Search results for "TEP"
showing 10 items of 712 documents
Pharmacological and chemical features ofNepetaL. genus: Its importance as a therapeutic agent
2017
Medicinal plants have always had great value for the human population due to their valuable constituents and potential bioactivities. The objective of this review is to present an updated overview of an important medicinal plant genus Nepeta L., from the family Lamiaceae, revealing its traditional utilization, biological activity, phytoconstituents, and mechanisms of action. For this purpose, a literature survey was carried out by using SciFinder, ScienceDirect, Scopus, PubMed, and Web of Science followed by a revision of the bibliographies of the related articles. We have described and analyzed the role of plants in drug discovery and the importance of Nepeta species. Information on the ut…
PI-Extension of porphyrins via intramolecular aromatic oxidative C-N coupling
2019
Π-extension of porphyrins has been performed via intramolecular oxidative C-N coupling of peripheral pyridinyl fragment(s) with the porphyrin core. These fusion reactions lead to the formation of C-N bond(s) between the substituent(s) and the porphyrin. The precursors were functionnalized with 2-mercaptopyridine, 8-hydoxyquinoline and 2-picoline at their meso or β-pyrrolic positions via aromatic nucleophlic substitution, cross-coupling reaction or reaction of the macrocycle with organolithium reagents. Voltametric analyses revealed some marked differences on the reactivity of the porphyrins depending on their substitution pattern and metalation (nickel(II) or zinc(II)). Chemical and electro…
Synthèse de nouveaux agents bimodaux hydrosolubles pour l'IRM, l'imagerie nucléaire, l'imagerie biphotonique et la génération de second harmonique
2015
The goal of my PhD studies was to synthesize new compounds for possible medical imaging applications. The first part of my thesis focused on the synthesis of heteroleptic ligands to achieve the chelation of two different metals aimed at addressing two types of medical imaging. We first synthesized porphyrins, which are well-known for the chelation of numerous transition metals. We focused on copper, whose copper-64 isotope is a β+ emitter usable in Positron Emission Tomography (PET). These porphyrins have been coupled with a DOTA derivative. This molecule, metallated with gadolinium, is well-known in Magnetic Resonance Imaging (MRI). Our compounds display encouraging relaxivities for MRI ap…
Productidinid brachiopods (Strophomenata, Productida), including Martinezchaconia luisae, new genus and new species of Linoproductidae, from the Carb…
2018
We describe three brachiopod species of the Suborder Productidina from the Ixtaltepec Formation, Carboniferous of the north of Oaxaca State, southern Mexico, found in peri-reef deposits. Stegacanthia bowsheri and Undaria sp. are members of the families Sentosiidae and Monticuliferidae respectively and were found in strata of the Visean (Middle Mississippian). Martinezchaconia luisae, new genus and species of the Family Linoproductidae, was recollected in Bashkirian-Moscovian (Lower-Middle Pennsylvanian) strata. The respective ages are inferred from the index species of brachiopods associated with the productidines herein described.
Quantification of electrochromic kinetics by analysis of RGB digital video images
2018
A new, rapid, and practical procedure to obtain quantitative kinetic information of electrochromic materials is proposed. When the transition between two colors on a colored electrode surface is monitorized by digital video, the analysis of pixel color intensity (I) in sequential RGB digital images allows us to precise the half-life time (t1/2) of the color change since a maximum value of the standard deviation of the pixel intensity (σ(I)) is reached. We simulated and analyzed the evolution of standard deviation during an electrochromic transition in different circumstances (kinetic and diffusion control). As an example of application, electrochromic transitions of a thin film model, the P…
Work-home interaction from a work psychological perspective: Development and validation of a new questionnaire, the SWING
2005
Contains fulltext : 54536.pdf (Publisher’s version ) (Closed access) This paper reports on the stepwise development of a new questionnaire for measuring work-home interaction, i.e. the Survey Work-home Interaction—NijmeGen, the SWING). Inspired by insights from work psychology, more specifically from Effort-Recovery Theory (Meijman & Mulder, 1998), we defined work-home interaction by differentiating between the direction and quality of influence. Four types of work-home interaction were distinguished and measured by using 22 (including 13 self-developed) items. By using data from five independent samples (total N=2472), validity evidence was provided based on the internal structure of the q…
Endring i psykisk velvære etter gjennomført 12-trinnsbasert rusbehandling : en sammenligning av dag- og døgnbehandling
2014
Masteroppgave i psykisk helsearbeid ME504 Universitetet i Agder 2014 Background There has been an increasing focus on intensive outpatient treatment in drug rehabilitation. Through Government papers, the Norwegian authorities emphasize holistic and integrated services at the lowest effective level of care. And that the treatment of those with co-occurring substance abuse and mental disorders, which is defined out of dual diagnosis, must be strengthened. 12-step treatment is an internationally recognized therapy form treating alcoholism and substance abuse, but it is less focused on whether the treatment form contributes to improved mental health. Aims The study is based on 136 patients admi…
Physical inactivity in patients with COPD, a controlled multi-center pilot-study
2010
Physical activity (PA) has been reported to be reduced in severe chronic obstructive pulmonary disease (COPD). Studies in moderate COPD are currently scarce. The aim of the present study was to investigate physical activity in daily life in patients with COPD (n=70) and controls (n=30).A multi-center controlled study was conducted. PA was assessed using a multisensor armband device (SenseWear, BodyMedia, Pittsburgh, PA) and is reported as the average number of steps per day, and the time spent in mild and moderate physical activity.Patients suffered from mild (n=9), moderate (n=28), severe (n=23) and very severe (n=10) COPD. The time spent in activities with mild (80 + or - 69 min vs 160 + …
Improved identification of thrombolysis candidates amongst intermediate-risk pulmonary embolism patients: implications for future trials.
2017
Defining a “higher-risk” population among intermediate-risk patients with pulmonary embolism included in PEITHO http://ow.ly/JM7u30hcSgN
Molecular barcoding for central-eastern European Crioceris leaf-beetles (Coleoptera: Chrysomelidae)
2011
Abstract Among Crioceris leaf-beetles, the two most widespread species (Crioceris asparagi and C. duodecimpunctata) are serious invasive plant pests, while another two (C. quatuordecimpunctata and C. quinquepunctata) are rare species restricted to steppe-like habitats in Eurasia. The aim of the research was to check the genetic distinctiveness of these four species and develop barcodes for their molecular identification using the mitochondrial Cytochrome Oxidase I (COI) gene and two nuclear markers: Elongation Factor 1-α (EF1-α) and Internal Transcribed Spacer 1 (ITS1). The identification of each species was possible and reliable with the use of COI and ITS1 markers. EF1-α was omitted in an…