Search results for "TB"

"Table 25" of "Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in $pp$ collisions at $\sqrt{s} =13$ TeV w…

2020

Expected upper limits on cross-section times branching fraction of Kaluza-Klein gluon decaying into top-quark pair as a function of the width of Kaluza-Klein gluon for masses of 5 TeV.

"Table 22" of "Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in $pp$ collisions at $\sqrt{s} =13$ TeV w…

2020

Expected and observed upper limits on cross-section times branching fraction of Kaluza-Klein gluon decaying into top-quark pair as a function of the width of Kaluza-Klein gluon for masses of 1 TeV.

"Table 23" of "Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in $pp$ collisions at $\sqrt{s} =13$ TeV w…

2020

Expected and observed upper limits on cross-section times branching fraction of Kaluza-Klein gluon decaying into top-quark pair as a function of the width of Kaluza-Klein gluon for masses of 1.5 TeV.

"Table 24" of "Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in $pp$ collisions at $\sqrt{s} =13$ TeV w…

2020

Expected upper limits on cross-section times branching fraction of Kaluza-Klein gluon decaying into top-quark pair as a function of the width of Kaluza-Klein gluon for masses of 2 TeV.

"Table 21" of "Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in $pp$ collisions at $\sqrt{s} =13$ TeV w…

2020

Expected and observed upper limits on cross-section times branching fraction of Kaluza-Klein gluon decaying into top-quark pair as a function of the width of Kaluza-Klein gluon for masses of 0.5 TeV.

Novel Group a Rotavirus G8 P[1] as Primary Cause of an Ovine Diarrhoeic Syndrome Outbreak in Weaned Lambs

2010

Molecular epidemiology and forensic genetics: application to a hepatitis C virus transmission event at a hemodialysis unit.

2002

Molecular phylogenetic analyses are frequently used in epidemiologic testing, although only occasionally in forensics. Their acceptability is hampered by a lack of statistical confidence in the conclusions. However, maximum likelihood testing provides a sound statistical framework for the testing of phylogenetic hypotheses relevant for forensic analysis. We present the results of applying this method to a small hepatitis C outbreak produced in a hospital hemodialysis unit that involved 6 patients. Polymerase chain reaction products from a 472-nt fragment of the E1-E2 region, including the hypervariable region, HVR-1, of the hepatitis C virus genome were cloned, and an average of 10 clones/p…

The effects of inbreeding on mortality during a morbillivirus outbreak in the Mediterranean striped dolphin (Stenella coeruleoalba)

2004

Between 1990 and 1992, Mediterranean striped dolphins ( Stenella coeruleoalba ) suffered high mortality due to a morbillivirus epidemic. Ten highly variable microsatellite markers were used to assess the population structure of a sample of these stranded animals and to assess the genetic consequences of the epizootic on present stocks. We found little evidence of population structure within the Mediterranean, but distinct separation between this and the North Sea (Atlantic) population, the latter also showing greater genetic diversity. Using a genetic measure of inbreeding, we found that dolphins dying early in the outbreak were significantly more inbred than those dying later. Within 10 ye…

Macro- and microgeographic genetic structure in an ant species with alternative reproductive tactics in sexuals

2011

The genetic structure of social insect populations is influenced by their social organization and dispersal modes. The ant Hypoponera opacior shows diverse reproductive behaviours with regular cycles of outbreeding via winged sexuals and inbreeding via within-nest mating wingless sexuals that reproduce by budding. This unusual life cycle should be reflected in the genetic population structure, and we studied this on different scales using microsatellites. On a macrogeographic scale, populations were considerably structured and migration rates within the Chiricahuas were higher than those in between mountain ranges. On a local scale, our analyses revealed population viscosity through depende…

Putative Breast Cancer Driver Mutations in TBX3 Cause Impaired Transcriptional Repression

2015

The closely related T-box transcription factors TBX2 and TBX3 are frequently overexpressed in melanoma and various types of human cancers, in particular, breast cancer. The overexpression of TBX2 and TBX3 can have several cellular effects, among them suppression of senescence, promotion of epithelial–mesenchymal transition, and invasive cell motility. In contrast, loss of function of TBX3 and most other human T-box genes causes developmental haploinsufficiency syndromes. Stephens and colleagues (1), by exome sequencing of breast tumor samples, identified five different mutations in TBX3, all affecting the DNA-binding T-domain. One in-frame deletion of a single amino acid, p.N212delN, was ob…