Search results for "SulII"
showing 10 items of 28 documents
Enlarged PLIN5-uncoated lipid droplets in inner regions of skeletal muscle type II fibers associate with type 2 diabetes
2022
Skeletal muscle physiology remains of paramount importance in understanding insulin resistance. Due to its high lipid turnover rates, regulation of intramyocellular lipid droplets (LDs) is a key factor. Perilipin 5 (PLIN5) is one of the most critical agents in such regulation, being often referred as a protector against lipotoxicity and consequent skeletal muscle insulin resistance. We examined area fraction, size, subcellular localization and PLIN5 association of LDs in two fiber types of type 2 diabetic (T2D), obese (OB) and healthy (HC) individuals by means of fluorescence microscopy and image analysis. We found that T2D type II fibers have a significant sub-population of large and inter…
Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?
2022
Objectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors. Design Cross-sectional. Methods A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total f…
Effects of a weight management program delivered by social media on weight and metabolic syndrome risk factors in overweight and obese adults: A rand…
2017
Author(s): Jane, Monica; Hagger, Martin; Foster, Jonathan; Ho, Suleen; Kane, Robert; Pal, Sebely | Abstract: IntroductionThe aim of this project was to evaluate the effectiveness of using social media to augment the delivery of, and provide support for, a weight management program delivered to overweight and obese individuals during a twenty four week intervention.MethodsParticipants randomly divided into either one of two intervention groups or a control group. The two intervention groups were instructed to follow identical weight-management program. One group received the program within a Facebook group, along with a support network with the group, and the other intervention group receive…
Occurrence of Antibiotic Resistance in the Mediterranean Sea
2022
Seawater could be considered a reservoir of antibiotic-resistant bacteria and antibiotic resistance genes. In this communication, we evaluated the presence of bacterial strains in seawater collected from different coasts of Sicily by combining microbiological and molecular methods. Specifically, we isolated viable bacteria that were tested for their antibiotic resistance profile and detected both antibiotic and heavy metal resistance genes. Both antibiotic-resistant Gram-negative bacteria, Vibrio and Aeromonas, and specific antibiotic resistance genes were found in the seawater samples. Alarming levels of resistance were determined towards cefazolin, streptomycin, amoxicillin/clavulanic aci…
Association between cardiorespiratory fitness and metabolic health in overweight and obese adults
2022
BACKGROUND: Cardiorespiratory fitness (CRF) has been inversely associated with insulin resistance and clustering of cardiometabolic risk factors among overweight and obese individuals. However, most previous studies have scaled CRF by body mass (BM) possibly inflating the association between CRF and cardiometabolic health. We investigated the associations of peak oxygen uptake (V̇ O2peak) and peak power output (Wpeak) scaled either by BM-1, fat free mass (FFM-1), or by allometric methods with individual cardiometabolic risk factors and clustering of cardiometabolic risk factors in 55 overweight or obese adults with metabolic syndrome. METHODS: V̇ O2peak and Wpeak were assessed by a maximal …
Effects of a short-term resistance training protocol on risk factors for the metabolic syndrome in the elderly
2016
The metabolic syndrome is strongly associated with negative health outcomes, such as type 2 diabetes, cardiovascular disease and death. The elderly are at particularly high risk of developing the metabolic syndrome, owing to the physiological and behavioural changes associated with aging. The positive influence that resistance training has on the neuromuscular system has long been evident; however, in more recent years, increasing focus has been placed on the role of RT in preventing and treating chronic disease. The majority of studies in the literature suggest that RT has a positive effect on cardiometabolic risk factors. That being said, there remain some inconsistencies. Whether improve…
Liikunnan ja ruokavalion vaikutus hiiren maksa- ja lihaskudoksen hienorakenteeseen : morfometrinen tutkimus
2008
Inter‐individual variation in responses to resistance training in cardiometabolic health indicators
2020
Abstract Resistance training (RT) may improve metabolic health; however, the extent of its effectiveness is constantly evaluated to assess improvements in the group means, thus obscuring the heterogeneous individual effects. This study investigated inter‐individual variation in responses to RT as reflected in metabolic health indicators and how age, sex, nutrition and pre‐training phenotypes are associated with such variabilities. Methods Previously collected data of men and women (39‐73 years, 135 trained, 73 non‐trained controls) were pooled for analysis. Measurements were taken twice before training to estimate individual day‐to‐day variations and measurement errors (n=208). The individu…
Liikunta-aktiivisuuden ja kunnon yhteys insuliiniherkkyyteen 32-37-vuotiailla identtisillä kaksosmiehillä
2014
Mariita Anttila (2014). Liikunta-aktiivisuuden ja kunnon yhteys insuliiniherkkyyteen 32-37-vuotiailla identtisillä kaksosmiehillä. Terveystieteiden laitos, Jyväskylän yliopisto, liikunta-lääketieteen pro gradu-tutkielma, 60 s., 4 liitettä. Liialliset lihaskudoksen ja sisäelinten rasvakertymät, sekä lihasten käyttämättömyyden on todettu heikentävän elimistössä sokerinkulutusta ja insuliinin vaikutusta. Samalla tämä on lisännyt riskiä sairastua aineenvaihduntasairauksiin myös nuoremmilla. Tämän opinnäytetyön tarkoituksena oli tutkia liikunnan, kunnon ja kehonkoostumuksen yhteyttä insuliiniherkkyy-teen 32-37-vuotiailla kaksosmiehillä. Tutkimukseen valikoitui 23 identtistä (MZ) kaksosparia (N=4…
Rikosepäillyn käsittely iltapäivälehdissä Ylöjärven insuliinisurmissa
2011
Tutkin pro gradu -työssäni sitä, miten kuva rikosepäillystä rakentuu iltapäivälehdissä epävi- rallisten lähteiden kautta? Olen kiinnostunut siitä, miten epäiltyyn liittyvät asiat esitetään, mihin ne perustetaan ja otetaanko epäillyn syyllisyyteen kantaa. Tutkittavaksi tapaukseksi olen valinnut kesällä 2007 tapahtuneet Ylöjärven insuliinisurmat ja surmista epäillyn 27- vuotiaan sairaanhoitajan käsittelyn Ilta-Sanomissa ja Iltalehdessä. Olen rajannut aineistoni en- simmäiseen kuukauteen teon julkitulon jälkeen, eli 11.8-11.9. 2007. Tarkasteluni rajoittuu siis rikosepäilyyn, eli aikaan ennen syytteen nostamista tai varsinaista oikeuskäsittelyä. Tutkimuskysymyksellä haluan rajata pois viranomai…