Search results for "Swell"
showing 10 items of 215 documents
Comparison of the efficacy of low doses of methylprednisolone, acetaminophen, and dexketoprofen trometamol on the swelling developed after the remova…
2015
WOS: 000365269900016
Colonic drug delivery: influence of cross-linking agent on pectin beads properties and role of the shell capsule type.
2006
For colonic delivery, pectin beads obtained by ionotropic gelation method have been already reported as an interesting approach. This study investigated the influence of the cross-linking agent (calcium or zinc) and the type of shell capsule used (classical or enteric capsules) on pectin beads properties and on their performance to target the colon (in vitro dissolution studies with subsequent pH change to mimic overall gastro-intestinal tract). Zinc pectinate beads seemed to be relatively similar to calcium's ones in morphological point, except on the surface aspect. When beads were introduced in classical hard capsules, ketoprofen release was not significantly different between CPG and ZP…
Fabric evolution and the related swelling behaviour of a sand/bentonite mixture upon hydro-chemo-mechanical loadings
2015
This experimental study investigates the swelling behaviour of an 80/20 sand/bentonite mixture and the associated fabric evolution under different hydro-chemo-mechanical loadings. Free and confined swelling tests are performed on specimens compacted to different dry densities and wetted with different pore fluids. Controlled suction confined swelling tests are performed to determine the suction–swelling pressure relationship for two different densities. An extensive microstructural characterisation is performed to relate the observed swelling behaviour to the evolution of the different pore networks during wetting. Based on the microstructural analysis, an expression is proposed to determi…
The rheological behaviour of HDPE/LDPE blends. II. Die swell and normal stresses
1984
Die swell data are presented for different high-density/low-density polyethylene blends. The data relating to samples with frozen-in stresses are represented, collected as a function of the usual operational parameters (L/D ratio, flow rate, temperature). Data obtained with annealed samples are used to derive, through a theoretical approach, normal stresses. Die Strahlaufweitung wurde fur verschiedene Mischungen aus Polyethylenen hoher und niedriger Dichte gemessen. Die an Proben mit eingefrorenen Spannungen erhaltenen Werte wurden in Abhangigkeit von technologischen Parametern (Lange/Durchmesser-Verhaltnis, Fliesgeschwindigkeit, Temperatur) dargestellt. An getemperten Proben gemessene Wert…
Highly protective alkalinization by ammonia vapor diffusion in viscosimetric DNA damage assessment.
1988
A method for the measurement of viscosities correlated to DNA alterations in alkaline homogenate suspensions is described. The alkaline pH shift to afford cell lysis, DNA unfolding, and denaturation is attained by gaseous ammonia diffusion, thus avoiding shear stress from mechanical mixing. At the same time a stabilizing density gradient is established. This solution is run through a plastic measuring tube that is wide enough to minimize the influence of uneven swelling of the lysing DNA-containing components. Flow times under a carefully controlled water head are registered, and their ratios to control solutions are evaluated. The relative viscosities show a strong and irreversible depende…
SURFACE AND MECHANISTIC PROPERTIES OF RECYCLED BITUMINOUS MIXTURES
2019
EXECUTIVE SUMMARY Problem Often, when the characteristics of a bituminous mixture are analised, there are major differences between in-lab and in-situ results. This is due to the fact that the procedures and techniques implemented during the design phase (in lab) may be different from those used on site. Then, is very important to be able to predict the main properties of a mixture particularly when innovative materials are used. For example, when crumb rubber is used, phisical and volumetric properties of mixes may change over time, in particular due to the swelling phenomenon that it alters different properties of the mixture (e.g., viscosity). This study aims to investigate the main aspe…
Reversed sexual conflict in a promiscuous antelope.
2007
SummaryA general tenet of sexual conflict theory is that males have higher optimum mating rates than do females and therefore should be more persistent when it comes to mating. However, in promiscuous species, females might benefit from high mating rates as a result of increased conception probability with favored males, whereas favored males benefit from mating selectively because of sperm depletion. When this results in higher optimum mating rates for females than for males, there is potential for reversed sexual conflicts between persistent females and resistant males. Here I report evidence of such a reversed sexual conflict in a promiscuous antelope, the African topi. Rather than matin…
Heterogeneity of osteogenesis imperfecta. Biochemical and morphological findings in a case of type III according to Sillence.
1986
A male infant with pale-blue sclerae, who died at the age of 6 weeks through the aspiration of food, presented multiple fractures and deformation of the long tubular bones. The clinical and radiological findings and the course indicated osteogenesis imperfecta, type III, according to Sillence's classification. The family history was unremarkable. Light and electron microscopic studies of iliac crest bone obtained postmortem, showed an abrupt interruption of endochondral ossification, with an active periosteal ossification. In the region of the fractures, a mixed desmochondral callus was seen. The endoplasmic reticulum of the osteoblasts was markedly dilated, the mitochondria were swollen. T…
Is Dexamethasone superior to Ketorolac in reducing pain, swelling and trismus following mandibular third molar removal? A split mouth triple-blind ra…
2021
Background The preemptive use of anti-inflammatory drugs, such as corticosteroids and NSAIDs, has the potential to reduce pain, swelling and trismus following oral surgery. The aim of this study was to compare the efficacy of dexamethasone and ketorolac tromethamine in reducing pain, swelling and trismus after mandibular third molar removal. Material and Methods The researches implemented a triple-blind, randomized clinical trial. The study was conducted with ASA I individuals aging between 18 and 35 years, which were randomized and submitted to two interventions, one with 8mg dexamethasone and the other with 20mg ketorolac tromethamine given 1h before the procedure. The primary predictor v…
N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: In vivo study with TNBS-induced colitis model in rats
2011
5-Aminosalicylic acid (5-ASA) loaded N-Succinyl-chitosan (SucCH) microparticle and freeze-dried system were prepared as potential delivery systems to the colon. Physicochemical characterization and in vitro release and swelling studies were previously assessed and showed that the two formulations appeared to be good candidates to deliver the drug to the colon. In this work the effectiveness of these two systems in the treatment of inflammatory bowel disease was evaluated. In vitro mucoadhesive studies showed excellent mucoadhesive properties of both the systems to the inflamed colonic mucosa. Experimental colitis was induced by rectal instillation of 2,4,6-trinitrobenzene sulfonic acid (TNB…