Search results for "TECNOLOGICO"
showing 10 items of 440 documents
ATRP AS AN EFFICIENT METHOD TO PRODUCE BRUSH COPOLYMERS OF HYALURONIC ACID
2012
Casein-loaded proteoliposomes: novel delivery strategy to inhibit Aβ1-40 fibrillogenesis in Alzheimer disease
2018
Background: Alzheimer's disease (AD) is a chronic and progressive syndrome, which represents the most common cause of dementia worldwide. A pathological and characteristic AD hallmark is the deposition of amyloid plaques, composed by well-ordered amyloid β-peptide (Aβ) fibers, in brain tissue. The Aβ aggregation process follows typical nucleation-polymerization kinetics, characterized by structural intermediates with specific dimensions, morphologies and cytotoxic activity. Some evidences shifted researchers’ attention to smaller soluble Aβ prefibrillar oligomers as they result the most toxic species. Therefore, novel therapeutic strategies target oligomers or prefibrillar aggregates rather…
GALACTOSE-DECORATED POLYMERIC CARRIERS FOR HEPATOCYTE-SELECTIVE DRUG TARGETING
2015
In this paper, the current available strategies to realize galactose-decorated nanostructured polymeric systems are summarized. These carriers are designed in order to obtain targeted drug delivery to hepatocytes via galactose (GAL) moieties, i.e., for the treatment of viral hepatitis or liver cancer that are the greater causes of global disability and mortality. Usually, the main followed strategy to obtain galactosylated polymeric carriers is to use galactosylated copolymers. The chemical modifications of preformed polymers with sugar-containing reagents is followed for obtaining lactosaminated human albumin, galactosylated phospholipid-polyaminoacid and polylactide (PLA)- polyaminoacid c…
ATTIVITÀ ANTIBATTERICA DI UNA SOLUZIONE OLEOSA: possibili applicazioni nell’industria alimentare per la prevenzione della formazione di biofilm
2014
Le malattie che derivano dal consumo di alimenti hanno sempre minacciato la salute umana. Oggi il loro aumento è diventato un problema per salute pubblica, emergente in tutto il mondo. Molte di queste malattie sono state associate alla presenza di biofilm batterici, comunità microbiche complesse, nell’industria alimentare. Il biofilm è diventato un grosso problema per l’industria della lavorazione del pesce, del latte e derivati, del pollame, della carne e dei cibi “pronti da mangiare”, perché, in seguito alla sua formazione, i batteri a esso associati sono particolarmente resistenti agli agenti antimicrobici e alle operazioni di pulizia. Anche se fino ad oggi sono ancora utilizzate, e sono…
Oregano essential oils activity against Listeria monocitogenes biofilms
2015
Ocular Drug Delivery Systems per la veicolazione di molecole bioattive al segmento posteriore dell'occhio
Buccal delivery in treatment of Alzheimer disease: enhancement of galantamine absorption
2009
CURCUMIN-LOADED LIPID NANOSTRUCTURES AS DRUG DELIVERY SYSTEMS.
2009
Characterization Of Casein-Loaded Proteoliposomes, Potential Inhibitors In Amyloid Fibrillogenesis
Casein-loaded proteoliposomes: Drug Delivery Systems and Potential Inhibitors in Aβ1-40 Fibrillogenesis
2018
Alzheimer's disease (AD) represents the most common cause of dementia worldwide. The early symptom is usually a short-term memory loss, followed by symptoms including problems with language, disorientation, mood swings, loss of motivation, not managing self-care, and behavioral issues, until loss of body functions and, ultimately, death. The cause of AD is poorly understood and the diagnosis is complex. One of the main AD hallmarks is the extracellular deposition in brain tissue of proteinaceous amyloid plaques, composed by well-ordered fibrillary aggregates of the amyloid β-peptide (Aβ). The Aβ aggregation process follows typical nucleation-polymerization kinetics, characterized by structu…