Search results for "TAILS"

Application and development of ion-source technology for radiation-effects testing of electronics

2017

Abstract Studies of heavy-ion induced single event effect (SEE) on space electronics are necessary to verify the operation of the components in the harsh radiation environment. These studies are conducted by using high-energy heavy-ion beams to simulate the radiation effects in space. The ion beams are accelerated as so-called ion cocktails, containing several ion beam species with similar mass-to-charge ratio, covering a wide range of linear energy transfer (LET) values also present in space. The use of cocktails enables fast switching between beam species during testing. Production of these high-energy ion cocktails poses challenging requirements to the ion sources because in most laborat…

Impact of burn-out syndrome in oncology personnel and its improvement through specific interventions

2019

Abstract Background Burn-Out Syndrome (BOS) in oncology nurses, has few experiences reported about its incidence and impact in its three different areas: emotional and physical exhaustion, cynism and despersonalization and no personal nor profesional fulfillment. There is a lack of resources for its diagnosis and management, although it impacts negatively in the patient attention/ care quality and the quality of institutional processes, added the personal impact in personal workers lives. Our objective was to determine the incidence of the BOS in our workers, analyze its causes and reduce in 20% the percentage of workers suffering or at risk of suffering BOS. Methods 23 nurses / nurse assis…

High-overtone bulk acoustic resonator as passive ground penetrating RADAR cooperative targets

2013

International audience; RAdio-frequency Detection And Ranging instruments—RADARs—are widely used for applications aimed at measuring passive target velocity or ranging for various metrology applications such as ground position and localization. Within the context of using piezoelectric acoustic passive sensors as cooperative targets to RADARs probed through a radiofrequency link, this paper reports on investigating the compatibility of narrowband resonator architectures with the classical operation mode of wideband RADAR instruments. Since single mode resonators are hardly compatible due to the limited bandwidth of their spectrum, the investigation has been extended to High-overtone Bulk Ac…

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10

2012

The in vivo roles of meprin metalloproteases in pathophysiological conditions remain elusive. Substrates define protease roles. Therefore, to identify natural substrates for human meprin α and β we employed TAILS (terminal amine isotopic labeling of substrates), a proteomics approach that enriches for N-terminal peptides of proteins and cleavage fragments. Of the 151 new extracellular substrates we identified, it was notable that ADAM10 (a disintegrin and metalloprotease domain-containing protein 10)—the constitutive α-secretase—is activated by meprin β through cleavage of the propeptide. To validate this cleavage event, we expressed recombinant proADAM10 and after preincubation with meprin…

Sequentially Forecasting Economic Indices Using Mixture Linear Combinations of EP Distributions

2021

This article displays an application of the statistical method moti- vated by Bruno de Finetti's operational subjective theory of probability. We use exchangeable forecasting distributions based on mixtures of linear com- binations of exponential power (EP) distributions to forecast the sequence of daily rates of return from the Dow-Jones index of stock prices over a 20 year period. The operational subjective statistical method for comparing distributions is quite different from that commonly used in data analysis, because it rejects the basic tenets underlying the practice of hypothesis test- ing. In its place, proper scoring rules for forecast distributions are used to assess the values o…

Evaluation of Daylight Availability for Energy Savings.

2015

Dynamic daylight simulations are very useful instruments in daylighting design process. They allow an in depth analysis of indoor daylight availability levels and define if they are adequate to perform a particular visual task. Their results can be used to design shading devices or lighting control systems and compare different technical solutions. The use of these simulations is likely to spread in the common design practice since some regulations and green building rating systems suggest their use. This paper presents dynamic daylight simulation results related to an open-plan office, performed with Autodesk 3ds Max Design ® , which is a calculation software validated by recent researches…

Fractional calculus approach to the statistical characterization of random variables and vectors

2009

Fractional moments have been investigated by many authors to represent the density of univariate and bivariate random variables in different contexts. Fractional moments are indeed important when the density of the random variable has inverse power-law tails and, consequently, it lacks integer order moments. In this paper, starting from the Mellin transform of the characteristic function and by fractional calculus method we present a new perspective on the statistics of random variables. Introducing the class of complex moments, that include both integer and fractional moments, we show that every random variable can be represented within this approach, even if its integer moments diverge. A…

Senti chi parla. Su un aspetto dell’attività di parola a partire da Lacan.

2017

Continuous Discharge Monitoring Using Non-contact Methods for Velocity Measurements: Uncertainty Analysis

2014

At gauged site, water stage and discharge hydrographs can be related also during unsteady flow conditions, using the one-dimensional diffusive hydraulic model, DORA, and exploiting sporadic surface velocity measurements carried out with a radar sensor, during the rising limb of the flood. Indeed, starting from the measured surface velocity, the application of a simplified entropic velocity distribution model allows obtaining the benchmark discharge for the Manning’s roughness calibration. The aim of this work is twofold. First, to address the uncertainty of the approach. Second, to detect the minimum water level along the rising limb in which the occasional surface velocity measurement shou…

Show me your tail, if you have one! Is inbreeding depression occurring in wildcats (Felis silvestris silvestris) from Italy?

2022

Knowledge of genetic diversity is important to wildlife conservation because genetically depleted populations experience an increased risk of extinction. Mammalian carnivores are characterized by small and fragmented populations and low dispersal, so that genetic erosion can lead to the fixation of deleterious genes relatively quickly, leading to morphological abnormalities. Kinked tails and cowlicks are indicative of inbreeding depression and have been described in two wild cat species so far, the puma (Puma concolor) and the cheetah (Acinonyx jubatus). Here we report the first records of morphological abnormalities in five populations of the European wildcat (Felis silvestris silvestris) …