Search results for "Systems"

showing 10 items of 11952 documents

Femtosecond laser versus mechanical microkeratome laser in situ keratomileusis for myopia: Metaanalysis of randomized controlled trials.

2011

Purpose To examine differences in efficacy, accuracy, safety, and changes in aberrations between femtosecond and mechanical microkeratome laser in situ keratomileusis (LASIK) for myopia. Setting Department of Ophthalmology, Shanghai First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China. Design Evidence-based manuscript. Methods Data sources, including PubMed, Medline, EMBASE, and Cochrane Controlled Trials Register, were searched to identify potentially relevant prospective randomized controlled trials. Primary outcome measures were efficacy (uncorrected distance visual acuity ≥20/20), accuracy (±0.50 diopter mean spherical equivalent), and safety (loss of ≥2 l…

Adultmedicine.medical_specialtyCorneal Wavefront Aberrationgenetic structuresDatabases Factualmedicine.medical_treatmentCorneal StromaKeratomileusis Laser In SituVisual AcuityKeratomileusisRefraction OcularSensitivity and Specificitylaw.inventionYoung AdultPostoperative ComplicationsRandomized controlled triallawMicrokeratomemedicineMyopiaHumansRegistriesDioptreRandomized Controlled Trials as TopicEquipment Safetybusiness.industryLASIKReproducibility of ResultsOdds ratioMiddle Agedeye diseasesSensory SystemsConfidence intervalSurgeryOphthalmologyTreatment OutcomeMeta-analysisSurgeryLasers ExcimerbusinessJournal of cataract and refractive surgery
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Cost analysis of target-controlled infusion-based anesthesia compared with standard anesthesia regimens.

2000

UNLABELLED With the development of new computer-assisted target-controlled infusion (TCI) systems and the availability of short-acting anesthetics, total IV anesthesia (TIVA) has become increasingly popular. The aim of this study was to compare costs of TCI-based anesthesia with two standard anesthesia regimens. Sixty patients undergoing elective laparoscopic cholecystectomy were randomly divided into three groups. Group 1 (TIVA/TCI) received TIVA using a propofol-based TCI system and continuous administration of remifentanil; Group 2 (isoflurane) underwent inhaled anesthesia with isoflurane, fentanyl, and N2O; Group 3 (standard propofol) received fentanyl and N2O and a continuous infusion …

Adultmedicine.medical_specialtyCost-Benefit AnalysisRemifentanilAnesthesia GeneralFentanylPacuRemifentanilDrug Delivery SystemsPiperidinesMedicineHumansInfusions IntravenousPropofolInfusion PumpsAgedbiologyIsofluranebusiness.industryMiddle Agedbiology.organism_classificationSurgeryFentanylRegimenAnesthesiology and Pain MedicineIsofluraneAnesthesiaAnestheticAnesthetics Inhalationmedicine.symptombusinessPropofolPostoperative nausea and vomitingAnesthetics Intravenousmedicine.drugAnesthesia and analgesia
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Collagen copolymer posterior chamber phakic intraocular lens for hyperopia correction: three-year follow-up.

2013

Purpose To assess the efficacy, predictability, safety, and stability of the Visian V3 Implantable Collamer Lens posterior chamber phakic intraocular lens (PC pIOL) for moderate to high hyperopia. Setting Private clinic, Oviedo, Spain. Design Prospective nonrandomized clinical study. Methods The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, manifest refraction, endothelial cell density, intraocular pressure (IOP), central vault, and adverse events were evaluated for 3 years postoperatively. Results The study comprised 73 eyes of 44 patients. The mean spherical equivalent decreased from +4.84 diopters (D) ± 1.6 (SD) (range +1.00 to +7.75 D) preoperatively to −0.13 ± 0.39 …

Adultmedicine.medical_specialtyIntraocular pressurePhakic Intraocular Lensesgenetic structuresVisual AcuitySpherical equivalentBiocompatible MaterialsCell CountRefraction OcularSafety indexCorneaYoung AdultLens Implantation IntraocularOphthalmologymedicineHumansProspective StudiesDioptreImplantable collamer lensEfficacy indexbusiness.industryEndothelium CornealMiddle Agedeye diseasesSensory SystemsPosterior chamber phakic intraocular lensEndothelial cell densityOphthalmologyHyperopiaTreatment OutcomeSurgerysense organsCollagenbusinessFollow-Up StudiesJournal of cataract and refractive surgery
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Vascular modifications within a choroidal osteoma

1993

We report a case of choroidal osteoma followed-up for 7 years. During this lapse of time the choroidal osteoma showed slight enlargement, development of subretinal hemorrhage and modifications of intratumoral vascularization. Some large intratumoral vessels visible at first examination disappeared at follow-up, while other vessels not observed before developed. The changes in the vascularization of the choroidal osteoma denote profound dynamics in the processes of osseous rearrangement of the tumor.

