Search results for "TDC"

Transcranial Electrical and Magnetic Stimulation (tES and TMS) for Addiction Medicine: A Consensus Paper on the Present State of the Science and the …

2019

International audience; There is growing interest in non-invasive brain stimulation (NIBS) as a novel treatment option for substance-use disorders (SUDs). Recent momentum stems from a foundation of preclinical neuroscience demonstrating links between neural circuits and drug consuming behavior, as well as recent FDA-approval of NIBS treatments for mental health disorders that share overlapping pathology with SUDs. As with any emerging field, enthusiasm must be tempered by reason; lessons learned from the past should be prudently applied to future therapies. Here, an international ensemble of experts provides an overview of the state of transcranial-electrical (tES) and transcranial-magnetic…

STIMA DEL POTENZIALE ELETTRICO IN tDCS CON APPROCCIO MESHLESS INNOVATIVO

2015

Transcranial DC stimulation (transcranial Direct Current Stimulation, tDCS) is a non-invasive technique aimed at modifying neuronal activity for the purpose therapeutic and / or for the improvement of mental performance. A continuous current of entity modest (below the threshold of perception) is injected into the brain via electrodes placed on the scalp surface to produce changes in long-term cortical activity. Despite the increasing use of this and other similar techniques, and the relevant ones applications - for example in the field of neuropsychological rehabilitation - their impact on neuronal activity is not yet fully known, mainly due to the difficulty of predict the spatial distrib…

MEMORIA MOTORIA Protocollo di riabilitazione cognitiva dei disturbi del movimento, il ruolo della corteccia motoria primaria. Utilizzo di metodiche d…

l'obiettivo della presenti tesi è stato quello di verificare il ruolo della corteccia motoria primaria in un test cognitivo di memorizzazione e riconoscimento di immagini di movimento suddivisi in sequenza. Sono stati utilizzati strumenti di modulazione dell'attività cerebrale quali la TMS ( stimolazione magnetica transcranica) e per la registrazione dei MEP (potenziali evocati motori) e la tDCS (stimolazione cerebrale a corrente diretta) e per la modulazione dell'attività cerebrale durante lo svolgimento del compito cognitivo. Questi studi sono stati condotti grazie alla partecipazione di soggetti sani e soggetti con lesione cerebrale dell'emisfero desrtro. I risultati ottenuti sembrano di…

Transcranial direct current stimulation (TDCS) can modulate esophageal motility in gatroesophageal reflux disease (GERD)patients.

2012

TRANSCRANIAL DIRECT STIMULATION (TDCS) CAN MODULATE ESOPHAGEAL MOTILITY IN GASTROESOPHAGEAL REFLUX DISEASE (GERD) PATIENTS

2012

TRANSCRANIAL DIRECT STIMULATION (tcds) CAN MODULATE ESOPHAGEAL MOTILITY IN GASTRO-ESOPHAGEAL REFLUX DISEASE (GERD) PATIENTS

2012

Clinical effects of different montages of Transcranial Direct Current Stimulation (tDCS) in patients with Parkinson’s Disease

2016

Background: Parkinson’s disease (PD) is characterized by motor deficits which may not completely respond to the dopaminergic therapy, thus posing a therapeutic challenge. Non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have shown promising results as possible alternative of treatment in different neurological disorders including PD. The therapeutic effect of tDCS, which may increase (anodal currents) or decrease (cathodal currents) the cortical excitability level, likely relies on modulation of cortico-subcortical interactions and abnormal patterns of cortical activation. Objective: To investigate safety and therapeutic potential of different…

Functional connectivity modulation induced by transcranial direct current stimulation of the motor network: a Resting-State fMRI study

2016

Resting-state functional connectivity represents a novel fMRI approach that allows detection of temporal correlations in spontaneous BOLD signal oscillations while subjects rest quietly in the scanner. Functional connectivity (FC) can be defined as the synchrony of neural activity among spatially distant regions. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions. This study is aimed at measuring the variation of functional connectivity between cortical brain regions after tDCS along time. The temporal concatenation group ICA showed that immediately after anodal stimulation the a…

SHORT-TERM SYNAPTIC PLASTICITY IN MIGRAINE MOTOR CORTEX: EVIDENCE BY PRECONDITIONING OF HIGH-FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (…

2011

Background: Brief 5Hz repetitive transcranial magnetic stimulation (rTMS) trains at 120% of the resting- motorthreshold (RMT) intensity determine in healthy subjects a potentiation of motor evoked potentials (MEPs), likely due to short-term presynaptic plasticity facilitation. We recently showed paradoxical intensity-dependent MEP changes to 5Hz rTMS in migraine with MEP facilitation at 110% and inhibition at 130% RMT. This provides evidence of both hyper-responsivity and self-limiting hyperexcitability capacity in migraine, likely due to earlier activation of inhibitory homeostatic plasticity mechanisms. To explore this, we applied in migraineurs cathodal transcranial Direct Current Stimul…

A Hooke's law-based approach to protein folding rate

2014

Kinetics is a key aspect of the renowned protein folding problem. Here, we propose a comprehensive approach to folding kinetics where a polypeptide chain is assumed to behave as an elastic material described by the Hooke[U+05F3]s law. A novel parameter called elastic-folding constant results from our model and is suggested to distinguish between protein with two-state and multi-state folding pathways. A contact-free descriptor, named folding degree, is introduced as a suitable structural feature to study protein-folding kinetics. This approach generalizes the observed correlations between varieties of structural descriptors with the folding rate constant. Additionally several comparisons am…