Search results for "Synaptic ribbon"

showing 2 items of 22 documents

'TRPing' synaptic ribbon function in the rat pineal gland: neuroendocrine regulation involves the capsaicin receptor TRPV1.

2009

Synaptic ribbons (SRs) are presynaptic structures thought to regulate and facilitate multivesicular release. In the pineal gland, they display a circadian rhythm with higher levels at night paralleling melatonin synthesis. To gain more insight into the processes involved and the possible functions of these structures, a series of experiments were conducted in rodents. We studied the regional distribution of a molecular marker of pineal SRs, the kinesin motor KIF3A in the gland. Respective immunoreactivity was abundant in central regions of the gland where sympathetic fibers were less dense, and vice versa, revealing that intercellular communication between adjacent pinealocytes is enhanced …

endocrine systemmedicine.medical_specialtyEndocrinology Diabetes and MetabolismTRPV1KinesinsTRPV Cation ChannelsBiologyBradykininPineal GlandCalcium in biologyPinealocyteMembrane PotentialsMelatoninRats Sprague-DawleyCellular and Molecular Neurosciencechemistry.chemical_compoundPineal glandNorepinephrineEndocrinologyInternal medicinemedicineAnimalsMelatoninSynaptic ribbonEndocrine and Autonomic SystemsRatsEndocrinologymedicine.anatomical_structurenervous systemchemistrySynapseslipids (amino acids peptides and proteins)CalciumCapsaicinCapsazepineEndocrine glandmedicine.drugNeuroendocrinology
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Development of day-night rhythmicity in "synaptic" ribbon numbers in the pinealocytes of posthatch chicks kept under either natural photoperiodic con…

1991

: Pineal synaptic ribbons (SR) undergo characteristic changes over a period of 24 hr under natural photoperiodic conditions in various vertebrates, being low in number during daytime and elevated at night. During posthatch development of chicks, the rhythmicity of SR numbers is reported to appear at the age of about 2 weeks. Because the influence of external light during the growth phase of chicks on the development of day-night rhythmicity in SR numbers is unknown, we studied day-night differences in SR numbers in the pinealocytes of chicks at the posthatch ages of 15, 17, and 19 days; chicks had previously been kept under natural photoperiodic conditions or continuous illumination. Under …

endocrine systemmedicine.medical_specialtyanimal structuresOntogenyPeriod (gene)Cell CountBiologyNocturnalPineal GlandPinealocyteMelatoninEndocrinologyInternal medicinemedicineAnimalsCircadian rhythmLightingphotoperiodismSynaptic ribbonCircadian RhythmEndocrinologyembryonic structuresSynaptic VesiclesChickensPhotic Stimulationmedicine.drugJournal of Pineal Research
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