Adultmedicine.medical_specialtyPathologyChoristomaBone and BonesPhysiology (medical)Subretinal hemorrhagemedicineHumansOsteomaNeovascularization Pathologicmedicine.diagnostic_testChoroidbusiness.industryOsteomaRetinal HemorrhageChoroid DiseasesChoroidal osteomaFluorescein angiographymedicine.diseaseeye diseasesSensory Systemsbody regionsOphthalmologymedicine.anatomical_structureAngiographyFemalesense organsChoroidRadiologyUltrasonographybusinessFollow-Up StudiesDocumenta Ophthalmologica
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Whole-body vibration and disorders of the spine

1987

This cross-sectional study is based on interviews and medical examinations of 352 operators of earth-moving machines who had been exposed to whole-body vibrations for at least three years. In addition, available X-rays showing different parts of the spines of 251 machine operators who had been exposed to vibration for at least ten years were used for evaluation. One hundred and forty-nine of the operators were asked about discomfort occurring immediately after an eight-hour work shift. The group of exposed persons was compared with a control group of 215 non-exposed persons. The percentage of subjects reporting spinal discomfort was much higher for the exposed group than for the non-exposed…

Adultmedicine.medical_specialtyRehabilitationCross-sectional studybusiness.industrymedicine.medical_treatmentPublic Health Environmental and Occupational HealthOccupational diseaseMiddle Agedmedicine.diseaseVibrationOccupational DiseasesRadiographyCross-Sectional StudiesLumbarEpidemiologymedicinePhysical therapyEtiologyHumansWhole body vibrationSpinal DiseasesbusinessMan-Machine SystemsRachisInternational Archives of Occupational and Environmental Health
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Liposomal-encapsulated doxorubicin plus cyclophosphamide as first-line therapy in metastatic breast cancer: a phase II multicentric study

2007

Abstract Background The objective of this study is to evaluate the efficacy and toxicity of the liposome-encapsulated doxorubicin (TLC D-99) plus cyclophosphamide (CTX) as first-line treatment of metastatic breast cancer in light of the potential cardioprotective effect of TLC D-99 as compared with conventional doxorubicin. Materials and methods Sixty-seven patients as defined according Simon's two-stage phase II design were enrolled. They received TLC D-99 at the dosage of 60 mg/m2 plus CTX 600 mg/m2, with cycles repeated every 3 weeks. Cardiac function was assessed by ultrasonography at baseline and every two cycles. Results The principal characteristics of the 67 enrolled patients were a…

Adultmedicine.medical_specialtySkin NeoplasmsCyclophosphamideSettore MED/06 - Oncologia MedicaPhases of clinical researchBreast NeoplasmsSoft Tissue NeoplasmsAsymptomaticGastroenterologyDrug Delivery SystemsBreast cancerInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineMucositisHumansAntineoplastic Agents AlkylatingCyclophosphamideAgedAntibiotics AntineoplasticPerformance statusbusiness.industryHematologyMiddle Agedmedicine.diseasedoxorubicin cyclophosphamide breast cancerMetastatic breast cancerSurgeryOncologyDoxorubicinLiposomesToxicityCarcinoma Squamous CellFemalemedicine.symptombusinessmedicine.drug
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Mismatch negativity during objective and subjective sleepiness.

1997

The mismatch negativity (MMN) and P3 of auditory event-related potentials were studied during subjectively and objectively (physiologically) defined sleepiness under optimal stimulus conditions for MMN elicitation. The MMN and P3 were elicited by either small or large unattended auditory deviants presented to the left ear. The participant's task was to detect either rare auditory targets presented to the right ear or rare changes in the light flashes. Eleven young adults served as participants in a nighttime experiment. The MMN declined especially at Fz and Cz but not so markedly at the right mastoid as either subjective or objective alertness decreased. The amplitude of P3 also decreased d…

Adultmedicine.medical_specialtySleep stateCognitive Neurosciencemedia_common.quotation_subjectMismatch negativityExperimental and Cognitive PsychologyStimulus (physiology)Audiologybehavioral disciplines and activitiesDevelopmental psychologyDevelopmental NeuroscienceEvent-related potentialmedicineReaction TimeHumansAttentionBiological Psychiatrymedia_commonEndocrine and Autonomic SystemsElectromyographyGeneral NeuroscienceElectroencephalographyElectrophysiologyAlertnessElectrooculographyNeuropsychology and Physiological PsychologyNeurologyAcoustic StimulationEvoked Potentials Auditorymedicine.symptomPsychologySleeppsychological phenomena and processesSomnolenceVigilance (psychology)Psychophysiology
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Sympathetic activity at rest and motor brain areas: FDG-PET study.

