Search results for "Strongyloides"
showing 7 items of 17 documents
Strongyloides mascomaisp. n. (Strongyloididae) un nouveau Nématode parasite deRana pereziSeoane, 1885 (Amphibia : Ranidae) de l’est de l’Espagne
1989
SUMMARY. Description and differentiation of the parasite stage of Strongyloides mascomai sp. n. (Nematoda: Strongyloididae), an cloacal parasite of Rana perezi Seoane, 1885 in the east of Iberian Peninsula (Spain). The new species is charac-terized for its large length of the oesophagus, the morphology of its stoma and the moderate spiralation of the ovaries of the female parasite.
Proteomic analysis of Strongyloides stercoralis L3 larvae
2010
SUMMARYStrongyloidiasis can be perpetuated by autoinfection with the filariform larvae L3, causing asymptomatic chronic infections and creating a population of carriers, affecting not only developing countries. So far, very little is known about the proteins that interact with the human host, and few proteins from the infective Strongyloides stercoralis L3 have been characterized. Here, we report results obtained from a proteomic analysis of the proteins from S. stercoralis L3 larvae obtained from patients. Since the genome of S. stercoralis is not yet available, we used proteomic analysis to identify 26 different proteins, 13 of them released by short digestion with trypsin, which could re…
Identificación y caracterización de proteínas de Strongyloides stercoralis de utilidad para el diagnóstico y control de la enfermedad mediante técnic…
2016
El nematodo Strongyloides stercoralis es el principal causante de la estrongiloidiasis humana. Debido a la capacidad del parásito de perpetuar un ciclo autoinfectivo la infección puede prolongarse durante años en el hospedador, dando lugar a una enfermedad crónica en personas inmunocompetentes, mientras que en condiciones de inmunosupresión puede desembocar en cuadros clínicos graves con elevadas tasas de mortalidad. La región de La Safor valenciana ha sido considerada foco endémico de este parásito desde hace más de un siglo, habiéndose diagnosticado cientos de casos desde entonces, suponiendo un problema sanitario en la región. La presente Tesis contribuye a la mejora en el conocimiento p…
The transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected disease.
2012
Background: Strongyloidiasis is one of the most neglected diseases distributed worldwide with endemic areas in developed countries, where chronic infections are life threatening. Despite its impact, very little is known about the molecular biology of the parasite involved and its interplay with its hosts. Next generation sequencing technologies now provide unique opportunities to rapidly address these questions. Principal Findings: Here we present the first transcriptome of the third larval stage of S. stercoralis using 454 sequencing coupled with semi-automated bioinformatic analyses. 253,266 raw sequence reads were assembled into 11,250 contiguous sequences, most of which were novel. 8037…
Hiperinfección por Strongyloides stercoralis
2010
El Strongyloides stercoralis (Ss) es un nematodo endémico en países de clima tropical y subtropical, y en España se han descrito casos, sobre todo en la costa mediterránea. La infección por Ss suele ser asintomática o manifestarse por síntomas predominantemente digestivos, y en los casos de hiperinfestación produce una estrongiloidiasis diseminada con sobreinfecciones bacterianas sistémicas que provocan una disfunción multiorgánica con resultado letal. Los factores de riesgo más importantes para que una infección en principio intestinal y en muchas ocasiones asintomática adquiera características de gravedad son la inmunosupresión y la utilización de corticoides, por su capacidad de alterar …
931 Intestinal Parasites in Internationally Adopted Children in Belgium
2012
Background and Aims 314 internationally adopted children were seen between 01/01/2008 and 31/03/2012 at the Institute of Tropical Medicine in Antwerp (Belgium). We describe the prevalence of pathogenic intestinal parasites in this population. Methods Retrospective analysis of patient records. Feces samples were obtained in 307/314 children. In addition, serology for Strongyloides and Schistosoma was performed. Results Pathogenic parasites were found in 55.7% (53% in children 0–5 years, 72.1% > 5years). When counting any parasites, 65.9% of children were found positive (61.4% for 0–5 years, 93% for >5 years). 37.5% of children with positive samples had ≥ 3 parasites. Analysis by age in child…
Strongyloidiasis with Emphasis on Human Infections and Its Different Clinical Forms
2015
Strongyloidiasis (caused by Strongyloides stercoralis, and to a lesser extent by Strongyloides fuelleborni) is one of the most neglected tropical diseases with endemic areas and affecting more than 100 million people worldwide. Chronic infections in endemic areas can be maintained for decades through the autoinfective cycle with the L3 filariform larvae. In these endemic areas, misdiagnosis, inadequate treatment and the facilitation of the hyperinfection syndrome by immunosuppression are frequent and contribute to a high mortality rate. Despite the serious health impact of strongyloidiasis, it is a neglected disease and very little is known about this parasite and the disease when compared …