Search results for "Systematic"

Heterologe Transplantation des Ehrlich-Aszites-Karzinoms von der unbehandelten Maus auf die unbehandelte oder r�ntgenganzbestrahlte Ratte

1956

Bestimmung von Sorbit-Dehydrogenase und Creatin-Phosphokinase im Serum von lathyritischen und mit Prednison behandelten lathyritischen Ratten

1965

Ca++-, Hypothermie- und pH-Effekte auf den mechanischen Systolenbeginn des isolierten Herzens

1966

Erratum: Pérez-Belmonte, S., et al. Subtypes of Depression: Latent Class Analysis in Spanish Old People with Depressive Symptoms. Life 2020, 10, 70

2020

The authors wish to make the following erratum to this paper [...]

Scratching beneath 'The Scratching Case': systematic reviews and meta-analyses, the back door for evidence-based medicine

2014

Endometrial scratching or injury was first suggested a decade ago as a simple intervention to improve endometrial receptivity in patients undergoing ART. More than a decade later, based on weak evidence some doctors have adopted this strategy, although there is not yet agreement about its real benefit. In this opinion paper, we analyze the methodological and plausibility problem beneath 'the Scratching Case'. This is also applicable to several other examples of spurious associations reported in the literature. In particular, we emphasize what should be done so as not to dilute evidence-based medicine by a vicious circle created by the over-exploitation of inadequate or insufficient data to …

Connectedness and connectivity of the Natura 2000 network of protected areas across country borders in the European Union

2012

Abstract We studied the spatial connectedness of Natura 2000 site boundaries and the functional connectivity of the Natura 2000 network across the 34 terrestrial borders of the European Union. Connectivity was measured by the dispersal success of 192 reptile, amphibian, invertebrate and plant species from Annex II of the European Union Habitats Directive, based on the presence of same species on both sides of the borders. Connectedness and connectivity varied greatly between state borders, with good and bad examples found in all parts of the European Union. Connectedness and connectivity were positively correlated. However, a few outlying examples showed that good connectedness is not neces…

Intellectual capital and business model: a systematic literature review to explore their linkages

2020

PurposeIn the last decades, business and management scholars have given great attention to intellectual capital (IC), which could seem a mature topic, having arrived at its third wave of studies. However, its intersections with the business model (BM) remain an under-investigated topic, and the authors wanted to investigate two research questions (RQs): how the literature addressing IC and BM has evolved so far in the business and management domains? What are possible future research trends of business and management studies regarding IC and BM?Design/methodology/approachThis study answers these questions through a systematic literature review (SLR) of 74 peer-reviewed articles in the area …

Titanium plate removal in orthognathic surgery: prevalence, causes and risk factors. A systematic literature review and meta-analysis

2020

The purpose of this review was to analyse the prevalence of titanium plate removal in orthognathic surgery, as well as the causes of plate removal, and to determine the associated risk factors. A thorough search of the PubMed, Scopus, Embase, and Web of Science databases was conducted. The inclusion criteria were studies of adult patients who underwent orthognathic surgery in which monocortical titanium plates and screws were placed. Of the 325 references identified, 19 were included in the qualitative synthesis and meta-analysis. Overall, 13.4% (95% confidence interval (CI) 9.6-18.3%) of the patients required the removal of at least one titanium plate; 9.7% (95% CI 6.3-14.6%) of the plates…

Spinal Cord Stimulation to Treat Unresponsive Cancer Pain: A Possible Solution in Palliative Oncological Therapy

2022

(1) Background: Treatment of cancer-related pain is still challenging, and it can be managed by both medical and interventional therapies. Spinal Cord Stimulation (SCS) is a minimally invasive technique, and its use is rapidly increasing in the treatment of chronic pain. (2) Materials and Methods: Our study aims to perform a review of the pertinent literature about current evidences in cancer pain treatment by Spinal Cord Stimulation. Moreover, we created a database based on case reports or case series (18 studies) in the literature. We analyzed a clinical group of oncological patients affected by intractable pain undergoing SCS implantation, focusing on outcome. (3) Results: The analysis o…

STEM CELLS FOR TREATMENT OF CARDIOVASCULAR DISEASES: AN UMBRELLA REVIEW OF RANDOMIZED CONTROLLED TRIALS

2021

AIMS:\ud \ud Stem cells are a promising therapy for various medical conditions. The literature regarding their adoption for the clinical care of cardiovascular diseases (CVD) is still conflicting. Therefore, our aim is to assess the strength and credibility of the evidence on clinical outcomes and application of stem cells derived from systematic reviews and meta-analyses of intervention studies in CVD.\ud \ud METHODS and RESULTS:\ud \ud Umbrella review of systematic reviews with meta-analyses of randomized controlled trials (RCTs) using placebo/no intervention as control group. For meta-analyses of RCTs, outcomes with a random-effect p-value< 0.05, the GRADE (Grading of Recommendations Ass…