Search results for "TFs"
showing 6 items of 6 documents
Thioredoxin (Trxo1) interacts with proliferating cell nuclear antigen (PCNA) and its overexpression affects the growth of tobacco cell culture.
2017
Thioredoxins (Trxs), key components of cellular redox regulation, act by controlling the redox status of many target proteins, and have been shown to play an essential role in cell survival and growth. The presence of a Trx system in the nucleus has received little attention in plants, and the nuclear targets of plant Trxs have not been conclusively identified. Thus, very little is known about the function of Trxs in this cellular compartment. Previously, we studied the intracellular localization of PsTrxo1 and confirmed its presence in mitochondria and, interestingly, in the nucleus under standard growth conditions. In investigating the nuclear function of PsTrxo1 we identified proliferati…
Mājas tīkla un servera izveide ar Windows Server 2016
2017
Kvalifikācijas darbā apskatītas mājsaimniecības privātā tīkla funkcionalitātes nepilnības un to risinājumu iespējas izmantojot izvēlēto sistēmu – Windows Server 2016. Darba mērķis ir uzlabot esošo LAN tīklu drošības un funkcionalitātes aspektā. Darba kontekstā risinātās problēmas ir aktuāls jautājums mūsdienu mājsaimniecībās, kur privāto tīklu veido vairāk kā 2-3 darbstacijas, mobilās iekārtas, tiek izmantota bezvadu piekļuve internetam un lietotāju starpā ir bērni. Darba teorētiskajā daļā veikta esošā mājas tīkla iekārtu un sistēmu izpēte, lai nodrošinātu piemērotākā risinājuma ieviešanu. Kā arī definēti darba gaitā izpildāmie uzdevumi, vadoties pēc lietotāju stāstiem. Darba praktiskajā da…
Liver injury, SARS‐COV‐2 infection and COVID‐19: What physicians should really know?
2021
Abstract Background & Aims Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is responsible for coronavirus disease 2019 (COVID‐19), which in males, especially in advanced age, can sometimes evolve into acute respiratory distress syndrome. In addition, mild to moderate alterations in liver function tests (LFTs) have been reported in the worst affected patients. Our review aims to analyse data on the incidence and prognostic value of LFT alterations, the underlying mechanisms and the management of pre‐existing liver disease in COVID‐19 affected patients. Methods We searched available literature through online PubMed database using terms as “SARS‐CoV‐2,” “Liver damage,” “Liver Func…
Conductive films of ordered nanowire arrays
2004
peer-reviewed High-density, ordered arrays of germanium nanowires have been synthesised within the pores of mesoporous thin films (MTFs) and anodized aluminium oxide (AAO) matrices using a supercritical fluid solution-phase inclusion technique. Conductive atomic force microscopy (C-AFM) was utilised to study the electrical properties of the nanowires within these arrays. Nearly all of the semiconductor nanowires contained within the AAO substrates were found to be conducting. Additionally, each individual nanowire within the substrate possessed similar electrical properties demonstrating that the nanowires are continuous and reproducible within each pore. C-AFM was also able to probe the co…
Humectabilidad In-Vivo E In-Vitro En Diferentes Materiales De Lentes De Contacto Y Calidad De La Película Lagrimal
2023
Las lentes de contacto han aumentado en popularidad en las últimas cinco décadas como una opción para la corrección de los errores refractivos del ojo, con un estimado de 140 millones de usuarios en todo el mundo. A pesar de la introducción de nuevas tecnologías y materiales de las lentes de contacto, la interrupción y/o “deserción” en el porte continúa causando problemas a la industria de la contactología. La sequedad y el malestar relacionados con las lentes de contacto continúan siendo reportados por aproximadamente el 30% y 50% de los portadores de lentes, principalmente las molestias al final del día. Una encuesta reciente indico que el 25% de los encuestados habían descontinuado el po…
Initiator-Directed Transcription: Fission Yeast Nmtl Initiator Directs Preinitiation Complex Formation and Transcriptional Initiation
2022
The initiator element is a core promoter element encompassing the transcription start site, which is found in yeast, Drosophila, and human promoters. This element is observed in TATA-less promoters. Several studies have defined transcription factor requirements and additional cofactors that are needed for transcription initiation of initiator-containing promoters. However, those studies have been performed with additional core promoters in addition to the initiator. In this work, we have defined the pathway of preinitiation complex formation on the fission yeast nmt1 gene promoter, which contains a functional initiator with striking similarity to the initiator of the human dihydrofolate red…