Search results for "TAM"

Evaluation of biodegradability of novel polymeric nanoparticles based on amphiphilic polylactide-polyaspartamide derivatives.

2015

Desymmetrization of Prochiral Cyclobutanones via Nitrogen Insertion: A Concise Route to Chiral γ‐Lactams

2021

Abstract Asymmetric access to γ‐lactams is achieved via a cyclobutanone ring expansion using widely available (1S,2R)‐1‐amino‐2‐indanol for chiral induction. Mechanistic analysis of the key N,O‐ketal rearrangement reveals a Curtin–Hammett scenario, which enables a downstream stereoinduction (up to 88:12 dr) and is corroborated by spectroscopic, crystallographic, and computational studies. In combination with an easy deprotection protocol, this operationally simple sequence allows the synthesis of a range of optically pure γ‐lactams, including those bearing all‐carbon quaternary stereocenters. In addition, the formal synthesis of drug molecules baclofen, brivaracetam, and pregabalin further …

Tracce di ‘improbus intestabilisque’ nella Parafrasi di Teofilo e nei Basilici

2017

The research is a part of a wider study on the improbitas and the so called intestabilitas in the Roman sources and focuses on analysis of a passage of the Theophilus’Paraphrase (2.10.6) and some σχόλια added to the Basilica [especially, Sch. 1 ad Bas. 39.1(Pb).6 e Sch. 3 ad Bas. 21.1(Pa).14] – texts that have not been taken into account (except for PT. 2.10.6 only) by the scholars who studied the implications associated with the improbus intestabilisque esse. The Author aims to verify the presence of traces of that institute in the aforementioned Byzantine sources, which may be useful for a more complete reconstruction of the historical evolution of the Roman formulaic improbus intestabili…

Žako van Dormela filmu “Mr Nobody” un “Le tout nouveau testament” simboli cilvēku uztverē

2018

Bakalaura darba tēma ir “Žako van Dormela filmu “Mr Nobody” un “Le tout nouveau testament” simboli cilvēku uztverē”. Par bakalaura darba pētījuma problēmu tiek uzskatīta simbolu uztveres daudzveidība. Par bakalaura darba problēmjautājumu tika izvirzīts jautājums, kā režisora Žako van Dormela abu filmu skatītāji uztver simbolus un zīmes, kas ir pamanāmas filmās. Bakalaura darba mērķi ir noskaidrot, kādi simboli ir pamanāmi filmās, un kā tie izpaužas, kādus simbolus pamana abu filmu skatītāji, un kāda ir simbolu nozīme filmās.Darbā teorētisko bāzi veidos sekojošas teorijas – kino teorija, vizuālā komunikācija, filmu mērķauditorija, simbolu komunikācija, semiotika un semiotika kino. Darba meto…