care expenditure. The simultaneous co-hexistence of the two conditions is associated with mortality rates higher than those observed in individuals with only one or none of them. Patients with concomitant HF and AF suffer from even worse symptoms and poorer prognosis, yet evidence-based evaluation and management of this group of patients is lacking. In this review, we evaluate the common mechanisms for the development of AF in HF patients and vice versa, focusing on the evidence for potential treatment strategies. Recent data have suggested that these patie…
New organisation for follow-up and assessment of treatment efficacy in sleep apnoea.
2019
Obstructive sleep apnoea (OSA) is a highly prevalent disease, and there is an increased demand for OSA diagnosis and treatment. However, resources are limited compared with the growing needs for OSA diagnosis and management, and alternative strategies need to be developed to optimise the OSA clinical pathway. In this review, we propose a management strategy for OSA, and in general for sleep-disordered breathing, to be implemented from diagnosis to follow-up. For this purpose, the best current options seem to be: 1) networking at different levels of care, from primary physicians to specialised sleep laboratories; and 2) use of telemedicine. Telemedicine can contribute to the improved cost-ef…
Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience
2015
Maurizio Vignola was a superb and innovative researcher, who wrote seminal papers on the biology of airway epithelium in asthma. Inflammation and remodelling were the main topics of his research, mostly conducted in biopsy specimens from patients with asthma of variable severity, encompassing the entire spectrum of the disease from mild to severe asthma. His observations contributed to define the biology of asthma as we know it today, and opened the way to the personalised treatment of asthma. His group has successfully continued to investigate the biology and clinical aspects of bronchial asthma, with major interest in the clinical use of biomarkers to monitor disease activity, and in the …
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B…
2016
Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organizatio…
An optimal operating strategy for combined RES–based Generators and Electric Storage Systems for load shifting applications
2013
This paper focuses on an optimal operating strategy of combined RES-based generators and electric storage systems for small/medium-scale public facilities. The operating strategy can be used in load shifting applications in response to a time-of-use (TOU) rate design with differential pricing for on- and off-peak usage. Load shifting applications can be exploited by customers using battery energy storage systems (BESS) in order to reduce their electricity bill, charging the storage when off-peak time periods are applied and discharging it during on-peak periods, when electricity energy prices are high. The operating strategy is implemented within a bidirectional converter that provides an i…
A Study of the Coevolution of Digital Organisms with an Evolutionary Cellular Automaton
2021
This article belongs to the Section Evolutionary Biology.
Governance models of coopetition and innovation: the case of Spanish firms
2016
Although numerous studies show that cooperation relates strongly to obtaining benefits in business innovation, few researchers have considered the role of competition in this relationship. Nevertheless, it is expected that firms can boost their innovation if they cooperate with competitors and with intermediaries. The aim of this study was to observe whether coopeting firms achieve high degrees of innovation. To accomplish this aim, we used a sample of innovative firms from the region of Valencia (Spain). The chosen region has specific structural characteristics, which are discussed later. Although the sampled firms compete with one another, they also collaborate with each other and with in…
The relationship between non-audit fees and audit quality: dealing with the endogeneity issue
2015
Purpose – The purpose of this paper is to explore whether the provision of non-audit services (NAS) by public accounting firms undermines audit quality. The study addresses this question by testing for an association between the provision of consulting services and auditor independence in listed companies. Design/methodology/approach – The authors study if the magnitude of non-audit fees explains variations in earnings management by looking at the joint determination of non-audit fees, audit fees, and abnormal accruals using the SURE-regression estimation method. Findings – Evidence from tested models suggests that audit services quality is uncompromised by the provision of NAS. In other w…
Innovation through implementation of a quality improvement method : A finnish public-sector case
2019
Purpose The purpose of this paper is to analyse the effectiveness of a quality improvement method in driving innovation in the public sector. The study expands on the concept of innovation and analyses the types and usefulness of the innovations observed. Design/methodology/approach The study utilizes an action research approach. The aim of the quality improvement method introduced is to generate innovations enhancing efficiency. An interventionist research method is required to produce the findings. Data collection methods include a preliminary question sheet, interview, workshops, observation and the examination of other material concerning the case organization. Findings The study suppo…
Une stratégie de test de la racine unitaire
1991
This paper compares three approaches of the unit root testing strategy issue : i.e. the DICKEY, BELL and MILLER (1986) approach, elaborated for prevision purposes, which advocates the estimation of a model without trend at the outset, in opposition to the PERRON (1988) and HENIN and JOBERT (1990) testing strategies. The latter is undoubtedly operational in empirical works but it doesn’t encompass joint tests explicitly. We then suggest an unifiedgeneral framework embracing the last two appoaches and giving a practical scheme which is as complete and operational as possible. The behaviour of these strategies is assesed in an empirical study of the seasonaly adjusted real GDP in France and an…