Search results for "Subtype"

showing 10 items of 117 documents

18F-FDG PET-Derived Tumor Blood Flow Changes After 1 Cycle of Neoadjuvant Chemotherapy Predicts Outcome in Triple-Negative Breast Cancer

2016

International audience; Previous studies have suggested that early changes in blood flow (BF) in response to neoadjuvant chemotherapy and evaluated with 150-water are a surrogate biomarker of outcome in women with breast cancer. This study investigates, in the triple-negative breast cancer subtype, the prognostic relevance of tumor BF changes (Delta BF) in response to chemotherapy, assessed using a short dynamic F-18-FDG PET acquisition. Methods: Forty-six consecutive women with triple-negative breast cancer and an indication for neoadjuvant chemotherapy were prospectively included. Women benefited from a baseline F-18-FDG PET examination with a 2-min chest-centered dynamic acquisition, sta…

Oncologymedicine.medical_specialtyPrognostic-FactorsBevacizumabSurvival[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imagingmedicine.medical_treatment[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicineperfusion[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicine030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineBreast cancerbreast cancerInternal medicineMedicineblood flowRadiology Nuclear Medicine and imaging[ SDV.IB ] Life Sciences [q-bio]/BioengineeringTomography[ SDV.IB.IMA ] Life Sciences [q-bio]/Bioengineering/ImagingNeoadjuvant therapyTriple-negative breast cancerSubtypesMarkersChemotherapytriple-negativemedicine.diagnostic_testbusiness.industryTriple Negative Breast Neoplasmsmedicine.disease3. Good healthBevacizumabPETMetabolismPositron emission tomography030220 oncology & carcinogenesisBiomarker (medicine)Pathological Response[SDV.IB]Life Sciences [q-bio]/BioengineeringAngiogenesisTherapybusinessmedicine.drug
researchProduct

Epidemiology of stroke and transient ischemic attacks: Current knowledge and perspectives

2015

International audience; Because of the growing size and aging of the world's population, the global burden of stroke is increasing dramatically. Current epidemiological data indicate that 16.9 million people suffer a stroke each year, which represents a global incidence of 258/100,000 year, with marked differences between high- and low-income countries, and an age-adjusted incidence 1.5 times higher in men than in women. Although primary prevention has contributed to a decrease in stroke incidence in high-income countries, the so-called 'epidemiological transition' has led to an increase in incidence in middle-to-low-income countries as well. In addition, the incidence of ischemic stroke in…

Pediatricsmedicine.medical_specialtyEpidemiologylate 20th-centuryPopulationPsychological intervention030204 cardiovascular system & hematologyGlobal Health03 medical and health sciences0302 clinical medicineetiologic subtypescaribbean population[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyEpidemiologymedicineGlobal healthPrevalenceHumansMortality30-day case-fatalityeducationTransient ischemic attackrisk-factorsStrokeDepression (differential diagnoses)education.field_of_studybusiness.industrycommunity strokeIncidence (epidemiology)Incidencecase-fatality ratesmedicine.disease3. Good healthStrokeEpidemiological transitionNeurologyRisk factorsIschemic Attack Transientquality-of-life1st-ever strokeNeurology (clinical)Francebusiness28-day case-fatality030217 neurology & neurosurgery[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDemography
researchProduct

Cover Feature: Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity (Chem. Eur. J. 47/2020)

2020

Peptide backboneChemistryStereochemistryFeature (computer vision)PeptidomimeticOrganic ChemistryRenin–angiotensin systemClick chemistrySubtype selectivityCover (algebra)General ChemistryCatalysisG protein-coupled receptorChemistry – A European Journal
researchProduct

Normalizing the eating pattern with virtual reality for bulimia nervosa: a case report

2015

AbstractThe aim of the present study was to analyze the effects of a virtual reality (VR) component as a therapeutic tool to normalize eating patterns, as part of the cognitive-behavioral treatment of a bulimia nervosa (BN) patient. Results indicated that the patient made significant progress with her eating habits; binges and vomits were eliminated completely. Moreover, when the VR started the patient avoided food, especially meat (5 over 5), and it was reduction of this avoidance in the lasts sessions (2 and 3 over 5). It was also observed a reduction in the avoidance and the fear of eating (from 10 and 9 to 6 and 5 respectively) and increased the impulse control (from 2 to 7). The patien…

PsychotherapistBulimia nervosaCase studyMotivation to changeVirtual realityTrastornos de la conducta alimentariamedicine.diseaseVirtual realityEstudio de casoRealidad virtualPsychiatry and Mental healthClinical PsychologyGeneral psychopathologySample size determinationEating disordersmedicineDrive for thinnessEating habitsPsychologyBulimia purgative subtypeBulimia nerviosa subtipo purgativoClinical psychologyRevista Mexicana de Trastornos Alimentarios
researchProduct

α1-Adrenoceptors in the rat cerebral cortex: New insights into the characterization of α1L- and α1D-adrenoceptors

2010

36 p., figuras y tablas, bibliografía

Rat cerebral cortexAdrenergic receptorG proteinInositol PhosphatesBiologyAlpha1-adrenoceptor subtypesBinding CompetitiveCytosolReceptors Adrenergic alpha-1medicineAnimalsRNA MessengerRats WistarBinding siteInositol phosphate[3H]prazosin binding studiesCellular localizationCerebral CortexPharmacologychemistry.chemical_classificationReverse Transcriptase Polymerase Chain ReactionCell MembraneRatsCell biologyCytosolmedicine.anatomical_structureGene Expression RegulationBiochemistrychemistryAlpha1L-adrenoceptorsCerebral cortexG-proteinsFemaleGuanosine TriphosphateIntracellularAlpha1D-intracellular localizationEuropean Journal of Pharmacology
researchProduct

