Search results for "Successful aging"
showing 4 items of 44 documents
Longitudinal profiles of mental well-being as correlates of successful aging in middle age
2017
This study analyzed the multidimensional (including emotional, psychological, and social well-being) profiles of mental well-being and their links to various indicators of successful aging (SA; including diseases, cognitive and physical function, and engagement with life). The analyses were based on the Finnish Jyväskylä Longitudinal Study of Personality and Social Development, where the age-cohort participants have been followed from age 8 to 50. Data on 335 participants collected in mid-adulthood were analyzed. Applying Latent Profile Analysis and measures of life satisfaction and psychological well-being at ages 36, 42, and 50 and social well-being at ages 42 and 50, four longitudinal w…
Curcumin, inflammation, ageing and age-related diseases
2010
Abstract A Symposium regarding the Pathophysiology of Successful and Unsuccessful Ageing was held in Palermo, Italy between April 7 and 8th 2009. Here the lecture by Sikora with some input from the chairpersons Scapagnini and Barbagallo is summarized. Ageing is manifested by the decreasing health status and increasing probability to acquire age-related disease such as cancer, Alzheimer's disease, atherosclerosis, metabolic disorders and others. They are likely caused by low grade inflammation driven by oxygen stress and manifested by the increased level of pro-inflammatory cytokines such as IL-1, IL-6 and TNF-α, encoded by genes activated by the transcription factor NF-κB. It is believed th…
Conclusions. Slowing aging and fighting age-related diseases, from bench to bedside?
2021
Abstract The multiple wide-ranging and diverse aspects of aging discussed in this volume are overviewed and integrated in order to move toward a better understanding of how to achieve successful aging. To this end, potential strategies capable of slowing aging and preventing age-related diseases are considered and actions proposed.
The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men
2014
The role of nutritional status as determinant of successful aging is very well recognized. There is recent evidence that nutrition may exert its beneficial effects through the modulation of the hormonal anabolic milieu. Under-nutrition and anabolic hormonal deficiency frequently coexist in older individuals determining an increased risk of mobility impairment and adverse outcomes. Mineral dietary assessment has received attention as key component of the nutritional modulation of anabolic status and physical performance. There is evidence that several minerals, including magnesium, exert a positive influence on Insulin-like Growth Factor-1 (IGF-1) secretion in both sexes, and Testosterone (T…