Search results for "Substance abuse"

showing 10 items of 271 documents

Genetic and environmental contributions to the inverse association between specific autistic traits and experience seeking in adults

2015

Autistic traits are characterized by social and communication problems, restricted, repetitive and stereotyped patterns of behavior, interests and activities. The relation between autistic traits and personality characteristics is largely unknown. This study focused on the relation between five specific autistic traits measured with the abridged version of the Autism Spectrum Quotient ("social problems," "preference for routine," "attentional switching difficulties," "imagination impairments," "fascination for numbers and patterns") and Experience Seeking (ES) in a general population sample of adults, and subsequently investigated the genetic and environmental etiology between these traits.…

AdultMaleAutism-spectrum quotientmedicine.medical_specialtyInverse Associationmedia_common.quotation_subjectTwinsEnvironmentDevelopmental psychology03 medical and health sciencesCellular and Molecular NeuroscienceRisk-Taking0302 clinical medicinemedicineHumansSensation seekingPersonalityAttention0501 psychology and cognitive sciencesAutistic DisorderAssociation (psychology)Genetics (clinical)Netherlandsmedia_commonGeneticsSiblings05 social sciencesmedicine.diseasePreferenceSubstance abusePsychiatry and Mental healthAutistic traitsEtiologyMedical geneticsAutismFemalePsychology030217 neurology & neurosurgeryPersonality050104 developmental & child psychologyAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics
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Lay understanding of the causes of binge drinking in the United Kingdom and Australia: a network diagram approach

2017

​Binge drinking is associated with deleterious health, social and economic outcomes. This study explored the lay understanding of the causes of binge drinking in members of the general public in the United Kingdom and Australia. Participants in the United Kingdom (N = 133) and Australia (N = 102) completed a network diagram exercise requiring them to draw causal paths and provide path strength ratings between 12 candidate factors (24-h opening, age, alcohol advertizing, alcohol availability, boredom, drinking culture, income, low cost, parental influence, peer pressure, stress and supermarket discounts) and binge drinking. Results indicated good consistency in paths across samples, although…

AdultMaleC850 Cognitive Psychologymedicine.medical_specialtyC840 Clinical Psychologypeer pressure030508 substance abuseBinge drinkingPublic opinionboredomPeer GroupEducationParental influence03 medical and health sciencesC841 Health PsychologyC810 Applied Psychology0302 clinical medicinemedicineHumans030212 general & internal medicinePeer pressurePsychiatryPath analysis (statistics)Causal modelModels Statisticalbusiness.industryAustraliaPublic Health Environmental and Occupational HealthSocial Supportta3141BoredomDrinking cultureAwarenessC800 PsychologyUnited Kingdombinge drinkingFemaleethanolmedicine.symptom0305 other medical sciencebusinessPsychologyHealth Education Research
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The relationship of personality traits to substance abuse in patients with bipolar disorder

2007

AbstractPurposeThe aim of this study is to determine if personality traits contribute to the likelihood of substance abuse in Bipolar Disorder (BD).Subjects/materials and methodsFifty-nine patients meeting DSM-IV criteria for BD: 20 without any history of Substance Related Disorder (SRD), 21 with a lifetime history of SRD but without current SRD, and 18 with current SRD. Patients filled out the TCI, the differences were analyzed by ANOVA and the likelihood was obtained by Multinomial Logistic Regression.ResultsOnly Novelty Seeking (NS) is statistically different between the groups. Patients with BD with current SRD have higher rates in NS than those with past SRD, and those without a histor…

AdultMaleCharactermedicine.medical_specialtyBipolar DisorderPersonality InventoryPsychometricsPsychometricsSubstance-Related Disordersmedia_common.quotation_subjectStatistics as TopicComorbidity03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineHumansPersonalityBipolar disorderTemperamentPsychiatrymedia_commonPsychiatric Status Rating ScalesNovelty seekingReproducibility of ResultsSubstance-related disorderMiddle Agedmedicine.diseaseComorbidity030227 psychiatrySubstance abusePsychiatry and Mental healthExploratory BehaviorFemaleTemperamentPsychology030217 neurology & neurosurgeryEuropean Psychiatry
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Childhood Victimization by Adults and Peers and Health-Risk Behaviors in Adulthood