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia

2020

Objectives Few studies have analyzed factors associated with delirium subtypes. In this study, we investigate factors associated with subtypes of delirium only in patients with dementia to provide insights on the possible prevention and treatments. Design This is a cross-sectional study nested in the "Delirium Day" study, a nationwide Italian point-prevalence study. Setting and participants Older patients admitted to 205 acute and 92 rehabilitation hospital wards. Measures Delirium was evaluated with the 4-AT and the motor subtypes with the Delirium Motor Subtype Scale. Dementia was defined by the presence of a documented diagnosis in the medical records and/or prescription of acetylcholine…

Rehabilitation hospitalmedicine.medical_specialtyUrinary systemSocio-culturaledementia; elderly; Motor subtypes of delirium; Aged; Cross-Sectional Studies; Humans; Inpatients; Italy; Delirium; Dementiaelderly03 medical and health sciences0302 clinical medicineInternal medicinemental disordersmedicineDementiaMotor subtypes of delirium dementia elderlyHumansdementia elderly Motor subtypes of delirium030212 general & internal medicineLS4_4Medical prescriptionGeneral NursingAgedPsychomotor learningInpatientsbusiness.industryHealth PolicyMedical recordMotor subtypes of deliriumMemantineDeliriumGeneral Medicinemedicine.diseasedementia; elderly; Motor subtypes of deliriumSettore MED/26 - NEUROLOGIACross-Sectional StudiesItalyDeliriumDementiaGeriatrics and Gerontologymedicine.symptombusiness030217 neurology & neurosurgerymedicine.drug
researchProduct

Pathogenic microorganisms carried by migratorybirds passing through the territory of the island ofUstica, Sicily (Italy)

2011

Several studies have shown that migratory birds play an important role in the ecology, circulation and dissemination of pathogenic organisms. In October 2006, a health status evaluation was performed on a large population of migratory birds passing through the territory of Ustica (Italy), an island located on the migration route of many species of birds to Africa, and various laboratory tests were conducted. In total, 218 faecal swabs and the internal organs of 21 subjects found dead in nets were collected for bacteriological and virological examination, including avian influenza and Newcastle disease. In addition, 19 pooled fresh faecal samples were collected for mycological examination. T…

Salmonella bongoriVeterinary medicineCefotaximeNalidixic acidSentinel speciesNewcastle DiseaseDrug ResistanceNewcastle disease virusAnimals WildSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeNewcastle diseaseMicrobiologyBirdsFecesAntibiotic resistanceFood AnimalsYeastsGram-Negative BacteriamedicineDisease Transmission InfectiousAnimalsMigratory birds; Sicily; Viruses; Enterobacteriaceae; Fungi; Antibiotic-resistanceYersinia enterocoliticaSicilyPhylogenyDisease ReservoirsGeneral Immunology and MicrobiologybiologyBird Diseasesavian pathogens migratory birds resistance enterobacteriaceaebiology.organism_classificationInfluenza A virus subtype H5N1Anti-Bacterial AgentsSpecific Pathogen-Free OrganismsInfluenza A virusInfluenza in BirdsAnimal Science and ZoologyAnimal MigrationMitosporic Fungimedicine.drug
researchProduct

Ischemic stroke subtypes and the implications for stroke management

2014

Settore MED/09 - Medicina InternaTOAST subtype Stroke management
researchProduct

18F-FDG PET imaging of breast cancer : evaluation of the metabolic behaviour of the different breast cancer subtypes and prediction of the tumor resp…

2015

Positron Emission Tomography (PET) with 18Fluoro-deoxyglucose (18F-FDG) is the reference imaging examination for in-vivo quantification of the glucidic metabolism of tumour cells. It allows for the monitoring of tumour metabolic changes during chemotherapy. Breast cancer comprises several distinct genomic entities with different biological characteristics and clinical behaviours, leading to different tailored treatments. The aim of this doctoral thesis was to evaluate the relationship between the different biological entities of breast cancer and the tumour metabolic behaviour during neoadjuvant chemotherapy. We have also retrieved, among the various metabolic parameters on PET images, the …

Subtypes[SDV.IB] Life Sciences [q-bio]/BioengineeringFDGPositon EmissionTomographyRéponse tumoraleNeoadjuvant chemotherapyPhénotypesPETBreast cancerTEP[SDV.CAN] Life Sciences [q-bio]/CancerÉvaluationTomographie par Emission de PositonChimiothérapie néoadjucanteTumor responseCancer du sein[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processing
researchProduct

Krūts vēža molekulāro surogātapakštipu klīniski morfoloģiskais raksturojums sievietēm Latvijā un to saistība ar ķirurģiskās ārstēšanas veida izvēli u…

2015

Elektroniskā versija nesatur pielikumus

Surgical treatmentĶirurģiska ārstēšanaBreast cancerKrūts vēzisMedicīna un farmācijaMolekulārie surogātapakštipiVeselības aprūpeSurrogate molecular subtypesMedicīna
researchProduct