Search results for "Study"
showing 10 items of 15483 documents
Associations of Children’s Close Reading Distance and Time Spent Indoors with Myopia, Based on Parental Questionnaire
2022
Purpose: To study the association of parents’ reports about their children’s near work and outdoor habits with myopia in their children. Methods: Data from a questionnaire study conducted in 1983 among Finnish schoolchildren were reanalyzed. Vision screening had been performed for all the schoolchildren (n = 4961) in the 1st, 5th, and 8th grades (7-, 11-, and 15-year-olds) in an area of Central Finland. The questionnaire, including information about myopia, was returned by 4305 (86.7%) participants. Items concerned parents’ estimates of their child’s habitual reading distance, time spent indoors as compared with age peers, daily near work, outdoors time, and parents&…
Single-cell analysis of population context advances RNAi screening at multiple levels
2012
Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironment, in image‐based RNAi screens. We developed a comprehensive computational approach that employs Bayesian and multivariate methods at the single‐cell level. We applied these methods to 45 RNA interference screens of various sizes, including 7 druggable genome and 2 genome‐wide screens, analysing 17 different mammalian virus infections and four related cell physiological processes. Analysing cell‐based screens at this depth reveals widespread RNAi‐induce…
Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy
2015
Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of the present study was to investigate the usefulness of the preoperative mGPS as predictor of recurrence-free (RFS), overall (OS), and cancer-specific (CSS) survivals in a large cohort of urothelial bladder cancer (UBC) patients.A total of 1037 patients with UBC were included in this study with a median follow-up of 22 months (range 3-60 months). An mGPS = 0 was observed in 646 patients (62.3%), mGPS = 1 in 297 pa…
Irtisanomisilmoituksen vaikutus yhtiön osakekurssiin : event study -analyysi suomalaisten pörssiyhtiöiden irtisanomisista 2000-2004
2005
Response-To-Intervention in Finland and the United States: Mathematics Learning Support as an Example
2018
Response to Intervention (RTI) was accepted in the early 2000s as a new framework for identifying learning difficulties (LD) in the U.S. In Finland, a similar multi-tiered framework has existed since 2010. In the present study, these frameworks are presented from the viewpoint of the role of assessment and instruction as expressed in documents that describe the frameworks, as it seems that these two components of RTI are the most disparate between the U.S. and Finland. We present a suggestion for the Finnish framework as an example of support in mathematics learning that incorporates principles of RTI (such as systematized assessment and instruction, cyclic support, and modifiable instructi…
Motivation to learn English : a case study of a 7th grade class
2017
Motivaatiota ja sen vaikutusta kielen oppimiseen on tutkittu laajalti. Tämän tutkimuksen tarkoituksena on selvittää 7. luokkalaisten opiskelumotivaatiota, kun he ovat aloittaneet yläkoulun uudessa koulussa, uudessa luokassa ja uuden opettajan kanssa. Keskeisenä kysymyksenä on: Mikä saa 7. luokkalaisen ymmärtämään motivaation merkityksen englannin kielen opiskelussa? Tämä tutkimus keskittyy oppilaiden narratiivisiin kirjoitelmiin, jossa he tuovat esiin omia näkökulmiaan ja ajatuksiaan oppimiseen motivoivista tekijöistä sekä oppimisen motivaatiota heikentävistä tekijöistä. Tutkimus toteutettiin narratiivisten kirjoitelmien avulla tapaustutkimuksena. Tutkimukseen osallistui oppilaita vain yhde…
Infantilas rīšanas paradumi un citas orofaciālā kompleksa atradnes pirmsskolas vecuma bērniem Latvijā
2019
Ievads: Pētījuma mērķis bija izpētīt saikni starp infantilas rīšanas paradumiem ar citām orofaciālā kompleksa atradnēm pirmsskolas vecuma bērniem Latvijā. Paralēli tam mēs pētījām arī oklūziju. Metodes: Šajā šķērsgriezuma pētījumā piedalījās 141 pirmsskolas vecuma bērnu no 4 līdz 7 gadiem un viņu mātes. Orofaciālā kompleksa izmeklēšanu veica divi ortodonti, kurā tika novērtēta orofaciālā kompleksa miofunkcionālā situācija, oklūzija un bērnu runas defekti. Mātēm tika sniegtas anketas, lai iegūtu informāciju par bērnu veselības stāvokli un citiem identifikācijas datiem. Tika veikta aprakstoša statistika visiem pētījuma mainīgajiem lielumiem un vienvirziena analīze starp infantilo rīšanu un vi…
Predictors of changing patterns of adherence to containment measures during the early stage of COVID-19 pandemic: an international longitudinal study
2023
Abstract Background Identifying common factors that affect public adherence to COVID-19 containment measures can directly inform the development of official public health communication strategies. The present international longitudinal study aimed to examine whether prosociality, together with other theoretically derived motivating factors (self-efficacy, perceived susceptibility and severity of COVID-19, perceived social support) predict the change in adherence to COVID-19 containment strategies. Method In wave 1 of data collection, adults from eight geographical regions completed online surveys beginning in April 2020, and wave 2 began in June and ended in September 2020. Hypothesized pre…
The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols i…
2020
Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line treatments for tics are antipsychotics and tic-specific behavioral therapies. However, due to a lack of trained therapists and adverse events of antipsychotic medication many patients seek alternative treatment options including cannabis. Based on the favorable results obtained from case studies on different cannabis-based medicines as well as two small randomized controlled trials using delta-9-tetrahydrocannabinol (THC), we hypothesize that the cannabis extract nabiximols can be regarded as a promising new and safe treatment strategy in TS.Objective: To …
The Need to Approach the Management of the Tourist Destination by the Central and Local Public Authorities in Romania
2017
Abstract In the medium and long term, priorities in the development of tourism aim to develop a complex tourist offer, making the most of the natural and anthropogenic resources existing in connection with the preservation of the environment and the heritage. On the long run, it will contribute to raising the living standards of the population, especially social categories with lower chances of reintegration into the labour market (people made redundant in industry, elderly people etc.). Implementation of the strategy at regional level must be achieved through an active partnership between Romanian public authorities, economic agents and private investors, with the involvement of the federa…