2019

AbstractVictimization experienced in childhood has been linked with health-risk behaviors (HRBs) in adulthood. The purpose of this cross-sectional survey was to provide data regarding the HRBs using the ISPCAN Child Abuse Screening Tool Retrospective version (ICAST-R), Spanish version. This aimed to broaden existing knowledge by assessing both being victimized by adults and by peers in a Spanish general population of 348, aged 18–35. Age and timing of the reported victimization were also considered. Victimization: physical, psychological, sexual abuse by adults and/or peers showed a prevalence of 44.54%. Of these, 41.29% reported abuse by both. Children victimized by adults, regardless of t…

AdultMaleChild abuseLinguistics and LanguageAdolescentSubstance-Related DisorderseducationPopulationPoison controlSuicide AttemptedSuicide preventionPeer GroupLanguage and LinguisticsYoung Adult03 medical and health sciences0302 clinical medicineInjury preventionmedicineHumans0501 psychology and cognitive sciencesChild Abuse030212 general & internal medicineChildeducationCrime Victimshealth care economics and organizationsGeneral Psychologyeducation.field_of_studyAdult Survivors of Child AbuseMental Disorders05 social sciencesBullyingsocial sciencesmedicine.diseaseSubstance abuseCross-Sectional StudiesAdult Survivors of Child Adverse EventsSexual abuseChild PreschoolPeer victimizationFemalePsychology050104 developmental & child psychologyClinical psychologyThe Spanish Journal of Psychology
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Noninvasive double confirmation of cocaine abuse.

2013

A double confirmation procedure, based on the combined application of Ion Mobility Spectrometry (IMS) and Infrared Spectroscopy (IR), has been developed for the noninvasive unambiguous identification of cocaine consume. The use of nasal mucus as a biological specimen for cocaine abuse confirmation has been proposed as an alternative to the use of blood and urine due to its noninvasive character and the presence of the parent compound instead of its metabolites. Sampling conditions, interferences caused by cutting agents and other substances, and limits of identification (LOI) and confirmation (LOC) have been deeply evaluated. The procedure combines the high sensitivity of the IMS to identif…

AdultMaleChromatographyChemistryIon-mobility spectrometryHigh selectivityAnalytical chemistryAnalytical ChemistrySubstance Abuse DetectionBiological specimenCocaine-Related DisordersMucusNasal MucosaCocaineNasal mucusSpectroscopy Fourier Transform InfraredHumansFemaleCocaine abuseAnalytical chemistry
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Development and validation of a reliable method for studying the distribution pattern for opiates metabolites in brain

2012

Abstract Brain distribution pattern of “street” heroin metabolites (morphine and codeine) was investigated in two fatalities due to “acute narcotism”. A suitable sample pretreatment prior to solid-phase-extraction was developed to achieve a good recovery of the analytes and to eliminate the interfering species. After derivatization with MSTFA, samples were analyzed by GC/MS. Specificity, accuracy, precision and linearity of the method were evaluated; LOD and LOQ were, respectively, 10 ng/25 ng for morphine and 5 ng/10 ng for codeine. This method was applied to the analysis of six brain areas (hippocampus, frontal lobe, occipital lobe, nuclei, bulb and pons) coming from two cases of heroin-r…

AdultMaleClinical BiochemistryAnalytical chemistryPharmaceutical ScienceHippocampusGas Chromatography-Mass SpectrometryAnalytical ChemistryHeroinchemistry.chemical_compoundSettore MED/43 - Medicina LegaleLimit of DetectionDrug DiscoverymedicineHumansTissue DistributionDerivatizationSpectroscopyHeroin; Morphine; Codeine; Post-mortem brain specimenChromatographyMolecular StructureMorphineCodeineHeroin DependenceIllicit DrugsCodeineBrainReproducibility of ResultsPonsHeroinSubstance Abuse DetectionchemistryFrontal lobeMorphinePost-mortem brain specimenDrug OverdoseOccipital lobemedicine.drug
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Infectious diseases among foreign prisoners: results of a hospital-based management model in Palermo.

2017

Foreign prisoners have a high vulnerability in terms of morbidity and access to care in overcrowded Italian prisons. This paper presents and comments on the management model of infectious diseases in foreign prisoners at our outpatient clinic, in order to describe a model of management for these conditions. Overall, 133 subjects (mean age 35.5 years) from 29 countries were followed for a period of 15 years. The most commonly represented area of origin (54.1%) was the Maghreb region. HCV infection (40.6%), HIV (22.5%), HBV (9.8%) and co-infection (15%, HIV/HCV or HIV/HBV) were observed. Ten subjects had tuberculosis, and only 30% of them were compliant with the treatment. Only 46.3% of HCV m…

