Search results for "TAVI"
showing 10 items of 342 documents
Intracellular delivery of baculovirus and streptavidin-based vectors in vitro : towards novel therapeutic applications
2008
Geeniterapia on kokeellinen lääketieteellinen hoitomuoto, jonka pyrkimyksenä on korvata solujen perintöaineksen puuttuva tai vaurioitunut geeni ja sen tuote. Toistaiseksi geeniterapian kliiniset kokeet ovat kohdistuneet pääasiassa syövän, sydän- ja verisuonisairauksien ja yksittäisten geenivirheiden aiheuttamien sairauksien hoitoon.Geenien kuljettamiseen soluihin, kudoksiin tai elimiin käytetään joko synteettisiä tai virusperäisiä kuljettimia. Kuljettimien kehittämisessä kuhunkin tautimalliin sopivaksi on kuitenkin vielä monia haasteita, kuten syntyvät immuniteettireaktiot sekä hoitogeenin ilmentymisen riittävä tehokkuus kohdekudoksessa. Johanna Laakkonen seurasi väitöstutkimuksessaan lupaa…
Uuden bakteeriperäisen avidiinin sukulaisproteiinin tuottaminen, puhdistus sekä sen ominaisuuksien määrittäminen
2007
Internalization of novel non-viral vector TAT-streptavidin into human cells
2007
Background. The cell-penetrating peptide derived from the Human immunodeficiency virus-1 transactivator protein Tat possesses the capacity to promote the effective uptake of various cargo molecules across the plasma membrane in vitro and in vivo. The objective of this study was to characterize the uptake and delivery mechanisms of a novel streptavidin fusion construct, TAT47–57-streptavidin (TAT-SA, 60 kD). SA represents a potentially useful TAT-fusion partner due to its ability to perform as a versatile intracellular delivery vector for a wide array of biotinylated molecules or cargoes. Results. By confocal and immunoelectron microscopy the majority of internalized TAT-SA was shown to accu…
Koeteltavien markkinoiden teoria ja tietokonevarausjärjestelmät : miksi teorian oletukset eivät toteudu Yhdysvaltain sisäisessä reittilentoliikentees…
1997
Söderskogin verollepanokartan suunnitelma
1699
saatu Timo Meriluodolta
Gender and development - no-man's land revisited : learning from men's inclusion discourse and practice in Uganda
2006
«Antaviana»: del text narratiu al text dramàtic
2015
The author studies the changes taken place in the stories which have given rise to the theatrical play in its passage from the genres of narrative to drama, from narrated history to performed history.
The Predictors of Literacy Skills among Monolingual and Bilingual Finnish–Swedish Children During First Grade
2021
The aim of the study was to examine which predictor variables are related to literacy skills among monolingual Swedish (n = 269) and bilingual Finnish–Swedish (n = 229) children at the first grade in the Swedish-speaking schools in Finland. The participants were assessed in phonological awareness, letter knowledge, rapid automatized naming (RAN), word recognition, reading fluency, and spelling. The results showed that RAN was the most significant predictor of reading and spelling skills in both language groups, and monolingual children performed significantly better in RAN. Moreover, letter knowledge predicted reading and spelling skills in both groups. However, no significant differences b…
Er sluttbrukere forberedt på elektronisk kurve? : Sluttbrukeres erfaring med opplæring i elektronisk kurve og medikasjon
2019
Masteroppgave helse- og sosialinformatikk HSI500 - Universitetet i Agder 2019 BackgroundAs part of the digitalisation of health Norway, a newdigital system is introduced for the documentation of clinical protocolsand medication throughout the Helse Sør-ØstRHF. The system MetaVision replaces today's paper solutions and a few cases of other electronic systems on all health establishments. In that context, there are thousands of employees who needs to be trained. While large sums of money are being used on clinical-ICT in health care, there is little evidence of what works and what doesn't work when it comes to training. The purpose of the project is to look at this. The following issue is the…