Search results for "Sublingual immunotherapy"

showing 6 items of 16 documents

Safety of sublingual immunotherapy started during the pollen season

2009

Sublingual immunotherapy (SLIT) is safer than subcutaneous immunotherapy (SCIT) and this has lead to the reconsideration of the use of ultra-rush schedules for SLIT. The aim of this study was to assess the safety of ultra-rush SLIT in pollen-allergic children according to different timing of administration in relation to the pollen season.In total, 34 children with pollen-induced rhinitis and 36 with pollen-induced asthma and rhinitis, were enrolled and assigned to three study groups: group 1 (n = 17 patients): conventional pre-seasonal-SLIT treatment; group 2 (n = 23 patients), seasonal SLIT ended before the pollen seasonal peak; group 3 (n = 30 patients), SLIT began after the pollen seaso…

Study groupsmedicine.medical_specialtyPediatricsAdolescentAdministration SublingualPollen Allergymedicine.disease_causePollenotorhinolaryngologic diseasesmedicineSubcutaneous immunotherapyHumansRhinitis Allergic Seasonal; Humans; Allergens; Asthma; Desensitization Immunologic; Child; Adolescent; Administration Sublingual; Pollen; Child PreschoolSublingual immunotherapyChildAsthmaPollen seasonbusiness.industryAllergenRhinitis Allergic Seasonalfood and beveragesGeneral MedicineAllergensmedicine.diseaseSlitAsthmaeye diseasesSurgerySLIT Ultra-RUSHDesensitization ImmunologicChild PreschoolPollensense organsbusinessHuman
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Efficacy but not effectiveness of sublingual immunotherapy for grass pollen allergy: Time to avoid waste in health-care expenditure

2015

Sublingual immunotherapymedicine.medical_specialtybusiness.industryAllergenTreatment outcomeGrass pollenAlternative medicineWelfareRhinitis Allergic SeasonalGrass pollen allergyEconomic burdenAntigens PlantHealth Care CostTreatment OutcomeGrass pollenImmunologyHealth careInternal MedicinemedicineMeta-analysiSublingual immunotherapyIntensive care medicinebusinessDecision-makingHumanEuropean Journal of Internal Medicine
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Efficacy of sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: A systematic review and meta-analysis

2010

Background The benefit of sublingual immunotherapy (SLIT) with grass allergens for seasonal allergic rhinitis has been extensively studied, but data on efficacy are still equivocal. Objective To assess the effectiveness of SLIT with grass allergens in the reduction of symptoms and medication in patients with seasonal allergic rhinitis to grass pollen. Methods Computerized bibliographic searches of MEDLINE (1995-2010) were supplemented by hand searches of reference lists. Studies were included if they were double-blind randomized controlled trials (RCTs) comparing SLIT to placebo and if they included patients with history of allergy to grass pollen treated with natural grass pollen extracts.…

medicine.medical_specialtyAllergyMEDLINEImmunologyAdministration SublingualPlaceboPoaceaelaw.inventionSublingual administrationRandomized controlled triallawInternal medicineotorhinolaryngologic diseasesImmunology and AllergyMedicineHumansSublingual immunotherapy rhinitis grass meta-analysisAdverse effectRandomized Controlled Trials as Topicbusiness.industryfood and beveragesRhinitis Allergic Seasonalmedicine.diseaseSlitTreatment OutcomeStrictly standardized mean differenceMeta-analysisImmunologyPollenImmunotherapybusiness
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Efficacy of Grass Pollen Allergen Sublingual Immunotherapy Tablets for Seasonal Allergic Rhinoconjunctivitis: A Systematic Review and Meta-analysis.

2015

IMPORTANCE: Randomized clinical trials (RCTs) and meta-analyses of sublingual immunotherapy (SLIT) for the treatment of seasonal allergic rhinoconjunctivitis (SARC) have shown a modest clinical benefit compared with placebo. Furthermore, indirect comparison by meta-analyses showed that subcutaneous immunotherapy is more effective than SLIT. Despite these data, SLIT has become the most prescribed treatment of SARC in Europe in recent years, and it was approved by the US Food and Drug Administration for the treatment of SARC to grass pollen in the United States on April 1, 2014. OBJECTIVE: To assess the efficacy and safety of the grass pollen sublingual tablets licensed as drugs in the treatm…

medicine.medical_specialtyMEDLINECochrane LibraryPlaceboPlant Extractlaw.inventionRandomized controlled triallawInternal medicineInternal MedicinemedicineClinical endpointmedia_common.cataloged_instanceHumansEuropean unionAdverse effectmedia_commonConjunctivitis AllergicSublingual Immunotherapybusiness.industryPlant ExtractsAllergenMedicine (all)Rhinitis Allergic SeasonalAllergensAntigens PlantMeta-analysisImmunologybusinessHumanJAMA internal medicine
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Adherence issues related to sublingual immunotherapy as perceived by allergists.

2010

Silvia Scurati1, Franco Frati1, Gianni Passalacqua2, Paola Puccinelli1, Cecile Hilaire1, Cristoforo Incorvaia3, Italian Study Group on SLIT Compliance 1Scientific and Medical Department, Stallergenes, Milan, Italy; 2Allergy and Respiratory Diseases, Department of Internal Medicine, Genoa; 3Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, ItalyObjectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered…

medicine.medical_specialtyPathologygenetic structuresefficacyAlternative medicineMedicine (miscellaneous)Adherence Cost Efficacy Side effects Sublingual immunotherapySettore MED/10 - Malattie Dell'Apparato Respiratoriosublingual immunotherapyALLERGENcostmedicineSubcutaneous immunotherapySublingual immunotherapyadherenceClinical efficacyIntensive care medicinePharmacology Toxicology and Pharmaceutics (miscellaneous)sublingual immunoterapyOriginal ResearchAsthmaAEROALLERGENSadherence; sublingual immunotherapy; efficacy; cost; side effectsbusiness.industryHealth Policymedicine.diseaseSliteye diseasesClinical trialside effectsPatient Preference and Adherenceadherence; sublingual immunoterapy; efficacy; cost; side effects.immunotherapysense organsAllergistsADHERENCE TO TREATMENTbusinessSocial Sciences (miscellaneous)
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Efficacy of subcutaneous and sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: a meta-analysis–based comparison

2012

Background: Subcutaneous (SCIT) and sublingual (SLIT) immunotherapy are the 2 most prescribed routes for administering allergen-specific immunotherapy. They were shown to be effective in control of symptoms and in reducing rescue medication use in patients with allergic diseases, but their effectiveness has to be balanced against side effects. In recent years, SLIT has been increasingly prescribed, instead of SCIT, because of improved safety and easy administration. Objective: We assessed which route is the most effective in the treatment of patients with seasonal allergic rhinitis to grass pollen. Methods: An indirect meta-analysis–based comparison between SCIT and SLIT was performed. Trea…

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentImmunologySublingual immunotherapy subcutaneous immunotherapy allergic rhinitis grass meta-analysisPlaceboSlitlaw.inventionSettore MED/01 - Statistica MedicaRandomized controlled trialStrictly standardized mean differencelawMeta-analysisInternal medicineImmunologymedicineImmunology and AllergySublingual immunotherapybusinessAdverse effectDesensitization (medicine)
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