Search results for "Substance use"
showing 10 items of 79 documents
T110. FIRST EPISODE PSYCHOTIC PATIENTS WITH A HISTORY OF FREQUENT CANNABIS USE EXPRESS MORE POSITIVE SYMPTOMS AT ILLNESS ONSET THAN THOSE WHO NEVER U…
2018
Abstract Background Robust evidence has demonstrated that cannabis use increases the risk to develop psychotic disorders. However, a limited number of studies have investigated if and how cannabis use influences psychopathology profiles at first episode psychosis (FEP). Based on the evidence that dopamine dysfunction contributes to explain positive symptoms in psychosis, and that the main cannabis’ psychoactive component, Δ9-Tetrahydrocannabinol (THC), modulates the dopamine system, we hypothesise that: 1) positive symptoms at FEP are more common among psychotic patients who used cannabis compared with never users; 2) this association is a dose-response relationship. Methods We analyzed a s…
Factores asociados al consumo de drogas en una muestra de militares españoles desplegados en “Bosnia-Herzegovina”
2017
The use of both legal and illegal drugs has rarely been investigated among the Spanish military population involved in multinational military operations. The aim of the current study was to examine the consumption of drugs by Spanish military personnel in Bosnia-Herzegovina, and the variables associated with such substance use. A total of 605 military personnel participated in the cross-sectional study. The participants’ mean age was 25.9 years (SD = 5.9), and 93.9% of the sample was male. The majority of the participants were enlisted personnel (83.5%). The most widely used drugs were tobacco (54.2%), and alcohol (39.9%). With respect to illegal drugs, the results showed that the drug with…
International perspectives on social media use among adolescents: Implications for mental and social well-being and substance use
2022
In the present study, we aimed to explore the relationship between intensity of social media use (SMU), problematic SMU and well-being outcomes. Four categories of SMU were developed taking into account both intensity of use and problematic SMU simultaneously: non-active; active; intense; and problematic use. Using these four categories, we assessed associations between SMU and mental and social well-being, and substance use. Data from 190,089 respondents aged 11, 13, and 15 years from 42 countries involved in the Health Behavior in School-aged Children (HBSC) study were analyzed. With a slight cross-national variance, 78% of adolescents in the sample were classified as active or intense us…
Alteraciones de la Conducta Alimentaria en Pacientes con Trastorno por Abuso de Sustancias
2018
Psychiatric eating disorders (ED) and substance use disorder (SUD) are frequent comorbidities and negatively affect evaluation, treatment, and prognosis of both pathologies. The aim of the present study was to determine the prevalence of eating disorders amongst patients seeking treatment for SUD, mainly alcohol, cocaine, and cannabis, and the modulating role of impulsivity and the presence of the eating restriction disorder. We employed the following evaluation instruments: the Barratt impulsivity scale, the eating disorder inventory (EDI), and the Valencia Addiction to Eating Restriction Questionnaire (CVAR). The results showed that patients with a SUD had higher levels of impulsivity and…
Alterations in eating behavior in patients with substance abuse disorders
2018
RESUMEN La comorbilidad psiquiátrica entre los trastornos de la conducta alimentaria (TCA) y los trastornos por uso de sustancias (TUS) suele darse con frecuencia, complicando el tratamiento y pronóstico de ambos. En el presente trabajo se estudió la prevalencia de los trastornos alimentarios en pacientes que demandan tratamiento por un TUS, principalmente alcohol, cocaína y cannabis, así como el papel modulador de la impulsividad y la adicción a la restricción alimentaria. Los instrumentos utilizados fueron la escala de impulsividad de Barratt, el Inventario de Trastornos Alimenticios (EDI) y el Cuestionario Valencia de Adicción a la Restricción (CVAR). Los resultados muestran que los paci…
Developmental trajectories of emotional disengagement from schoolwork and their longitudinal associations in England
2016
This study identified the varied ways in which emotional disengagement from schoolwork typically developed between 14 and 16 years of age, in the Longitudinal Study of Young People in England. Using growth mixture modelling we found eight main trajectories of (dis)engagement, with four trajectories of either increasing or stable emotional disengagement with schoolwork (41% of the sample). Using propensity score matching to create groups balanced on a wide range of covariates at Wave 1, we compared disengaged students to their engaged counterparts to identify the longitudinal effects of disengagement-trajectory membership on behavioural engagement, psychological wellbeing, substance use, car…
Bupropion induced changes in exploratory and anxiety-like behaviour in NMRI male mice depends on the age
2013
The aim of this study was to assess the effects of the antidepressant bupropion on anxiety and novelty-seeking in adolescent mice of different ages and adults. Behavioural differences between early adolescent, late adolescent and adult NMRI mice were measured both in the elevated plus-maze and the hole-board tasks following acute administration of bupropion (5, 10, 15, 20 mg/kg) or saline. In the plus maze test, early and late adolescent mice treated with bupropion (10, 15 mg/kg, respectively) had lower percentages of entries in the open-arms compared to their vehicle controls. Adult mice treated with bupropion did not differ from their vehicle controls. These results suggest that the effec…
FinnTwin12 Cohort: An Updated Review
2019
AbstractThis review offers an update on research conducted with FinnTwin12 (FT12), the youngest of the three Finnish Twin Cohorts. FT12 was designed as a two-stage study. In the first stage, we conducted multiwave questionnaire research enrolling all eligible twins born in Finland during 1983–1987 along with their biological parents. In stage 2, we intensively studied a subset of these twins with in-school assessments at age 12 and semistructured poly-diagnostic interviews at age 14. At baseline, parents of intensively studied twins were administered the adult version of the interview. Laboratory studies with repeat interviews, neuropsychological tests, and collection of DNA were made of in…
One size doesn’t fit all: a thematic analysis of interviews with people who have stopped participating in Narcotics Anonymous in Norway
2020
Abstract Background For persons with substance use disorders (SUDs), 12-step groups (TSGs) are the most available and used peer-based recovery resource, worldwide. However, disengagement is common, and attrition may partly be due to practices and procedures within these groups that are unacceptable to a portion of the population with SUDs. Our overall aim was to identify problematic issues related to Narcotics Anonymous (NA) participation in Norway, to inform addiction professionals’ strategies when referring persons to addiction-related self-help groups (SHGs). Methods In this qualitative study, we interviewed ten individuals who had previously participated regularly in NA for at least 6 m…
Changing Environmental Influences on Substance Use Across Development
2007
AbstractIn contrast to many phenotypes that have been studied using twin designs, substance use shows considerable evidence of environmental influence. Accordingly, specifying the relevant environments and understanding the nature of their effects is an important research priority. Twin studies also have demonstrated that the importance of genetic and environmental influences varies across development for a variety of behavioral outcomes, including substance use. Here, we report analyses exploring moderating effects associated with parenting and peer characteristics on adolescent smoking and drinking, measured at ages 14 and 17. We find significant evidence of moderating effects associated …