2008

Although recent studies identified brain areas which are involved in short term activation of the sympathetic nervous system, little is known about brain mechanisms which generate the individual variability of basal autonomic activity. In this fluorodeoxyglucose positron emission tomography study (FDG-PET), we aimed to identify brain regions, which covary with function parameters of the autonomic nervous system at rest. Therefore, FDG-PET (Siemens, Germany) was performed twice in 14 healthy resting subjects (7 m, 7 f; mean age 29.5 years) while different parameters of autonomic function were assessed simultaneously: Blood pressure, heart rate, power spectra of heart rate variability (HF/LF …

Adultmedicine.medical_specialtySympathetic nervous systemSympathetic Nervous SystemRestBlood PressureCellular and Molecular NeuroscienceMuscle toneNorepinephrineFluorodeoxyglucose F18Heart RateInternal medicineHeart ratemedicineHeart rate variabilityHumansAttentionChromatography High Pressure LiquidEndocrine and Autonomic SystemsBrainAutonomic nervous systemmedicine.anatomical_structureEndocrinologyBlood pressureGlucosePositron-Emission TomographyNeurology (clinical)Primary motor cortexRadiopharmaceuticalsPsychologyMotor cortexAutonomic neuroscience : basicclinical
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Assessment of the implantation of day-2 human embryos by morphometric nonsubjective parameters

2014

Objective: To demonstrate the usefulness of image analysis in designing objective embryonic morphometric variables. Design: Retrospective study of 214 top-quality day-2 embryo photographs from 50 double-embryo transfers resulting in no pregnancy (group 0) and 57 resulting in twin pregnancy (group 1). Setting: Human reproduction unit. Patient(s): Study of 107 in vitro fertilization intracytoplasmic sperm injection (IVF ICSI) cycles in women age<36 years with doubleembryo transfer of top-quality embryos. Only the first cycle of IVF ICSI was included. Intervention(s): Standard IVF ICSI protocols. Main Outcome Measure(s): The embryo photographs were analyzed using the ImageJ program. The effect…

Adultmedicine.medical_specialtyTime Factorsanimal structuresESTADISTICA E INVESTIGACION OPERATIVAFertilization in VitroBiologyPRODUCCION ANIMALEmbryo grading systemsPredictive Value of TestsPregnancymedicineOdds RatioHumansSperm Injections Intracytoplasmicreproductive and urinary physiologyRetrospective StudiesGynecologyEmbryo scoreurogenital systemMorphological and morphometric embryo variablesAge FactorsObstetrics and GynecologyEmbryoAnatomyEmbryo TransferEmbryo MammalianLogistic ModelsReproductive Medicineembryonic structuresEmbryo implantationPregnancy TwinFemaleEmbryo selectionImages analysis
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Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)

2011

The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has been assumed in the control of clitoral vascular smooth muscle. As only a few investigations on the physiology of the vascular and non-vascular clitoral tissue have been carried out, knowledge on the mechanisms controlling this particular female genital organ is still vague. It has been suggested that human clitoral corpus cavernosum smooth muscle is regulated by nitric oxide (NO)/cyclic GMP and related key enzymes, such as NO synthases (NOSs) and the phosphodiesterase type 5 (PDE5). The present study evaluated in the human clitoris, by means of immunohistochemistr…

Adultmedicine.medical_specialtyVascular smooth muscleStromal cellAdolescentNitric Oxide Synthase Type IIIUrologyClitorisBiologyEndothelial NOSSecond Messenger SystemsClitorisNitric oxideYoung Adultchemistry.chemical_compoundInternal medicineCyclic GMP-Dependent Protein KinasesmedicineHumansVimentinProtein kinase ACyclic GMPCyclic guanosine monophosphateCyclic Nucleotide Phosphodiesterases Type 5Cyclic Nucleotide Phosphodiesterases Type 2Immunohistochemistrymedicine.anatomical_structureEndocrinologychemistrycGMP-specific phosphodiesterase type 5FemaleInternational Journal of Impotence Research
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