Search results for "TEP"

Refractometric sensor based on whispering-gallery modes of thin capillarie.

2009

Whispering-gallery modes resonances of submicron wall thickness capillaries exhibit very large wavelength shifts as a function of the refractive index of the medium that fills the inside. The sensitivity to refractive index changes is larger than in other optical microcavities as microspheres, microdisks and microrings. The outer surface where total internal reflection takes place remains always in air, enabling the measure of refractive index values higher than the refractive index of the capillary material. The fabrication of capillaries with submicron wall thickness has required the development of a specific technique. A refractometer with a response higher than 390 nm per refractive ind…

Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation

2022

Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing factors to cardiac fibrosis and heart failure. We hypothesized that this conversion could be also mediated by response of these cells to mechanical cues through activation of the Hippo transcriptional pathway. The objective of the present study was to assess the role of cellular/nuclear straining forces acting in myofibroblast differentiation of cardiac stromal cells under the control of YAP (yes-associated protein) transcription factor and to validate this finding using a pharmacological agent that interf…

Air Traffic, Boarding and Scaling Exponents

2014

The air traffic is a very important part of the global transportation network. In distinction from vehicular traffic, the boarding of an airplane is a significant part of the whole transportation process. Here we study an airplane boarding model, introduced in 2012 by Frette and Hemmer, with the aim to determine precisely the asymptotic power–law scaling behavior of the mean boarding time 〈t b 〉 and other related quantities for large number of passengers N. Our analysis is based on an exact enumeration for small system sizes N ≤ 14 and Monte Carlo simulation data for very large system sizes up to \(N = 2^{16} = 65,536\). It shows that the asymptotic power–law scaling 〈t b 〉 ∝ N α holds with…

Photosynthesis in Lichen: Light Reactions and Protective Mechanisms

2012

Lichens are symbiotic associations (holobionts) established between fungi (mycobionts) and certain groups of cyanobacteria or unicellular green algae (photobionts). This symbiotic association has been essential in establishing the colonization of terrestrial and consequently dry habitats. About 44 genera of algae and cyanobacteria have been reported as lichen photobionts. Due to the uncertain taxonomy of many of these photobionts, these numbers were considered as approximations only. Ahmadjian (1993) estimates that only 25 genera were typical lichen photobionts. The most common cyanobionts are Nostoc, Scytonema, Stigonema, Gloeocapsa, and Calothrix, in order of frequency (Budel, 1992). Gree…

A facile chemoenzymatic approach: one-step syntheses of monoterpenoid indole alkaloids.

2010

Facile chemoenzymatic syntheses of cytotoxic monoterpenoid indole alkaloids with novel skeletons and multiple chiral centers are described. Synthesis of these alkaloids was achieved by a simple one-step reaction using strictosidine and 12-aza-strictosidine as the key intermediates. Strictosidines were prepared by coupling of secologanin with tryptamine and 7-aza-tryptamine, respectively, using the immobilized recombinant Rauvolfia strictosidine synthase. A detailed stereochemical analysis is presented herein. The results provide an opportunity for a chemoenzymatic approach that leads to an increased diversification of complex alkaloids with improved structures and activities.

18F-FDG PET for breast cancer : combined analysis of tumour perfusion and metabolism for tumour characterisation and neoadjuvant chemotherapy respons…

2020

Neoadjuvant chemotherapy (NAC) is a common treatment in patients with locally advanced or large breast cancer at diagnosis. A pathological complete response (pCR) at the end of NAC is recognized as a good surrogate marker of relapse-free survival. An early identification of the pathological response has then become a key parameter to monitor new therapeutic strategies. Studies, focusing on predictive biomarkers identification, have shown that early changes in tumour metabolism, assessed by Positron Emission Tomography (PET) using 2-desoxy-2-18F-fluoro-D-glucose (18F-FDG), allow the early assessment of the pathological response at the end of treatment. However, given the diversity of breast …

Predictive Study of Heat Transfer to an Incompressible Fluid Past a Downstream-Facing Step in Turbulent Flow

1988

Magmatism Along Lateral Slab Edges: Insights From the Diamante-Enotrio-Ovidio Volcanic-Intrusive Complex (Southern Tyrrhenian Sea)

2019

Volcanic‐intrusive complexes often formed along lateral slab edges as a consequence of subduction‐induced mantle flow. We investigate this process in the southern Tyrrhenian Sea by integrating multibeam bathymetry, seismic‐reflection data, regional magnetic anomalies data, and seismological data. The interpretation of the data highlights the presence of magmatic intrusions that locally reach the seafloor forming volcanic edifices. Chimneys, lava flows, and laccoliths are observed beneath and surrounding the volcanoes. The emplacement and cooling of the magma occurred during the Brunhes Chron. The volcanoes are not active even if the hydrothermal activity occurs. The volcanic‐intrusive compl…

Like barn leker mest, men er det best? : Integrering av enslige mindreårige gjennom fritidsaktiviteter

2016

Master thesis development management - University of Agder 2016

Shear bond strength of one-step self-etch adhesives to dentin: Evaluation of NaOCl pretreatment

2018

Background The aim of this study was to evaluate the influence of dentin pretreatment with NaOCl on shear bond strength of four one-step self-etch adhesives with different pH values. Material and methods Bovine permanent incisors were used. Four one-step self-etch adhesives were tested: Adper™ Easy Bond, Futurabond NR, G-aenial Bond, Clearfil S3 Bond. One two-step self-etch adhesive (Clearfil SE Bond) was used as control. Group 1- no pretreatment; group 2- pretratment with 5,25 % NaOCl; group 3- pretreatment with 37 % H3PO4 etching and 5,25 % NaOCl. A hybrid composite resin was inserted into the dentin surface. The specimens were tested in a universal testing machine. The examiners evaluate…