AdultMaleCoinfectionPrisonersHIV InfectionsHepatitis BCommunicable DiseasesHepatitis CHealth Services AccessibilityItalyRisk FactorsPrisonsPrevalenceInfectious diseasesHumansFemaleSubstance Abuse IntravenousSicilyTuberculosis PulmonaryRetrospective StudiesLe infezioni in medicina
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Improved drug-use patterns at 6 months post-discharge from inpatient substance use disorder treatment: Results from compulsorily and voluntarily admi…

2016

Background Treatment services to patients with substance use disorders (SUDs), including those mandated to treatment, needs to be evaluated and evidence based. The Norwegian Municipal Health Care Act calls for mandated treatment for persons with “severe and life-threatening substance use disorder” if these individuals are not otherwise willing to be voluntarily treated and consequently risk their lives over drug use. This study aims to examine substance use–related outcomes at 6 months following inpatient treatment and to analyse factors associated with improved outcomes and abstinence. Method This prospective study followed 202 hospitalized patients with SUD who were admitted voluntarily (…

AdultMaleDrugmedicine.medical_specialtyEvidence-based practiceSubstance-Related DisordersCompulsory treatmentmedia_common.quotation_subject030508 substance abuseMandatory ProgramsSubstance use disorderMedication Adherence03 medical and health sciences0302 clinical medicineInternal medicineHealth caremedicineHumansProspective Studies030212 general & internal medicinePsychiatryAmphetamineProspective cohort studymedia_commonInpatientsNorwaybusiness.industryPublic healthHealth PolicyAbstinencemedicine.diseasePatient DischargeHospitalizationSubstance abuseTreatment OutcomeRegression AnalysisFemale0305 other medical sciencebusinessResearch Articlemedicine.drug
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Prevalence of and potential influencing factors for alcohol dependence in Europe.

2014

Alcohol use disorders (AUDs), and alcohol dependence (AD) in particular, are prevalent and associated with a large burden of disability and mortality. The aim of this study was to estimate prevalence of AD in the European Union (EU), Iceland, Norway, and Switzerland for the year 2010, and to investigate potential influencing factors. The 1-year prevalence of AD in the EU was estimated at 3.4% among people 18-64 years of age in Europe (women 1.7%, men 5.2%), resulting in close to 11 million affected people. Taking into account all people of all ages, AD, abuse and harmful use resulted in an estimate of 23 million affected people. Prevalence of AD varied widely between European countries, and…

AdultMaleHealth (social science)AdolescentGross Domestic ProductMedicine (miscellaneous)Poison controlSuicide preventionOccupational safety and healthYoung AdultSex FactorsLiver Cirrhosis AlcoholicEnvironmental healthNeoplasmsInjury preventionPrevalenceSocial NormsMedicinemedia_common.cataloged_instanceHumansEuropean unionmedia_commonbusiness.industryAlcohol dependenceHuman factors and ergonomicsMiddle Agedmedicine.diseaseSubstance abuseEuropePsychiatry and Mental healthAlcoholismWounds and InjuriesFemaleMedical emergencybusinessEuropean addiction research
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Reliability and validity of the form 90 interview.

2004

<i>Objective:</i> Alcohol consumption is a central variable in substance abuse research and treatment. The study reports the psychometric characteristics of the German version of the Form 90 interview for the assessment of recent alcohol consumption. <i>Method:</i> Reliability was evaluated in a test-retest study (7 days) with 30 consecutively admitted psychiatric inpatients with alcohol dependence. Validity of Form 90 was assessed with a second sample of 60 alcohol-dependent inpatients. <i>Results:</i> Form 90 demonstrated good to excellent retest reliability for the central variables of alcohol consumption. Retest reliability Pearson correlation coeffic…

AdultMaleHealth (social science)Alcohol DrinkingPsychometricsIntraclass correlationSubstance-Related DisordersTemperanceStatistics as TopicMedicine (miscellaneous)AlcoholComorbidityMedical RecordsAlcohol Withdrawal Deliriumchemistry.chemical_compoundsymbols.namesakeGermanyInterview PsychologicalmedicineHumansReliability (statistics)Mental DisordersAlcohol dependenceReproducibility of ResultsMiddle Agedmedicine.diseaseConfidence intervalPearson product-moment correlation coefficientSubstance abuseHospitalizationPsychiatry and Mental healthAlcoholismchemistryStructured interviewsymbolsPatient ComplianceFemalePsychologyClinical psychologyFollow-Up StudiesEuropean addiction research
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