Search results for "TERMINATION"
showing 10 items of 780 documents
Dendritic localization of mammalian neuralized mRNA encoding a protein with transcription repression activities.
2002
Drosophila neurogenic gene neuralized (neu) is required for the maintenance of neuroblast cell fate and differentiation. In the present study we have characterized a mouse and a rat homologue of Drosophila neu. Mammalian neu1 encodes several C-terminal RING zinc finger proteins with one or two neuralized homology repeat (NHR) domains. Mammalian neu1 mRNAs are predominantly expressed in the nervous system and in the skeletal muscle with the highest levels in the adult. In the nervous system neu1 mRNAs are expressed in neurons and dendritically localized in several brain regions, suggesting a role of neu1 in the regulation of synaptic function. Mammalian neu1 isoforms exhibit transcription re…
Bioplastics: A new analytical challenge
2022
Even though petroleum-based plastics are advantageous in complying with the performance requirements in many applications, these are related, throughout their life cycle, to several environmental problems, including greenhouse gas emissions and persistence in marine and terrestrial environments. Therefore, the preservation of natural resources and climate change is considered worldwide, the main reason for which is necessary to reduce consumption and dependence on fossil-based materials. Biopolymers (PLA, PHAs, etc.) are examples of plastics whose use is grown exponentially over the years because of the improvements of their physical and mechanical properties using additives of various natu…
Good-genes effects in sexual selection
1999
The magnitude of the effect of good genes as a viability benefit accruing to choosy females remains a controversial theoretical and empirical issue. We collected all available data from the literature to estimate the magnitude of good-genes viability effects, while adjusting for sample size. The average correlation coefficient between male traits and offspring survival in 22 studies was 0.122, which differed highly significantly from zero. This implies that male characters chosen by females reveal on average 1.5% of the variance in viability. The studies demonstrated considerable heterogeneity in effect size; some of this heterogeneity could be accounted for by differences among taxa (birds…
Isolation, characterization and sequence determination of Noda virus from sea bass (Dicentrarchus labraxL.) reared in freshwater and marine facilitie…
2017
Σκοπός της παρούσας μeλέτης ήταν η απομόνωση του ίου Noda από ιχθυeς γλυκού νeρού και eιδικά από το eίδος Dicentrarchus labrax L. (λαβράκι) και ο μοριακός χαρακτηρισμός του. Σe προηγούμeνeς μeλέτeς έχeι αναφeρθeί η ανίχνeυση του ίου Noda μe τη μέθοδο της Αλυσιδωτής Αντίδρασης της Πολυμeράσης (ΑΑΠ) σe λαβράκια (Dicentrarchus labrax) που eμφάνιζαν κλινικά συμπτώματα και eκτρέφονταν υπό eντατικές συνθήκeς σe γλυκό νeρό. Δeν eίχe, όμως, eπιτeυχθeί η απομόνωση του σe κυτταροκαλλιέργeια. Η παρούσα μeλέτη πeριγράφeι την απομόνωση του ίου Noda από eλληνικές eκτροφές λαβρακιου που eμφάνιζαν κλινικά συμπτώματα και που eκτρέφονταν τόσο σe θαλάσσιο όσο και σe γλυκό νeρό. Ο ιός απομονώθηκe στην e…
RAD SNP markers as a tool for conservation of dolphinfish Coryphaena hippurus in the Mediterranean Sea: Identification of subtle genetic structure an…
2016
Dolphinfish is an important fish species for both commercial and sport fishing, but so far limited information is available on genetic variability and pattern of differentiation of dolphinfish populations in the Mediterranean basin. Recently developed techniques allow genome-wide identification of genetic markers for better understanding of population structure in species with limited genome information. Using restriction-site associated DNA analysis we successfully genotyped 140 individuals of dolphinfish from eight locations in the Mediterranean Sea at 3324 SNP loci. We identified 311 sex-related loci that were used to assess sex-ratio in dolphinfish populations. In addition, we identifie…
A comparison of two indirect methods for estimating average levels of gene flow using microsatellite data.
1999
We compare the performance of Nm estimates based on FST and RST obtained from microsatellite data using simulations of the stepwise mutation model with range constraints in allele size classes. The results of the simulations suggest that the use of microsatellite loci can lead to serious overestimations of Nm, particularly when population sizes are large (N5000) and range constraints are high (K20). The simulations also indicate that, when population sizes are small (N/= 500) and migration rates are moderate (Nm approximately 2), violations to the assumption used to derive the Nm estimators lead to biased results. Under ideal conditions, i.e. large sample sizes (ns/= 50) and many loci (nl/=…
Sampling and repeatability in the evaluation of hepatitis C virus genetic variability.
2003
Among the experimental techniques available to study the genetic variability of RNA virus populations, the most informative involve reverse transcription (RT), amplification, cloning and sequencing. The effects of several aspects of these techniques on the estimation of genetic variability in a virus population were analysed. Hepatitis C virus populations from four patients were examined. For each patient, ten series of data derived from independent PCR amplifications of a single RT reaction were obtained. The sample size of each data set was 10 sequences (in nine series) and 100 sequences (in one series). An additional data set derived from an independent RT reaction (about 10 sequences) p…
CARDIOVASCULAR DISEASE RISKS AND FACTORS INFLUENCING THEM AMONG MEDICAL COLLEGE STUDENTS
2016
The aim of the study is to identify the CVD risks among medical college students associating them to their lifestyle. It should be noted that cardiovascular diseases also affect young people, which students are also. Information obtained during research is necessary for prospective medical staff to acknowledge their cardiovascular health and its influencing factors, as well as for college lecturers to make changes in study programs. The theoretical part of the research discusses various CVD risk determination methods, as well as lifestyle`s impact on cardiovascular health. The empirical part of the research contains information about ten years CVD risk among students, using two Framingham m…
Physical Activity Interventions and Their Effects on Cognitive Function in People with Dementia: A Systematic Review and Meta-Analysis.
2021
Background: Physical activity (PA) has emerged as an alternative nonpharmacological approach to effectively address the effects of dementia. The primary aim was to identify and summarize PA interventions and their effects on cognitive function among persons with dementia (PwD). Methods: A systematic review was conducted with a meta-analysis using different electronic databases, such as PubMed, Embase, APA PsycNET, and the Web of Science. The identified and selected studies were randomized controlled trials (RCTs) that were written in English, published between 2000 and 2020, and implemented among PwD who received a PA intervention and whose cognitive function was measured at baseline and du…
2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents.
2016
Increasing prevalence of hypertension (HTN) in children and adolescents has become a significant public health issue driving a considerable amount of research. Aspects discussed in this document include advances in the definition of HTN in 16 year or older, clinical significance of isolated systolic HTN in youth, the importance of out of office and central blood pressure measurement, new risk factors for HTN, methods to assess vascular phenotypes, clustering of cardiovascular risk factors and treatment strategies among others. The recommendations of the present document synthesize a considerable amount of scientific data and clinical experience and represent the best clinical wisdom upon wh…