Search results for "Stress."
showing 10 items of 5934 documents
Ecophysiological and molecular processes involved in water stress memory in pea: from gene expression regulation to plant hydromineral nutrition
2022
Climate change induces increasingly frequent periods of water deficits during the crop cycle. These periods of water stress negatively impact the plant, notably by limiting the availability of resources (water, mineral elements) and by limiting carbon fixation by the plant. In this context, several studies highlighted the beneficial effect of “priming” of a first stress on the response to a second stress by the induction of a transcriptional memory. This memory depends on epigenetic modifications implemented during the first stress. These modifications can regulate the expression of genes known as “memory genes” which have been characterized in the aerial parts of Arabidospsis and maize. Ho…
Cognitive Performance and Psychological Distress in Breast Cancer Patients at Disease Onset
2019
ObjectiveMany cancer patients complain about cognitive dysfunction. While cognitive deficits have been attributed to the side effects of chemotherapy, there is evidence for impairment at disease onset, prior to cancer-directed therapy. Further debated issues concern the relationship between self-reported complaints and objective test performance and the role of psychological distress.MethodWe assessed performance on neuropsychological tests of attention and memory and obtained estimates of subjective distress and quality of life in 27 breast cancer patients and 20 healthy controls. Testing in patients took place shortly after the initial diagnosis, but prior to subsequent therapy.ResultsWhi…
Perheenjäsenten kokemukset työ- ja perhe-elämästä - päivittäiset stressikokemukset ja niiden yhteys mielialaan
2005
A Group Intervention to Promote Resilience in Nursing Professionals: A Randomised Controlled Trial
2022
In this study, a new group intervention program to foster resilience in nursing professionals was tested for efficacy. In total, 72 nurses were recruited and randomised to either an intervention condition or to a wait list control condition. The study had a pre-test, post-test, follow-up design. The eight-week program targeted six resilience factors: cognitive flexibility, coping, self-efficacy, self-esteem, self-care, and mindfulness. Compared to the control group, the intervention group reported a significant improvement in the primary outcome mental health (measured with the General Health Questionnaire) from pre-test (M = 20.79; SD = 9.85) to post-test (M = 15.81; SD = 7.13) with an est…
Psychosocial Safety Climate: A New Work Stress Theory and Implications for Method
2019
This book responds to a public health priority (Whiteford et al., 2013) and a call from the WHO (2016), ILO (2016) and OECD (2012) to prevent and manage mental ill-health and promote health and well-being by drawing attention to the connection between work and mental health. By demonstrating a link between work factors and mental health-related issues, this book will provide public policy makers with evidence needed to shift policy attention to create mentally healthy workplaces and move investment of health, compensation, and insurance funding into proactive prevention strategies rather than costly treatments, medications, therapy, and hospitalisation. Ensuring workplaces globally have the…
CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions
2021
BackgroundWithin the bone marrow (BM), mature T cells are maintained under homeostatic conditions to facilitate proper hematopoietic development. This homeostasis depends upon a peculiar elevated frequency of regulatory T cells (Tregs) and immune regulatory activities from BM-mesenchymal stem cells (BM-MSCs). In response to BM transplantation (BMT), the conditioning regimen exposes the BM to a dramatic induction of inflammatory cytokines and causes an unbalanced T-effector (Teff) and Treg ratio. This imbalance negatively impacts hematopoiesis, particularly in regard to B-cell lymphopoiesis that requires an intact cross-talk between BM-MSCs and Tregs. The mechanisms underlying the ability of…
Postnatal predator exposure reduces fear and anxiety behaviors in adult mice
2010
Poster; Predator cues are very efficient to induce fear in rodents but most studies use adult subjects and not pups. Nevertheless, a perinatal stress can have a significant effect on behavior and on physiology at adulthood. An early stress (foot shock, restraint, mother separation) is able to modulate behaviors later and the aim of this study was to examine if the synthetic predator odor 2,3,5-trimethylthiazoline (TMT) presented to neonates modifies fear and anxiety-related behaviors in adult female mice.
Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases
2021
Aging is a physiological process defined by decreased cellular and tissue functions. Reduced capacity of protein degradation is one of the important hallmarks of aging that may lead to misfolded protein accumulation and progressive loss of function in organ systems. Recognition of unfolded/misfolded protein aggregates via endoplasmic reticulum (ER) stress sensors activates an adaptive mechanism, the unfolded protein response (UPR). The initial step of UPR is defined by chaperone enhancement, ribosomal translation suppression, and misfolded protein degradation, while prolonged ER stress triggers apoptosis. MicroRNAs (miRNAs) are non-coding RNAs affecting various signaling pathways through de…
FUNCTIONAL GENOMIC APPROACHES TO ELUCIDATE BIOTIC AND ABIOTIC STRESS RESPONSES IN PLANTS
Miega traucējumi kā operāciju māsas darba kvalitātes ietekmējošais faktors
2020
Bakalaura darba tēma „Miega traucējumi kā operāciju māsas darba kvalitātes ietekmējošais faktors”. Tēmas aktualitāti nosaka praktizējošu operāciju māsu trūkums veselības aprūpē. Ar šo problēmu saskaras ne tikai operāciju māsas, bet visas veselības aprūpes nozare. Operāciju māsām jāsastopas ar augstu darba slodzi, samazinātu medicīnas personālu un stresu, kas ietekmē uz miega kvalitāti. Sakarā ar paaugstinātu darba slodzi pieaug spriedze, līdz ar to miega kvalitāte pasliktinās un līdz ar to samazinās darba ātrums, koncentrācijas spēja kura dēļ operācijas māsa var pieļaust kļūdu darbā. Pētījuma jautājums – Kā miega traucējumi ietekmē operācijas māsu darbu? Veicot pētījuma analīzi, darba autor…